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Textbook of Ion Channels Volume II: Properties, Function, and Pharmacology of the Superfamilies
by Jie Zheng and Matthew C. TrudeauThe Textbook of Ion Channels is a set of three volumes that provides a wide-ranging refer- ence source on ion channels for students, instructors and researchers. Ion channels are membrane proteins that control the electrical properties of neurons and cardiac cells; mediate the detection and response to sensory stimuli like light, sound, odor, and taste; and regulate the response to physical stimuli like temperature and pressure. In non-excit- able tissues, ion channels are instrumental for the regulation of basic salt balance that is critical for homeostasis. Ion channels are located at the surface membrane of cells, giving them the unique ability to communicate with the environment, as well as the membrane of intracellular organelles, allowing them to regulate internal homeostasis. Ion channels are fundamentally important for human health and diseases, and are important targets for pharmaceuticals in mental illness, heart disease, anesthesia, pain and other clinical appli- cations. The modern methods used in their study are powerful and diverse, ranging from single ion-channel measurement techniques to models of ion channel diseases in animals, and human clinical trials for ion channel drugs. Volume II starts with ion channel taxonomy and features coverage of major ion channel families, and describes the physiological role, structural components, gating mechanisms and biophysics, permeation and selectivity, regulation, pharmacology, and roles in dis- ease mechanisms. Channels in this volume include voltage-activated sodium, calcium and potassium channels, inward-rectifier and two-pore domain potassium channels, calcium- activated potassium channels, cyclic nucleotide-gated channels, pacemaker ion channels, chloride channels, ligand-gated receptors activated by acetylcholine, glutamate, 5-HT3, GABA and glycine, acid-sensing channels, P2X receptors, TRP channels, store-operated channels, pressure-activated piezo channels, ryanodine receptors, and proton channels. All three volumes give the reader an introduction to fundamental concepts needed to understand the mechanism of ion channels; a guide to the technical aspects of ion channel research; offer a modern guide to the properties of major ion channel families; and include coverage of key examples of regulatory, physiological and disease roles for ion channels.
Textbook of Ion Channels Volume III: Regulation, Physiology, and Diseases
by Jie Zheng and Matthew C. TrudeauThe Textbook of Ion Channels is a set of three volumes that provides a wide-ranging reference source on ion channels for students, instructors and researchers. Ion channels are mem- brane proteins that control the electrical properties of neurons and cardiac cells; medi- ate the detection and response to sensory stimuli like light, sound, odor, and taste; and regulate the response to physical stimuli like temperature and pressure. In non-excitable tissues, ion channels are instrumental for the regulation of basic salt balance that is critical for homeostasis. Ion channels are located at the surface membrane of cells, giving them the unique ability to communicate with the environment, as well as the membrane of intracellular organelles, allowing them to regulate internal homeostasis. Ion channels are fundamentally important for human health and diseases, and are important targets for pharmaceuticals in mental illness, heart disease, anesthesia, pain and other clinical appli- cations. The modern methods used in their study are powerful and diverse, ranging from single ion-channel measurement techniques to models of ion channel diseases in animals, and human clinical trials for ion channel drugs. Volume III includes coverage of key ion channel regulators and their mechanisms, the role of ion channels working in concert in selected physiological systems, and examples of ion channel mutations and dysfunction in a selection of diseases. Chapters on ion channel regulation include splice variants, calcium–calmodulin regulation, regulation by G pro- teins, and lipids. A selection of ion channels in physiological systems includes ion chan- nels of the heart, ion channels in immune cells and their role in pancreatic beta cells and regulation of insulin secretion, and the role of channels in sperm and eggs. While disease mechanisms are integrated into the chapters of Volume II, Volume III offers special consid- eration of ion channels in epilepsy, cystic fibrosis and pain syndromes. All three volumes give the reader an introduction to fundamental concepts needed to understand the mechanism of ion channels, a guide to the technical aspects of ion channel research, offer a modern guide to the properties of major ion channel families, and includecoverage of key examples of regulatory, physiological, and disease roles for ion channels.
