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The Vascular Flora of the National Park of Abruzzo, Lazio and Molise (Central Italy)
by Fabio Conti Fabrizio BartolucciThis book provides an updated list of the vascular flora of the National Park of Abruzzo, Lazio and Molise, incorporating the latest nomenclatural and floristic findings. The list of plants was extrapolated from a geographic database including all data from floristic or vegetational references and herbarium specimens concerning the Park area. This data storage tool was obtained from the database of Abruzzo vascular flora (Conti et al. 2010) and adapted to the study area by adding those areas of the Park falling in the regions of Lazio and Molise and their accompanying floristic and vegetational data. Analysis of the data has allowed gaps in the floristic knowledge of the Park, such as comparatively or completely unexplored areas, to be identified, together with those species records that still require confirmation and/or further study. On the basis of these deductions, fieldwork aimed at the collection of new floristic data was carried out. Verification of the correct identification of herbarium specimens collected in the past, as well as a systematic study of critical genera, were also important priorities.
Vascular Hyperpermeability: Methods and Protocols (Methods in Molecular Biology #2711)
by Binu TharakanThis volume focuses on the latest research methods and techniques used by researchers to study vascular permeability/hyperpermeability in a science laboratory setting. The chapters in this book cover topics such as determination of solute permeability of microvascular endothelial cell monolayers in vitro; evaluation of barrier integrity used in a two-layered microfluidic device mimicking the blood-brain barrier; isolation and culture of human umbilical vein endothelial cells; measurement of blood-brain barrier hyperpermeability using Evans Blue extravasation assay; lymphatic vascular permeability determined from direct measurements of solute flux; intravital imaging of leukocyte-endothelial interaction by intravital multiphoton microscopy; and evaluation of tight junction integrity in brain endothelial cells using confocal microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and cutting-edge, Vascular Hyperpermeability: Methods and Protocols is a valuable resource that will aid novice researchers with creating new and affordable research projects, and for expert researchers to initiate new strategies and collaborations in their ongoing programs.
Vascular Interventional Radiology
by Mark G. CowlingThis new edition of Vascular Interventional Radiology: Current Evidence in Endovascular Surgery provides a thorough yet succinct and accessible review of the latest knowledge in the field of endovascular surgery. All chapters have been updated to reflect the advances that have occurred during the past five years, and new chapters are included on carotid artery stenting and day case intervention. The chapter on lower limb veno-occlusive disease has been expanded to include management of deep venous thrombosis. Among the other topics considered are the endovascular treatment options in different arterial territories, aneurysm repair techniques, and the management of venous stenosis and venous insufficiency. The aim throughout is to tackle issues of evidence-based practice in order to assist trainees and experienced practitioners in making and implementing treatment decisions. This book will be an invaluable source of information for both interventional radiologists and vascular surgeons with an interest in endovascular techniques.
Vascular Mechanobiology in Physiology and Disease (Cardiac and Vascular Biology #8)
by Markus Hecker Dirk J. DunckerThis volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiac mechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.
Vascular Morphogenesis: Methods and Protocols (Methods in Molecular Biology #2206)
by Domenico RibattiThis detailed new edition aims to provide a range of methods and protocols for studying vascular morphogenesis in vivo and in vitro to reflect up-to-date advances in the field. Of note, the book explores endothelial cell signaling is currently understood to promote fundamental cues for cell fate specification, embryo patterning, organ differentiation, and postnatal tissue remodeling. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and timely, Vascular Morphogenesis: Methods and Protocols, Second Edition will serve as an ideal guide to this area of study for a broad audience amongst cell biologists, anatomists, pathologists, and physiologists.
Vascular Organization of Angiosperms: A New Vision
by Jean-Pierre AndreThis study of plant anatomy is based on newly available data on the structure and spatial organization of the vascular system of plants. For the first time, by means of a new technique of intracellular moulding, the vascular system can be observed in its length. Many examples are chosen from among the major groups of the plant kingdom to illustrate
Vascular Plant Communities of Morocco: Phytosociology, Ecology And Geography (Geobotany Studies)
by Mohammed Sghir Taleb Mohamed FennaneThis book offers a comprehensive overview of the phytosociological information currently available in Morocco – a country famous for its floristic and landscape diversity. There has been little literature on the topic; however, in recent decades there have been a number of advances in the field of vegetation communities in the country, and several new phytosociological units have been described.
