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Computational Modeling in Tissue Engineering: A Computational Modeling Approach (Studies in Mechanobiology, Tissue Engineering and Biomaterials #10)

by Liesbet Geris

One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in: (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying and optimizing the tissue engineering process, e.g. by adapting bioreactor design to improve quality and quantity of the final product; and (iii) assessing the influence of the in vivo environment on the behavior of the tissue engineering product, e.g. by investigating vascular ingrowth. The book presents examples of each of the above mentioned areas of computational modeling. The underlying tissue engineering applications will vary from blood vessels over trachea to cartilage and bone. For the chapters describing examples of the first two areas, the main focus is on (the optimization of) mechanical signals, mass transport and fluid flow encountered by the cells in scaffolds and bioreactors as well as on the optimization of the cell population itself. In the chapters describing modeling contributions in the third area, the focus will shift towards the biology, the complex interactions between biology and the micro-environmental signals and the ways in which modeling might be able to assist in investigating and mastering this complexity. The chapters cover issues related to (multiscale/multiphysics) model building, training and validation, but also discuss recent advances in scientific computing techniques that are needed to implement these models as well as new tools that can be used to experimentally validate the computational results.

Computational Modeling of Inorganic Nanomaterials (Series in Materials Science and Engineering)

by Stefan T. Bromley Martijn A. Zwijnenburg

Computational Modeling of Inorganic Nanomaterials provides an accessible, unified introduction to a variety of methods for modeling inorganic materials as their dimensions approach the nanoscale. With contributions from a team of international experts, the book guides readers on choosing the most appropriate models and methods for studying the stru

Computational Modeling of Multilevel Organisational Learning and Its Control Using Self-modeling Network Models (Studies in Systems, Decision and Control #468)

by Gülay Canbaloğlu Jan Treur Anna Wiewiora

Although there is much literature on organisational learning, mathematical formalisation and computational simulation, there is no literature that uses mathematical modelling and simulation to represent and explore different facets of multilevel learning. This book provides an overview of recent work on mathematical formalisation and computational simulation of multilevel organisational learning by exploiting the possibilities of self-modeling network models to address it. This is the first book addressing mathematical formalisation and computational modeling of multilevel organisational learning in a systematic, principled manner. A self-modeling network modeling approach from AI and Network Science is used where in a reflective manner some of the network nodes (called self-model nodes) represent parts of the network’s own network structure characteristics. This is supported by a dedicated software environment allowing to design and implement (higher-order) adaptive network models by specifying them in a conceptual manner at a high level of abstraction in a standard table format, without any need of algorithmic specification or programming. This modeling approach allows to model the development of knowledge in an organisational setting in a neatly structured manner at three different levels for the usage, adaptation and control, respectively, of the underlying mental models. Several examples of realistic cases of multilevel organisational learning are used to illustrate the approach. Crucial concepts such as the aggregation of mental models to form shared mental models out of individual mental models are addressed extensively. It is shown how to model context-sensitive control of organisational learning taking into account a wide variety of context factors, for example relating to levels of expertise of individuals or to leadership styles of managers involved. Mathematical equilibrium analysis of models of organisational learning is also addressed, among others allowing verification of correctness of the implemental models in comparison to their conceptual design. Chapters in this book also contribute to the Management and Business Sciences research by demonstrating how computational modeling can be used to capture complex management phenomena such as multilevel organizational learning. This book has a potential implication for practice by demonstrating how computational modeling can be used to capture learning scenarios, which then provide a basis for more informed managerial decisions.

Computational Modeling of Multiphase Geomaterials

by Fusao Oka Sayuri Kimoto

Computational Modeling of Multiphase Geomaterials discusses how numerical methods play a very important role in geotechnical engineering and in the related activity of computational geotechnics. It shows how numerical methods and constitutive modeling can help predict the behavior of geomaterials such as soil and rock.After presenting the fundament

Computational Modeling of Polymer Composites: A Study of Creep and Environmental Effects (Applied and Computational Mechanics)

by Samit Roy J.N. Reddy

This book provides a better understanding of the theories associated with finite element models of elastic and viscoelastic response of polymers and polymer composites. It covers computational modeling and life-prediction of polymers and polymeric composites in aggressive environments. It begins with a review of mathematical preliminaries, equations of anisotropic elasticity, and then presents finite element analysis of viscoelasticity and the diffusion process in polymers and polymeric composites. The book provides a reference for engineers and scientists and can be used as a textbook in graduate courses.