Textbook of Mechanical Vibrations
by Mahesh Chandra LuintelThis textbook covers the fundamentals and applications of mechanical vibrations and is useful for both undergraduate and postgraduate courses. It provides a concise and clear presentation of dynamics and vibrations including many examples to provide instant illustration and applications of the mathematical relations obtained. It contains self-explanatory sketches, graphs, and figures to curtail long text. Numerous illustrated examples, exercises, and problems at the end of each chapter serve as good sources to grasp the basic principles presented in the text. Review questions and sufficient problems have also been included at the end of each chapter with answer keys for self evaluation. This textbook can also be used as a reference book by researchers and professionals interested in vibrations.
Textbook of Medical-Surgical Nursing (Thirteenth Edition)
by Janice L. Hinkle Kerry H. CheeverPrepare for medical-surgical nursing practice and success on the NCLEX with Brunner & Suddarth's Textbook of Medical-Surgical Nursing, 13th Edition. A favorite resource for students and practicing nurses for almost a half-century, this book provides comprehensive yet accessible coverage of a broad range of medical conditions while focusing on the nursing process and the nurse's role in caring for and educating patients and families within today's complex health care delivery system. Up-to-date coverage of the health care needs of people with disabilities, nursing research findings, ethical considerations, and evidence-based practice gives you opportunities to refine your clinical decision-making skills. Fully updated and enhanced, this new edition provides a fully integrated solution that promotes clinical judgment, performance, and success on the NCLEX examination and in nursing practice. Key Features in the 13th Edition: NEW! Concept Mastery Alerts clarify difficult concepts, informed by data from Misconception Alert questions in PrepU for Brunner & Suddarth's Textbook of Medical-Surgical Nursing, 12e. NEW! Quality and Safety Nursing Alerts build upon previous edition's Nursing Alerts to highlight issues related to quality and safety nursing care. NEW! The updated unit openers include new Case Studies with QSEN Competency Focus to highlight a competency and related knowledge, skills, and attitudes. Additional information for these case studies related to NANDA-I, NIC, NOC and the nursing process is available online. NEW! Prioritization Questions have been added to the Critical Thinking Exercises. UPDATED! Genetics Charts and Ethical Dilemma Charts have been revised to reflect the latest advances in the field. UPDATED! Critical care information has been updated to further the authors' goal to have the most up-to-date and clinically relevant content on critical care throughout the book. EXPANDED! Expanded coverage of obesity, highlighted with a new icon, focuses on this epidemic health problem in our society. STEAMLINED! The Table of Contents has been reorganized for a more logical sequence and flow. REVISED! The accompanying Study Guide now features reorganized content and revised questions. Nursing Process sections, Plans of Nursing Care, and Critical Care sections More than 2,900 NCLEX-style review questions Assessment Charts, Risk Factor Charts, Guidelines Charts, Genetics in Nursing Practice Charts, Patient Education Charts, Health Promotion Charts, Ethics and Related Issues Charts, and Pharmacology Charts and tables. Gerontologic Considerations sections, Physiology/Pathophysiology figures, and Home Care Checklists Nursing Research Profiles and EBP questions help students learn the importance of evidence-based practice. Concepts in Action Animations bring anatomy, physiology and pathophysiology concepts to life.
