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The Telomere Effect: A Revolutionary Approach to Living Younger, Healthier, Longer
by Dr Elissa Epel Dr Elizabeth BlackburnA groundbreaking book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life.Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free).THE TELOMERE EFFECT reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. THE TELOMERE EFFECT will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.
The Telomere Miracle: Scientific Secrets To Fight Disease, Feel Great, And Turn Back The Clock On Aging
by Ed ParkWhat if everything you think you know about getting older and staying healthy is wrong? Ed Park, M.D., offers the revolutionary idea that disease and aging in humans all arises from a single source: genetic errors caused by shortening of telomeres, or the sequences of DNA at the ends of our chromosomes. Telomeres naturally wear down over time, and thus when cells replicate (as they do all the time in our bodies), they’re creating progressively poorer-quality duplicates of themselves, like making a Xerox of a Xerox of a Xerox. Ultimately, the body deteriorates, resulting in a range of ailments, many of which we associate with aging—from diabetes to hypertension to macular degeneration to cancer. Happily, Ed tells us, it’s possible to slow or even reverse this process and effectively turn back the clock. In The Telomere Miracle, he explains cutting-edge science in a lively style, using illustrations and metaphors ranging from auto parts to superheroes. Then he shows readers how they can intervene in the aging process by boosting the activity of the enzyme telomerase naturally by understanding and optimizing six key areas of breathing, mindset, sleep, exercise, diet, and supplements.
Telomere Territory and Cancer
by Parvin MehdipourTiming, racing, combating, struggling and targeting are some actions through which cellular fate could be reflected and evaluated. Interaction between cell territory and environment occur during pre-embryonic, fetal development, and post-natal periods. What the researchers observe as the outcome of telomeres behavior is only the peak of an ice mountain within a stormy ocean. Cellular life depends on programmed behavior of telomeres, capable to surprise the cells. Telomeres provide an introduction to the history of our cells which govern the quality of life and status of health. Telomeres as the cooperative territory are capable of stabilizing the chromosomal territory. The status of telomeres reflects the key information, announcing the real age of individuals, and may be a valuable marker for prognosis and predicting cancer. Telomere territory is characterized with a multi-disciplinary manner. Therefore, this book is aimed to offer a wide range of chapters, hoping to be useful for diverse audiences, including hematologists-oncologists, radiotherapists, surgeons, cancer researchers, and all the sectors who affect the macro- and micro- environmental domains. Finally, telomeres are sensitive, cooperative, and trustable targets. It is worth to state that 'telomeres are messengers of NATURE', let's to know them as they are.
Telomeres: Chromosome Sentinels
by Carole SaintoméTelomeres are specialized DNA–protein structures that protect the ends of chromosomes to maintain their integrity. They are chromosome sentinels. This book, written by multiple authors, presents current knowledge and the most recent discoveries relating to telomeres. The first chapters describe telomere structures (DNA and proteins), organization, dynamics and replication in a range of organisms including ciliates, yeast and mammals. The following chapters cover mechanisms that maintain telomere length involving telomerase and Alternative Lengthening Telomeres (ALT) mechanisms. Interestingly, telomeres are transcribed into repetitive RNA called TERRA (Telomeric repeat-containing RNA), the state of the art regarding mammalian telomere transcripts is presented here. Two chapters are dedicated to the description of how telomere biology impacts the development of cancer and how their disfunctions induce telomeropathies (telomere biology disorders). Finally, the book ends with a chapter presenting telomere and telomerase targeting agents as potential anticancer agents, a promising therapeutic approach.
Telomeres and Telomerase
by Zhou SongyangNew and rapid advances in technology have equipped us with a variety of tools and platforms to ask fundamental questions of telomere regulation and have allowed investigators to carry out experiments using diverse model systems. For example, proteomic, genomic, and molecular approaches have afforded us unprecedented insight into the complex protein interaction networks at work on the telomere chromatin and the detailed information regarding telomere dynamics in response to stress or stimuli. Telomeres and Telomerase: Methods and Protocols, Second Edition builds upon the telomerase assays featured in the popular first edition to encompass many different assays that allow investigators to query the function of telomere proteins and the responses of the telomere DNA, including detailed examinations of biochemical, molecular, and proteomic approaches. Written in the highly successful Methods in Molecular Biology(tm) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Telomeres and Telomerase: Methods and Protocols, Second Edition serves as an ideal, up-to-date guide for investigators further pursing this vital field of study.