The Vascular Plant Communities of the Retezat National Park (Geobotany Studies)
by Gheorghe Coldea Vasile CristeaThe floristic studies carried out during the 19th and 20th centuries in the Retezat Massif identified 1,152 plant species and 104 subspecies within the Cormobionta sub-regnum. Of these, about 12% are endemic Carpathian and Dacian-Balkan taxa that induce a regional specificity to the hosting communities. The phytocoenological research led to the description of 67 plant associations, grouped in 28 alliances, 19 orders and 13 vegetation classes. These classes are: Asplenietea trichomanis, Thlaspietea rotundifolii, Salicetea herbaceae, Montio-Cardaminetea, Scheuchzerio-Caricetea fuscae, Oxycocco-Sphagnetea, Molinio-Arrhenatheretea, Caricetea curvulae, Loisleurio-Vaccinietea, Elyno-Seslerietea, Mulgedio-Aconitetea, Carpino-Fagetea and Vaccinio-Piceetea. The following plant associations herein described are new syntaxa: Phyteumo confusi-Junicetum trifidi, Salici kitaibelianae-Dryadetum octopetalae and Aconito taurici-Rumicetum alpine. For the protection of some rare plant species and vulnerable plant associations, two natural reserves are proposed to be created within the “Limestone Retezat” area.
Vascular Protection: Molecular Mechanisms, Novel Therapeutic Principles and Clinical Applications
by Gabor M. Rubanyi Victor J. Dzau John P. CookeVascular Protection explores advances in vascular biology and how they translate into innovations in drug therapy for vascular disease. It addresses recent advances in the knowledge of endothelial vasoactive factors and other biologically active molecules as well as gene therapy. Written by leading experts in their respective fields, each chapter e
Vascular Proteomics
by Fernando VivancoProteomics is a rapidly expanding investigation platform in cardiovascular medicine. Driven by major improvements in mass spectrometry (MS) instrumentation and data analysis, the proteomics field has flourished in recent years particularly in the study of complex diseases. These recent advances are characterized by the development of quantitative MS-based methods that promoted the field from primarily identifying proteins to also providing measurements of relative changes in protein levels between different cell states. This progress is reflected in the application of proteomic techniques to vascular pathology. Vascular Proteomics: Methods and Protocols provides up-to-date methods and protocols for the analysis of arteries, cells, lipoproteins, body fluids, and metabolites, with a particular focus on MS-based methods of protein and peptide quantification. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Vascular Proteomics: Methods and Protocols is a representative selection of methods that can be a useful resource for experienced proteomics practitioners as well as newcomers interested in becoming acquainted with the practice of proteomic techniques for cardiovascular research.
Vascular Surgery
by Jamal J. Hoballah Alan B. LumsdenVascular care has evolved from conservative therapy and open surgical therapy to a minimally invasive approach using endovascular techniques, laparoscopic or thoracoscopic techniques as well as hybrids of open and endovascular techniques. This volume provides up-to-the-minute information and details new developments and procedures.
Vascular Tissue Engineering: Methods and Protocols (Methods in Molecular Biology #2375)
by Feng Zhao Kam W. LeongThis volume explores the latest techniques used to study the field of tissue engineered vascular grafts (TEVGs). The chapters in this book cover a wide array of topics such as deriving vascular cells from monocytes and induced pluripotent stem cells; engineering vascular grafts using various biomaterials and stem cells, stem cell-derived, or primary vascular cells; biomaterial modification by anticoagulation molecules; vascular bioengineering technologies such as 3D bioprinting; and fabrication of TEVGs with different geometry and multiphase structures. This book also features protocols for grafting and evaluation of vascular grafts in animal models, vascular imaging in animals, and the quantification of blood vessel permeability. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vascular Tissue Engineering: Methods and Protocols is a valuable resource for biomedical engineers, cell biologists, vascular surgeons, doctors, and nurses.