Textbook of Membrane Biology
by Rashmi Wardhan Padmshree MudgalThis book provides a comprehensive overview of the basic principles, concepts, techniques and latest advances in the field of biomembranes and membrane-associated processes. With new emerging technologies and bioinformatics tools, this is a promising area for future study and research. The book discusses the composition, fluidity and dynamic nature of phospholipid bilayers, which vary with cell/organelle type and function. It describes the various types of transport proteins that facilitate the transport of polar and nonpolar molecules across the membrane actively or passively via ion-channels or through porins. It also explores the many cellular functions membranes participate in: (1) energy transduction, which includes the electron transport chain in inner membrane of mitochondria and bacterial cytoplasmic membrane and photosynthetic electron transport in thylakoid membranes in chloroplast and photosynthetic bacterial membranes; (2) cell-cell communication involving various signal transduction pathways triggered by activated membrane receptors; (3) cell-cell interactions involving various types of adhesion and receptor proteins; (4) nerve transmission involving opening and closing of voltage gated ionic channels; and (5) intracellular transport involving the processes of endocytosis, exocytosis, vesicular transport of solutes between intracellular compartments, membrane fusion and membrane biogenesis.
Textbook of Microbiology and Immunology
by Subhash Chandra ParijaThe fourth edition of “Textbook of Microbiology and Immunology” is an extensively revised edition , a healthy mixture of the old and the new contents. Many of the old traditional chapters have been retained with addition of new information along with the inclusion of new chapters more in line with the on-going changes in the syllabus and concepts in Medical Microbiology .While doing so, this book has blended the traditional organism-based learning and a syndrome based approach to infectious disease, together with the introduction of new and modified chapters incorporating the latest information in this field.The book provides an extensive coverage of fundamental topics in general and medical microbiology. The book also lays due emphasis on clinical microbiology with special focus on syndrome based approach to infectious diseases. It includes the basic concepts of microbiology as well as the recent updates and developments in the field of medical microbiology. All the topics have been incorporated in seven major sections: General microbiology, Immunology, Bacteriology, Virology, Mycology, and Applied and Clinical Microbiology.The dynamic nature of medical sciences with new guidelines and new diagnostic methods coming into the arena necessitates the incorporation of new information in each new edition of a book. This facet has been addressed with the inclusion of recent information on the various aspects of microbiology, infectious diseases and immunology, in the fourth edition of the Textbook of Microbiology and Immunology ,which makes it one of the most authoritative and informative textbooks in medical microbiology.The book is an effort to inform and engage a wide spectrum of readers including medical students , both undergraduates and postgraduates, and residents, and faculty. It aims to be a must-have companion book for graduate and advanced undergraduate as well as postgraduate students of medical microbiology, general and allied microbiology, and of immunology.
A Textbook of Modern Toxicology
by Ernest HodgsonA Textbook of Modern Toxicology is a unique resource that provides both students and practitioners with a wide-ranging, accessible overview of the discipline. Suitable for courses in environmental, pharmacological, medical, and veterinary toxicology, this essential text features chapters written by experts who address a range of key topics.The Fourth Edition includes additional chapters on new approaches to toxicology - molecular methods (-omics: toxicogenomics, proteomics, and metabolomics), bioinformatics, and systems biology - and continues the legacy of its predecessors to provide up-to-date insights into acute toxicity and chemical carcinogenesis, organ toxicity, in vitro and in vivo toxicity testing, ecological risk assessment, and many other areas of toxicology that help foster a solid comprehension of the field.Also featured in the Fourth Edition are end-of-chapter questions and a Solutions Manual available separately for academic adopters.