Telomeres and Telomerase
by Zhou SongyangNew and rapid advances in technology have equipped us with a variety of tools and platforms to ask fundamental questions of telomere regulation and have allowed investigators to carry out experiments using diverse model systems. For example, proteomic, genomic, and molecular approaches have afforded us unprecedented insight into the complex protein interaction networks at work on the telomere chromatin and the detailed information regarding telomere dynamics in response to stress or stimuli. Telomeres and Telomerase: Methods and Protocols, Second Edition builds upon the telomerase assays featured in the popular first edition to encompass many different assays that allow investigators to query the function of telomere proteins and the responses of the telomere DNA, including detailed examinations of biochemical, molecular, and proteomic approaches. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and expert tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Telomeres and Telomerase: Methods and Protocols, Second Edition serves as an ideal, up-to-date guide for investigators further pursing this vital field of study.
Telomeres and Telomerase
by Michael J. Thompson John A. DoubleJohn A. Double and Michael J. Thompson have collected a critically important series of novel and essential techniques for studying telomeres and telomerase. These readily reproducible methods provide cutting-edge tools to identify, measure, and analyze telomeres, to determine telomerase expression at the RNA level, to determine telomerase activity, and to detect potential modifiers of this activity. The techniques for assaying telomerase activity range from standard radiological TRAP assays to nonradioactive methods, from non PCR-based methods to techniques using real-time PCR. Telomeres and Telomerase: Methods and Protocols provides the core array of productive techniques needed today to develop telomerase inhibitors or diagnostic/prognostic telomerase markers.
Telomeres, Diet and Human Disease: Advances and Therapeutic Opportunities
by Amelia Marti Guillermo ZalbaThe maintenance of telomeres—repetitive sequences at the end of chromosome—is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book describes the advances in telomere research as it applies to human health and especially how lifestyle and dietary factors could modify the telomerase maintenance process. The book examines the mechanisms involved, the primary of which are oxidative stress and the role of sirtuins, and how they can be modified by dietary patterns such as Mediterranean diet.
Tempature-Programmed Reduction for Solid Materials Characterization (Chemical Industries)
by Alan JonesThis guide discusses the principles and theory of temperature-programmed reduction (TPR) used for sold materials characterization. It describes the recent trends, instrumentation needed, as well as the application of TPR in heterogeneous catalysis, materials science, and analytical chemistry.
Temperate and Boreal Rainforests of the World
by Dominick A. DellasalaTemperate rainforests are biogeographically unique. Compared to their tropical counterparts, temperate rainforests are rarer and are found disproportionately along coastlines. Because most temperate rainforests are marked by the intersection of marine, terrestrial, and freshwater systems, these rich ecotones are among the most productive regions on Earth. Globally, temperate rainforests store vast amounts of carbon, provide habitat for scores of rare and endemic species with ancient affinities, and sustain complex food-web dynamics. In spite of their global significance, however, protection levels for these ecosystems are far too low to sustain temperate rainforests under a rapidly changing global climate and ever expanding human footprint. Therefore, a global synthesis is needed to provide the latest ecological science and call attention to the conservation needs of temperate and boreal rainforests. A concerted effort to internationalize the plight of the world's temperate and boreal rainforests is underway around the globe; this book offers an essential (and heretofore missing) tool for that effort. DellaSala and his contributors tell a compelling story of the importance of temperate and boreal rainforests that includes some surprises (e.g., South Africa, Iran, Turkey, Japan, Russia). This volume provides a comprehensive reference from which to build a collective vision of their future.
Temperate and Subtropical Fruit Production
by David Jackson Michael Morley-Bunker John Palmer Peter Lyford David Mcneil R Chapman William Atkinson Graham Thiele Roy Edwards David Penman Norman LooneyEffective fruit production requires general knowledge of fruit husbandry such as nutrition, propagation, pruning and training, effects of climate and crop protection as well as specific cultivation techniques for each fruit. Fully revised and expanded to include organic fruit production, this new edition provides a thorough introduction to the cultivation of fruit found throughout the temperate and subtropical regions of the world.
Temperate and Subtropical Fruit Production
by David Penman R Chapman Peter Lyford William Atkinson Roy Edwards John Palmer David McNeilFully revised and expanded to include organic fruit production, this new edition provides a thorough introduction to the cultivation of fruit found throughout the temperate and subtropical regions of the world.