Vascularization: Regenerative Medicine and Tissue Engineering
by Eric M. BreyA Complex and Growing FieldThe study of vascularization in tissue engineering and regenerative medicine (TERM) and its applications is an emerging field that could revolutionize medical approaches for organ and tissue replacement, reconstruction, and regeneration. Designed specifically for researchers in TERM fields, Vascularization: Regenerative M
Vasculogenic Mimicry: Methods and Protocols (Methods in Molecular Biology #2514)
by Emily Marques dos Reis Fernanda BertiThis volume provides detailed protocols for the identification and understanding of vasculogenic mimicry process in vitro and in vivo, in addition to protocols for microscopy and histology. Chapters guide readers through different materials, commercial and homemade scaffolds, Matrigel, cancer spheroids, 3D tissue constructs, vasculogenic processes, and mathematical model building. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Vasculogenic Mimicry: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Vasculopathies: Behavioral, Chemical, Environmental, and Genetic Factors (Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems #8)
by Marc ThirietThis volume presents one of the clinical foundations of vasculopathies: the biological markers and risk factors associated with cardiovascular disease. A detailed biological and clinical framework is provided as a prerequisite for adequate modeling. Chapter 1 presents cardiovascular risk factors and markers, where the search for new criteria is aimed at improving early detection of chronic diseases. The subsequent chapters focus on hypertension, which involves the kidney among other organs as well as many agents, hyperglycemia and diabetes, hyperlipidemias and obesity, and behavior. The last of these risk factors includes altered circadian rhythm, tobacco and alcohol consumption, physical inactivity, and diet. The volumes in this series present all of the data needed at various length scales for a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in anatomical conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning in quantitative terms.
Vaskuläre Biomechanik: Konzepte, Modelle und Anwendungen
by T. Christian GasserDieses Lehrbuch dient als moderne Einführung in die vaskuläre Biomechanik und bietet den umfassenden Überblick über das gesamte Gefäßsystem, der für die Durchführung erfolgreicher vaskulärer biomechanischer Simulationen erforderlich ist. Es zielt darauf ab, dem Leser eine ganzheitliche Analyse des Gefäßsystems in Richtung seiner biomechanischen Beschreibung zu vermitteln und enthält zahlreiche vollständig durchgerechnete Beispiele. Zu den verschiedenen behandelten Themen gehören die Beschreibung des Gefäßsystems, der Gefäßaustausch, die Mechanik der Blutgefäße, die Charakterisierung des Gefäßgewebes, die Mechanik des Blutflusses sowie das Wachstum und der Umbau des Gefäßgewebes.Dieses Lehrbuch ist ideal geeignet für Studenten und Forscher, die sich mit klassischer und rechnerischer vaskulärer Biomechanik beschäftigen. Das Buch könnte auch für Entwickler von vaskulären Geräten und für Experten, die sich mit der Zulassung biomedizinischer Simulationen befassen, von Interesse sein.Folgt dem Prinzip des "learning by doing" und bietet zahlreiche vollständig durchgerechnete Beispiele für aktives Lernen, sofortiges Erinnern und Selbstüberprüfung;Vermittelt ein ganzheitliches Verständnis der Funktionsweise von Gefäßen und die Integration von Informationen aus verschiedenen Disziplinen, um die Studierenden in die Lage zu versetzen, anspruchsvolle numerische Methoden zur Simulation der Reaktion des Gefäßsystems einzusetzen;Enthält mehrere Fallstudien, die das vorgestellte Material integrieren. Die Fallstudien befassen sich mit Problemen wie der biomechanischen Bewertung des Rupturrisikos von Bauchaortenaneurysmen, der Finite-Elemente-Analyse von Struktur- und Blutflussproblemen sowie der Berechnung von Wandspannung und Wandschubspannung in der Aorta.
Vaulting Ambition: Sociobiology and the Quest for Human Nature
by Philip KitcherVaulting Ambitionis the first extensive and detailed evaluation of the controversial claims that sociobiologists have made about human nature and human social behavior. It raises the "sociobiology debate" to a new level, moving beyond arguments about the politics of the various parties involved, the degree to which sociobiology assumes genetic determinism, or the falsifiability of the general theory. Sociobiology has made a great deal of noise in the popular intellectual culture. Vaulting Ambition cuts through the charges and counter-charges to take a hard look at the claims and analyses offered by the sociobiologists. It examines what the claims mean, how they relate to standard evolutionary theory, how the biological models are supposed to work, and what is wrong with the headline-grabbing proclamations of human sociobiology. In particular, it refutes the notions that humans are trapped by their evolutionary biology and history in endlessly repeating patterns of aggression, xenophobia, and deceitfulness, or that the inequities of sex, race, and class are genetically based or culturally determined. And it takes up issues of human altruism, freedom, and ethics as well. Kitcher weighs the evidence for sociobiology, for human sociobiology, and for "the pop sociobiological view" of human nature that has engendered the controversy. He concludes that in the field of nonhuman animal studies, rigorous and methodologically sound work about the social lives of insects, birds, and mammals has been done. But in applying the theories to human beings-where even more exacting standards of evidence are called for because of the potential social disaster inherent in adopting a working hypothesis as a basis for public policy - many of the same scientists become wildly speculative, building grand conclusions from what Kitcher shows to be shoddy analysis and flimsy argument. While it may be possible to develop a genuine science of human behavior based on evolutionary biology, genetics, cognition, and culture, Kitcher points out that the sociobiology that has been loudly advertised in the popular and intellectual press is not it. Pop sociobiology has in fact been felled by its overambitious and overreaching creators.