The Textbook of Nanoneuroscience and Nanoneurosurgery
by Babak Kateb John D. Heiss John S. Yu Ming HsiehThis textbook highlights the exciting field of nanoneuroscience and its potential to transform how we diagnose and treat neurological disorders. "The Textbook of Nanoneuroscience and Nanoneurosurgery," dives deep into this emerging field, exploring the latest tools and techniques currently being developed at the nanoscale level. Key areas of focus include: Nanoplatforms: The book explores how scientists utilize materials on a near-microscopic scale for neurosurgery, neurology, and brain imaging applications. Bridging the Gap: Regulatory hurdles for translating research from the lab to real-world use are addressed, paving the way for future advancements. The Future is Now: The book showcases recent breakthroughs already impacting patient care alongside promising areas with significant potential. Collaboration is Key: Insights from over 220 researchers and 5000+ references, along with illustrative figures in B/W and color, provide a comprehensive overview of this dynamic field. With its focus on minimally invasive procedures and the latest regulatory considerations， "The Textbook of Nanoneuroscience and Nanoneurosurgery" equips researchers and medical professionals with the knowledge to develop groundbreaking treatments for neurological conditions. The text also reviews the latest regulatory guidelines that influence the translation of nanotechnological research from the laboratory to the clinic and the most recent information on biodevices and pharmaceutical spinoffs. It highlights presidential and congressional initiatives and programs that may impact the field soon. Some reviews of the First edition of the textbook. "…a significant contribution to the field of nanoneuroscience and nanoneurosurgery … the reader will come away with a deeper understanding of the history of nanotechnology and medicine." —Neuroscience "This is a monumental first textbook on nanoneurosurgery. … recommended reading for neurosurgeons, neurologists, neuroradiologists, and neuroscientists involved in research on new techniques for application in neurosurgery. Biomedical engineers and various companies developing instruments and devices would benefit from the wealth of information about trends for the development of new technologies for neurosurgery." K. K. Jain, MD, Basel, Switzerland "Phenomenal body of knowledge in this book that would take eons to collate by myself. Every answer to every one of my questions plus heaps more. Essential reading for everyone interested in the field. A must-have!" Albert Deme "This is an amazing foray into the future of a largely unexplored, but increasingly critical medical domain…..I have learned much from every page of this captivating text, and I highly recommend it to any medical student, researcher, medical professional in the neurosciences, or anyone who has an interest in the human brain and the future of medicine, to gather a glimpse of the incredible and beneficial paradigm shifts that will soon impact the field of neuroscience." Frank Boehm, British Columbia, Canada
Textbook of Neurointensive Care
by A. Joseph Layon Andrea Gabrielli William A. FriedmanThis updated and refined new edition is the only book to provide a comprehensive approach to the intensive care of neurologically injured patients from the emergency room and ICU through the operating room and post-surgical period. It reviews neuroanatomy, neuroradiology, and neurophysiology, examines the neurological problems most frequently seen in intensive care, and describes the various types of neurosurgery. General issues are discussed, such as cardiac care, fluids and electrolytes, nutrition, and monitoring as well as more specific conditions and complications including elevated intracranial pressure, seizures, and altered mental states.
Textbook of Nutrition in Health and Disease
by Kaveri Chakrabarty A. S. ChakrabartyThis textbook offers a concise, yet comprehensive account of human nutrition, food and nutrition-related health problems, based on the curricula of top universities around the globe. Nutrition is a multidisciplinary science, and as such, the book discusses various aspects of physiology, biochemistry, pathology, immunology, medicine, food science, and other fields related to nutrition, it focuses on the role of nutrition in the maintenance of health. The various chapters explore highly relevant issues, such as, addiction-related health problems, lifestyle-related disorders, social health problems and poor-maintenance of food hygiene and food safety. It also addresses the role of nutritional therapies for mental disorders, and includes an integrated perspective on cognition, oxidative stress and nutritional interventions in aging. Other topics include, the role of gut microbiota on human health, nutraceuticals as therapeutic agents and ketogenic diets. It also highlights malnutrition (protein energy malnutrition, starvation, malabsorption syndrome, eating disorders and overnutrition/obesity) and adipose tissue as an active endocrine organ. Moreover, it examines key concepts concerning the role of vitamins in the citric acid cycle (gluconeogenesis, ketogenesis, oxidative deamination and transamination) and precursors of coenzymes, as well as calorigenic hormones, appetite-stimulating/appetite-inhibiting hormones, anabolic and catabolic hormones affecting protein metabolism, and lipogenetic/lipolytic hormones.