Temperate Garden Plant Families: The Essential Guide to Identification and Classification
by Peter Goldblatt John C. ManningLearn how to identify the most important temperate plant families Based on the most up-to-date research, Temperate Garden Plant Families spans the spectrum from Acanthaceae (the acanthus family) to Zingiberaceae (the ginger family), and reflects the current scientific consensus about the family status of the most popular garden genera. Introductory information includes an overview of family classification, plant nomenclature, and plant morphology. The comprehensive A–Z of plants includes profiles that include information on the number of species and genera, plant form, flowers, fruit, and a short description. Each profile is illustrated with color photographs and botanical illustrations. Botanists, horticulturists, gardeners, and students will all welcome this authoritative yet accessible reference.
Temperate Nuts
by Shabir Ahmad Mir Mohammad Maqbool Mir Umar Iqbal Munib Ur RehmanThis book focuses on the production technology of temperate nuts. It explores cultivar and plant improvement, development and selection of rootstocks, plant–water relations and irrigation, canopy architecture, and postharvest packaging of nut fruits. It also deals with organic approaches, biotechnological interventions, diseases, and pest management. Contributing authors address nut fruits such as walnut, pecan nut, chestnut, and hazel nut on different recent aspects. The development achieved in the fruit sector is indicative of the fact that there is growing demand of fruit produce. Temperate nuts with health benefits and market acceptability have best sources of fat, fiber, protein, and mineral. They provide dietary fiber, potassium, and a variety of health-protective bioactive compounds. Apart from the health benefits, production of temperate nuts improves the economy of the country as these are very good source of income and employment. In addition, there is wide diversification in the production pattern of nuts globally. Increased production technology such as hybrids, high-yielding selections/ varieties, improved propagation techniques, and increased use of fertilizers and manures have brought spectacular increase in the production of nut fruits. This book is of interest to teachers, scientists, researchers, and scholars. Also, the book serves as additional reading material for undergraduate and postgraduate students of agriculture and horticulture. Horticulture nurseries and orchard industries also find this to be a useful read.
Temperatur und Wärme – was ist das wirklich?: Ein Überblick über die Definitionen in der Thermodynamik (essentials)
by Klaus StierstadtDieses essential vermittelt eine Einführung in die Thermodynamik und ermöglicht auch Einsteigern ein Verständnis der Thematik, welche eine Voraussetzung für die moderne Physik, die Chemie, Biologie und Technik ist. Der Schwerpunkt liegt auf den Grundlagen und aktuellen Fragestellungen. Das Buch schlägt eine Brücke zwischen den beiden Thermodynamik-Vorlesungen: der einfachen Wärmelehre im 1. oder 2. Semester und der anspruchsvollen Statistischen Physik im 5. Semester. Was Sie in der Zwischenzeit vergessen haben, oder was im 5. Semester vorausgesetzt wird, das finden Sie in diesem essential.
Temperature: Heating Up and Cooling Down
by Darlene R. Stille Sheree BoydAn interesting book on temperature with its characteristics and facts illustrated with examples in the form of activities.
Temperature and Humidity Independent Control (THIC) of Air-conditioning System
by Xiaohua Liu Yi Jiang Tao ZhangTemperature and Humidity Independent Control (THIC) of Air-conditioning System focuses on temperature and humidity independent control (THIC) systems, which represents a new concept and new approach for indoor environmental control. This book presents the main components of the THIC systems, including dehumidification devices, high-temperature cooling devices and indoor terminal devices. Other relevant issues, such as operation and control strategy and case studies, are also included. This book is intended for air-conditioning system designers and engineers as well as researchers working with indoor environments. Xiaohua Liu is an associate professor at the Building Energy Research Center, Tsinghua University, China. Yi Jiang is a member of the Chinese Academy of Engineering, the director of the Building Energy Research Center, Tsinghua University, China and the director of the China-USA Joint Research Center on Clean Energy. Tao Zhang is a Ph. D. candidate at the Building Energy Research Center, Tsinghua University, China.