Vax-Unvax: Let the Science Speak (Children’s Health Defense)
by Robert F. Kennedy Jr. Brian HookerThe Studies the CDC Refuses to Do This book is based on over one hundred studies in the peer-reviewed literature that consider vaccinated versus unvaccinated populations. Each study is analyzed, and health differences among infants, children, and adults who have been vaccinated and those who have not are presented and put in context. Readers will find information on: The infant/child vaccination schedule Thimerosal in vaccines Live virus vaccines The human papillomavirus (HPV) vaccine Vaccination and Gulf War illness Influenza (flu) vaccines Hepatitis B vaccination The COVID-19 vaccine Vaccines during pregnancy Given the massive push to vaccinate the entire global population, this book is timely and necessary for individuals to make informed choices for themselves and their families.
Vaxxers: A Pioneering Moment in Scientific History
by Sarah Gilbert Catherine Green*The inside story of the Oxford AstraZeneca vaccine, from two of the leading scientists who created it. Fully updated for paperback publication with a preface and a new chapter .*This is the story of a race - not against other vaccines or other scientists, but against a deadly and devastating virus. On 1 January 2020, Sarah Gilbert, Professor of Vaccinology at Oxford University, read an article about four people in China with a strange pneumonia. Within two weeks, she and her team had designed a vaccine against a pathogen that no one had ever seen before. Less than 12 months later, vaccination was rolled out across the world to save millions of lives from Covid-19. In Vaxxers, we hear directly from Professor Gilbert and her colleague Dr Catherine Green as they reveal the inside story of making the Oxford AstraZeneca vaccine and the cutting-edge science and sheer hard work behind it. This is their story of fighting a pandemic as ordinary people in extraordinary circumstances. Sarah and Cath share the heart-stopping moments in the eye of the storm; they separate fact from fiction; they explain how they made a safe vaccine in record time with the eyes of the world watching; and they give us hope for the future. Vaxxers invites us into the lab to find out how science will save us from this pandemic, and how we can prepare for the inevitable next one.(P) 2021 Hodder & Stoughton Ltd
Vaxxers: The Inside Story of the Oxford AstraZeneca Vaccine and the Race Against the Virus
by Sarah Gilbert Catherine GreenTHE SUNDAY TIMES BESTSELLER*Radio 4 Book of the Week*This is the story of a race - not against other vaccines or other scientists, but against a deadly and devastating virus.On 1 January 2020, Sarah Gilbert, Professor of Vaccinology at Oxford University, read an article about four people in China with a strange pneumonia. Within two weeks, she and her team had designed a vaccine against a pathogen that no one had ever seen before. Less than 12 months later, vaccination was rolled out across the world to save millions of lives from Covid-19.In Vaxxers, we hear directly from Professor Gilbert and her colleague Dr Catherine Green as they reveal the inside story of making the Oxford AstraZeneca vaccine and the cutting-edge science and sheer hard work behind it. This is their story of fighting a pandemic as ordinary people in extraordinary circumstances. Sarah and Cath share the heart-stopping moments in the eye of the storm; they separate fact from fiction; they explain how they made a highly effective vaccine in record time with the eyes of the world watching; and they give us hope for the future.Vaxxers invites us into the lab to find out how science will save us from this pandemic, and how we can prepare for the inevitable next one.
Vaxxers: The Inside Story of the Oxford AstraZeneca Vaccine and the Race Against the Virus
by Sarah Gilbert Catherine GreenTHE SUNDAY TIMES BESTSELLER*Radio 4 Book of the Week*This is the story of a race - not against other vaccines or other scientists, but against a deadly and devastating virus.On 1 January 2020, Sarah Gilbert, Professor of Vaccinology at Oxford University, read an article about four people in China with a strange pneumonia. Within two weeks, she and her team had designed a vaccine against a pathogen that no one had ever seen before. Less than 12 months later, vaccination was rolled out across the world to save millions of lives from Covid-19.In Vaxxers, we hear directly from Professor Gilbert and her colleague Dr Catherine Green as they reveal the inside story of making the Oxford AstraZeneca vaccine and the cutting-edge science and sheer hard work behind it. This is their story of fighting a pandemic as ordinary people in extraordinary circumstances. Sarah and Cath share the heart-stopping moments in the eye of the storm; they separate fact from fiction; they explain how they made a highly effective vaccine in record time with the eyes of the world watching; and they give us hope for the future.Vaxxers invites us into the lab to find out how science will save us from this pandemic, and how we can prepare for the inevitable next one.