Textbook of Nutritional Biochemistry
by Darshan Malik Nandita Narayanasamy V A Pratyusha Jayita Thakur Nimisha SinhaThis textbook for undergraduate students aims at providing an in-depth understanding of the relationship between diet, nutrients, health, diseases, and drug treatment. The book presents a comprehensive but detailed view of the field of Nutritional Biochemistry; balancing the historical with contemporary findings, the descriptive with the experimental, structure with function as well as the mechanistic and the clinical aspects of any particular nutrient. Though the major emphasis of the book is on Nutritional Biochemistry, the book also attempts to provide an insight into other related and relevant areas. Amongst the topics that are covered are: nutraceuticals, food, and nutrient interactions; the newly emerging field of the human microbiome, its interdependence on diet and human health as well as the public health concerns which is a looming burden of non-communicable diseases. Each chapter begins with an insight into the history of discovery and structure of the nutrient, its absorption, and metabolism, physiological functions, ending with diseases associated with nutrient deficiency/toxicity along with a clinical perspective. Apart from this, the book emphasizes the biochemical basis of physiological responses and correlates the same with symptoms identifying the pathophysiology. This textbook caters to students of undergraduate courses like Biochemistry, Biomedical Sciences, Biological Sciences, Life Sciences, Home Science; Nutrition and Dietetics, Clinical Nutrition and Dietetics, and Nursing.
A Textbook of Optics
by Suresh Chandra Mohit Kumar SharmaThis book is designed to serve as a textbook for courses offered to upper-undergraduate students enrolled in physics and explains the broad spectrum of optics in a student-friendly way. The textbook covers the entire syllabi of the undergraduate courses being taught at both national and international universities including adequate details of mathematical expressions to help students understand the subject matter. The topics covered in this book are reflection, refraction, cardinal points, interference, Fresnel diffraction, Fraunhofer diffraction, lasers and holography, fiber optics, etc. This book explains each topic in a simple and lucid language with the help of solved problems. Exercises with multiple choice questions have been given at the end of each chapter for self-assessment. The detailed coverage and pedagogical tools make this an ideal textbook for students and researchers enrolled in senior undergraduate and beginning postgraduate physics students.
Textbook of Oxidative Stress and Antioxidant Protection
by Donald Armstrong Robert D. StrattonOxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease provides an overview of the basic principles of free radical formation. The text delves into free radical formation in molecular biology and its effect on subcellular damage, as well as the role of antioxidant reserves as a protective mechanism. Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.
Textbook of parasitic zoonoses (Microbial Zoonoses)
by Subhash Chandra Parija Abhijit ChaudhuryThis textbook, which is the first volume in the series Microbial Zoonoses, provides a comprehensive overview of the diagnosis, treatment and control of zoonotic parasitic diseases. The book is divided into two sections; the first section discusses the classification of parasitic zoonoses and includes general information on the diagnosis, treatment, epidemiology, prevention, and control of parasitic zoonoses. It also describes the biological features of these organisms, host-parasite interactions, and the disease spectrum, as well as the importance of public health control measures, such as surveillance, and prophylactic measures in controlling these diseases.The second section explores the important zoonotic diseases caused by ectoparasites, protozoan and helminths parasites. It also reviews the life cycle, pathogenesis, pathology, immunology and clinical manifestations, modern diagnostic methods, treatment regimen, prevention, control, and epidemiology of these parasites.Cutting across the disciplines, this book serves as a guide to postgraduate students, faculty members, public health experts, and medical administrators who are interested in the management of these parasitic zoonotic infections.
Textbook of Pathologic Anatomy: For Medical Students
by Kuisheng Chen Li Liang Mincai Li Yun PanThis book introduces the basic knowledge about pathologic anatomy, which covers the the etiology, pathogenesis, pathological changes and outcomes of diseases. It will help the student to understand and master the nature of various diseases and the theories in occurrence and development.This book consists of 18 chapters, including 6 chapters in general pathology and 12 chapters in systematic anatomy. In each chapter, it starts from the most important ‘Key Concepts’ to learn, which will guide the student during the learning stage and review stage.This book is a useful textbook for graduate and undergraduate students in medical schools, including MBBS (Bachelor of Medicine and Bachelor of Surgery) student.