Temperature and Plant Development
by Keara Franklin Philip WiggePlants are incredibly sensitive to changes in temperature. Changes of a single degree or two in ambient temperature can impact plant architecture, developmental processes, immune response, and plant reproduction. Temperature and Plant Development thoroughly explores plant molecular responses to changes in temperature with aim to understanding how plants perceive, integrate, and respond to temperature signals.Temperature and Plant Development explores the diverse molecular responses that plants exhibit as they face changing temperatures. Temperature-related changes and adaptations to essential developmental processes, such as germination, flowering, and reproduction, are explored in detail. Chapters also explore the impact of temperature on plant immune responses and the impact of rising temperatures on global food security.A timely and important book, Temperature and Plant Development will be a valuable resource for plant biologists, crop scientists, and advanced students.* Up-to-date and comprehensive coverage of the role of temperature on plant development.* Looks at changes and adaptations to plant developmental processes made in response to changing temperatures.* Explores the role of temperature on plant immune response and pathogen defense* Provides a timely look at the impact of changing temperatures on global food security
Temperature and Toxicology: An Integrative, Comparative, and Environmental Approach
by Christopher J. GordonThermoregulation is vital for survival but the interplay between toxic insults and thermoregulatory mechanisms is often poorly understood. Temperature and Toxicology: An Integrative, Comparative, and Environmental Approach is the first major text to study the integrative thermoregulatory responses of mammals that are exposed to toxicants. Because e
Temperature Measurement
by Bela G. LiptakTemperature Measurement covers nearly every type of temperature measurement device, in particular, bimetallic thermometers, filled bulb and glass stem thermometers, thermistors, thermocouples, and thermowells. Includes suppliers and prices.Béla G. Lipták speaks on Post-Oil Energy Technology on the AT&T Tech Channel.
Temperature-Programmed Gas Chromatography
by Leonid M. BlumbergThis book provides a comprehensive up-to-date overview of temperature-programmed gas chromatography (GC). The first part of the book introduces the reader to the basics concepts of GC, as well as the key properties of GC columns. The second part describes the mathematical and physical background of GC. In the third part, different aspects in the formation of a chromatogram are discussed, including retention times, peak spacing and peak widths. An invaluable reference for any chromatographer and analytical chemist, it provides all the answers to questions like:* At what temperature does a solute elute in a temperature-programmed analysis? * What is the value of the retention factor of eluting solute? * How wide are the peaks? * How large is the time distance between two peaks? * How do all these parameters depend on the heating rate?
Temperature-Responsive Polymers: Chemistry, Properties, and Applications
by Vitaliy V. Khutoryanskiy Theoni K. GeorgiouAn authoritative resource that offers an understanding of the chemistry, properties and applications of temperature-responsive polymers With contributions from a distinguished panel of experts, Temperature-Responsive Polymers puts the focus on hydrophilic polymers capable of changing their physicochemical properties in response to changes in environmental temperature. The contributors review the chemistry of these systems, and discuss a variety of synthetic approaches for preparation of temperature-responsive polymers, physicochemical methods of their characterisation and potential applications in biomedical areas. The text reviews a wide-variety of topics including: The characterisation of temperature-responsive polymers; Infrared and Raman spectroscopy; Applications of temperature-responsive polymers grafted onto solid core nanoparticles; and much more. The contributors also explore how temperature-responsive polymers can be used in the biomedical field for applications such as tissue engineering. This important resource: Offers an important synthesis of the current research on temperature-responsive polymers Covers the chemistry, the synthetic approaches for presentation and the physiochemical method of temperature-responsive polymers Includes a review of the fundamental characteristics of temperature-responsive polymers Explores many of the potential applications in biomedical science, including drug delivery and gene therapy Written for polymer scientists in both academia and industry as well as postgraduate students working in the area of stimuli-responsive materials, this vital text offers an exploration of the chemistry, properties and current applications of temperature-responsive polymers.
Temperature Sensitivity In Insects And Application In Integrated Pest Management
by Guy J Hallman David L DenlingerThis book focuses on an array of integrated pest management tools (IPM) that exploit extreme temperatures, examining the biological basis for using temperature extremes in controlling insects and presenting practical IPM techniques that rely on temperature.
Tempestade de Areia
by Michael R. SternComo se diz não para o Presidente dos Estados Unidos quando ele lhe pede para parar uma guerra nuclear? Depois que Fritz Russell descobriu que a porta da sua sala de aulas era um portal através do espaço e do tempo, ele ajudou os Estados Unidos a resolver uma emergência na política internacional. Agora o presidente quer que ele use o portal para evitar a ameaça vinda de uma nação do Oriente Médio, que está prestes a desenvolver armas nucleares.