VCD Spectroscopy for Organic Chemists
by Philip J. Stephens Frank J. Devlin James R. CheesemanStimulated by the increasing importance of chiral molecules as pharmaceuticals and the need for enantiomerically pure drugs, techniques in chiral chemistry have been expanded and refined, especially in the areas of chromatography, asymmetric synthesis, and spectroscopic methods for chiral molecule structural characterization. In addition to synthet
VDI-Wärmeatlas: Fachlicher Träger VDI-Gesellschaft Verfahrenstechnik und Chemieingenieurwesen (Springer Reference Technik)
by Peter Stephan Stephan Kabelac Matthias Kind Dieter Mewes Karlheinz Schaber Thomas WetzelGeschrieben von Spezialisten aus Industrie und Wissenschaft, ermöglicht das Standardwerk die Auslegung technischer Apparate und Anlagen, z. B. in der Verfahrens- und der Energietechnik. Dafür werden Daten bereitgestellt, Berechnungsmethoden eingehend erläutert und Konstruktionen vorgestellt. Die 11. deutsche Auflage enthält zahlreiche neue Beiträge, die Kapitel wurden komplett überarbeitet und dem Stand der Technik angepasst. Seit über 50 Jahren ein unentbehrliches Arbeitsmittel für Ingenieure, die sich mit Fragen der Wärmeübertragung beschäftigen.
Vector: A Surprising Story of Space, Time, and Mathematical Transformation
by Robyn ArianrhodA celebration of the seemingly simple idea that allowed us to imagine the world in new dimensions—sparking both controversy and discovery. The stars of this book, vectors and tensors, are unlikely celebrities. If you ever took a physics course, the word “vector” might remind you of the mathematics needed to determine forces on an amusement park ride, a turbine, or a projectile. You might also remember that a vector is a quantity that has magnitude and (this is the key) direction. In fact, vectors are examples of tensors, which can represent even more data. It sounds simple enough—and yet, as award-winning science writer Robyn Arianrhod shows in this riveting story, the idea of a single symbol expressing more than one thing at once was millennia in the making. And without that idea, we wouldn’t have such a deep understanding of our world. Vector and tensor calculus offers an elegant language for expressing the way things behave in space and time, and Arianrhod shows how this enabled physicists and mathematicians to think in a brand-new way. These include James Clerk Maxwell when he ushered in the wireless electromagnetic age; Einstein when he predicted the curving of space-time and the existence of gravitational waves; Paul Dirac, when he created quantum field theory; and Emmy Noether, when she connected mathematical symmetry and the conservation of energy. For it turned out that it’s not just physical quantities and dimensions that vectors and tensors can represent, but other dimensions and other kinds of information, too. This is why physicists and mathematicians can speak of four-dimensional space-time and other higher-dimensional “spaces,” and why you’re likely relying on vectors or tensors whenever you use digital applications such as search engines, GPS, or your mobile phone. In exploring the evolution of vectors and tensors—and introducing the fascinating people who gave them to us—Arianrhod takes readers on an extraordinary, five-thousand-year journey through the human imagination. She shows the genius required to reimagine the world—and how a clever mathematical construct can dramatically change discovery’s direction.
Vector Biology, Ecology and Control
by Peter W. AtkinsonThe control of mosquitoes and other insect vectors of human pathogens in an area-wide, environmentally and sustainable way is critical to solving global health problems in the developing world but also to industrialized countries that already have in place efficient vector control programs. The rapid spread of West Nile virus through the United States provides one example of how even a highly developed country can be relatively powerless against the spread of mosquito-borne disease. This volume illustrates how the efforts over half a century of a single investigator, Mir S. Mulla, and his students and collaborators have achieved sustainable vector insect control in regions of the world extending from the south-western United States to south-east Asia. These control strategies have been refined over these decades and now are employed in a diversity of ecosystems. Increased public awareness of global health and the importance placed on this for the future well-being of the entire human population makes the deployment and refinement of these strategies even more timely.