Textbook of Personalized Medicine
by Kewal K. JainPersonalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing personalized medicine. Basic technologies for personalized medicine, of which molecular diagnostics has the biggest share, are mentioned briefly and appropriate references are given for further information. Commercial aspects are discussed briefly in a chapter and detailed analysis of markets and companies involved in personalized medicine is presented in a special report on this topic. There is increasing interest in personalized medicine. Considerable advances have taken place in molecular biology and biotechnology to make personalized medicine a viable option, but some misconceptions still exist, both in the academic and commercial sectors. There is lack of a suitable source of information that provides both the fundamentals as well as applications of personalized medicine. As the latest version of the first monograph on personalized medicine published in 1998, this volume, Textbook of Personalized Medicine, summarizes the author's efforts during the past decade, as well as reviews selected studies done during this period in a readable format for the physicians and scientists. It is hoped that physicians, pharmacists, scientists and interested lay readers with basic scientific knowledge will find this book useful.
Textbook of Real-Time Three Dimensional Echocardiography
by Roberto M. Lang Luigi Badano Jose Luis ZamoranoThis Textbook will give the reader a detailed understanding of the use of 3D echo covering a wide range of topics; from the evolution of RT3D echo to the role of RT3D echo in drug trials, including chapters on the Principles of Transthoracic and Transesophageal Real-time 3D echocardiography. Other books in this area are more varied, less specific.
Textbook of Receptor Pharmacology
by John C. Foreman Torben Johansen Alasdair J. GibbFor the past four decades, University College London has offered a renowned course on receptor pharmacology. Originating from a renowned course on receptor pharmacology, this text presents in-depth coverage of this rapidly expanding research area. The book combines current understanding of classical quantitative pharmacology and drug-receptor interactions with the basics of receptor structure and signal transduction mechanisms. It focuses on molecular investigation of receptor structure, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction at the cell membrane. This edition includes updated chapters on receptor structure and signal transduction by G-proteins and tyrosine kinases as well as enhancements to the quantitative treatment of drug-receptor interactions. Several chapters contain problems and worked-out solutions.
Textbook of Robotic Liver Surgery
by Mathieu D’Hondt Iswanto SucandyAfter an initial slow diffusion of minimal invasive approaches in liver surgery, laparoscopy has now been implemented worldwide. This process has been sped up after several papers showed the superiority of laparoscopy over the open approach with regard to short-term outcomes. Before, the adaptation and diffusion of LLS was much slower compared to other general surgical specialties. The challenge in controlling major hemorrhage, the risk of gas embolism, the steepness of the learning curve and the uncertainty about oncological outcomes were barriers for the implementation of LLS. Nowadays, laparoscopic liver resections (LLR) are considered safe and feasible. The same evolution is seen in the diffusion of robotic liver surgery (RLS). The first reported robotic liver resection was published in 2003. Introduction of RLS has remained very slow compared to other subspecialties. This could be attributed to the complexity of minimally invasive liver surgery and the steep learning curve to overcome. Furthermore, the absence of instruments for parenchyma transection appeared to be a barrier for many surgeons to start RLS. Nowadays, Robotic liver surgery is in it's pioneering phase and limited to a few high volume centers. Furthermore data regarding the implementation of RLS are still scarce and the reproducibility of the implementation is still debated. This textbook will offer readers a useful overview of RLS state of the art, collecting the contributions of renowned robotic liver surgeons from Europe, Asia and the Americas. The editors will collaborate with a professional medical illustrator specialized in minimal invasive liver surgery to offer readers a visual experience of the most important surgical steps.
Textbook of Seismic Design: Structures, Piping Systems, and Components
by G. R. Reddy Hari Prasad Muruva Ajit Kumar VermaThis book focuses on the seismic design of Structures, Piping Systems and Components (SSC). It explains the basic mechanisms of earthquakes, generation of design basis ground motion, and fundamentals of structural dynamics; further, it delves into geotechnical aspects related to the earthquake design, analysis of multi degree-of-freedom systems, and seismic design of RC structures and steel structures. The book discusses the design of components and piping systems located at the ground level as well as at different floor levels of the structure. It also covers anchorage design of component and piping system, and provides an introduction to retrofitting, seismic response control including seismic base isolation, and testing of SSCs. The book is written in an easy-to-understand way, with review questions, case studies and detailed examples on each topic. This educational approach makes the book useful in both classrooms and professional training courses for students, researchers, and professionals alike.
Textbook of Stereotactic and Functional Neurosurgery
by Philip L. Gildenberg Ronald R. Tasker Andres M. LozanoThis volume covers stereotactic principles and functional stereotaxis. Amongst the stereotactic principles are discussions of frame-based and frameless systems of stereotaxis, image guidance stereotaxis, atlases and the technical aspects of radiosurgery. Within functional neurosurgery, disorders covered include the diagnosis and management of pain, epilepsy, movement disorders and the rediscovered field of surgery for psychiatric disorders.
Textbook of Three-Dimensional Echocardiography
by Luigi P. Badano Roberto M. Lang Denisa MuraruThis thoroughly revised textbook provides a practically applicable guide to three-dimensional echocardiography (3DE). Background is provided on the evolution of the technology and physics that support the implementation of both transthoracic and transesophageal approaches to 3DE. The incremental value of 3DE to assess cardiac chambers is also described. Moreover, a range of cardiac valvular diseases including the mitral, aortic, and tricuspid valve have been portrayed and illustrated in depth.These include congenital abnormalities, regurgitation and stenosis. Emphasis is also placed on technical aspects of the technique and where it can provide added value, including post-surgery assessments and evaluation of cardiac masses.Textbook of Three-Dimensional Echocardiography enables readers to develop a deep understanding of how to use this imaging modality. It provides a valuable resource for the echocardiography trainee looking to develop their knowledge and for the experienced practitioner seeking a comprehensive up-to-date reference.
Textbook of Vascular Medicine
by Rhian M. Touyz Christian DellesThis textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.
Textbook of Veterinary Parasitology
by S. C. MandalThis textbook for graduate students imparts knowledge on parasites of veterinary significance. It provides a basic understanding of taxonomy, morphology, life cycle, pathogenesis, diagnosis, treatment, and control strategies against important helminthic, protozoan and arthropod parasites of animals. The book also presents the useful information on the host-parasite interactions, host response, immune regulation, the impact of nutrition on the host immunity, and immune evasion by the parasite. This textbook is an essential reference for veterinary graduates, providing up-to-date resources on diagnosis, treatment, and controlling essential parasites of animals.
Textbook of Veterinary Physiology
by Pradip Kumar Das Veerasamy Sejian Joydip Mukherjee Dipak BanerjeeThis textbook explores the fundamental qualitative and quantitative aspects of veterinary physiology. It presents the morphological description of the organs, tissues, and cells involved in the physiological system with species variation. The book provide the most up-to-date information and in depth knowledge in animal physiology. The book addresses a broad range of topics, including the physiology of digestion in, monogastric animals, ruminants, and birds, and cardio vascular and respiratory system in different animals. The chapters contain a wealth of information on the areas related to the endocrine system, excretory system, body fluid homeostasis, hematology, male and female reproductive systems, coordination of body functions, and regulation of brain functions and sense organs. Further, this book acquaints students with advanced topics like immune system, assisted reproductive technology, ovarian dynamics, environmental physiology and thermoregulation, and behavioral physiology. This textbook contains clear illustrations including graphical abstracts and study questions for each chaptermaking this book a valuable learning resource for veterinary sciences and veterinary medicine students.Further to attract students and create interest in them, interesting facts related to animal physiology have also been highlighted in form of “Know more widges”.