Computational Modeling of Pulverized Coal Fired Boilers

by Vivek V. Ranade Devkumar F. Gupta

Harness State-of-the-Art Computational Modeling Tools Computational Modeling of Pulverized Coal Fired Boilers successfully establishes the use of computational modeling as an effective means to simulate and enhance boiler performance. This text factors in how computational flow models can provide a framework for developing a greater understanding o

Computational Modeling of Shallow Geothermal Systems (Multiphysics Modeling)

by Rafid Al-Khoury

A Step-by-step Guide to Developing Innovative Computational Tools for Shallow Geothermal SystemsGeothermal heat is a viable source of energy and its environmental impact in terms of CO2 emissions is significantly lower than conventional fossil fuels. Shallow geothermal systems are increasingly utilized for heating and cooling of buildings and green

Computational Modeling of Tensegrity Structures: Art, Nature, Mechanical and Biological Systems

by Buntara Sthenly Gan

This book provides an in-depth, numerical investigation of tensegrity systems from a structural point of view, using the laws of fundamental mechanics for general pin-jointed systems with self-stressed mechanisms. Tensegrity structures have been known for decades, mostly as an art of form for monuments in architectural design. In Computational Modeling of Tensegrity Structures, Professor Buntara examines these formations, integrating perspectives from mechanics, robotics, and biology, emphasizing investigation of tensegrity structures for both inherent behaviors and their apparent ubiquity in nature. The author offers numerous examples and illustrative applications presented in detail and with relevant MATLAB codes. Combining a chapter on the analyses of tensegrity structures along with sections on computational modeling, design, and the latest applications of tensegrity structures, the book is ideal for R&D engineers and students working in a broad range of disciplines interested in structural design.

Computational Modeling of Underground Coal Gasification

by Vivek V. Ranade Sanjay M Mahajani Ganesh Arunkumar Samdani

The book deals with development of comprehensive computational models for simulating underground coal gasification (UCG). It starts with an introduction to the UCG process and process modelling inputs in the form of reaction kinetics, flow patterns, spalling rate, and transport coefficient that are elaborated with methods to generate the same are described with illustrations. All the known process models are reviewed, and relative merits and limitations of the modeling approaches are highlighted and compared. The book describes all the necessary steps required to determine the techno-economic feasibility of UCG process for a given coal reserve, through modeling and simulation.

Computational Modeling, Optimization and Manufacturing Simulation of Advanced Engineering Materials (Advanced Structured Materials #49)

by Pablo Andrés Andrés Muñoz-Rojas

This volume presents recent research work focused in the development of adequate theoretical and numerical formulations to describe the behavior of advanced engineering materials. Particular emphasis is devoted to applications in the fields of biological tissues, phase changing and porous materials, polymers and to micro/nano scale modeling. Sensitivity analysis, gradient and non-gradient based optimization procedures are involved in many of the chapters, aiming at the solution of constitutive inverse problems and parameter identification. All these relevant topics are exposed by experienced international and inter institutional research teams resulting in a high level compilation. The book is a valuable research reference for scientists, senior undergraduate and graduate students, as well as for engineers acting in the area of computational material modeling.

Computational Modelling and Advanced Simulations (Computational Methods in Applied Sciences #24)

by Justín Murín Vladimír Kompiš Vladimír Kutiš

This book contains selected, extended papers presented at the thematic ECCOMAS conference on Computational Modelling and Advanced Simulations (CMAS2009) held in Bratislava, Slovakia, June 30 - July 3, 2009. Modelling and simulation of engineering problems play a very important role in the classic and new composite material sciences, and in design and computational prototyping of modern and advanced technologic parts and systems. According to this, the existing numerical methods have been improved and new numerical methods have been established for modelling and simulation of more and more complex and complicated engineering problems. The present book should contribute to the effort to make modelling and simulation more effective and accurate.

Computational Modelling and Simulation of Aircraft and the Environment, Volume 2: Aircraft Dynamics (Aerospace Series)

by Dominic J. Diston

Computational Modelling and Simulation of Aircraft and the Environment An in-depth discussion of aircraft dynamics modelling and simulation This book provides a comprehensive guide to modelling and simulation from basic physical and mathematical principles, giving the reader sufficient information to be able to build computational models of aircraft for the purposes of simulation and evaluation. Highly relevant to practitioners, it takes into account the multi-disciplinary nature of aerospace products and the integrated nature of the models needed in order to represent them. Volume 1- Platform Kinematics and Synthetic Environment focused on the modelling of a synthetic environment in which aircraft operate and its spatial relationship with vehicles that are situated and moving within it. This volume focuses on the modelling of aircraft and the interpretation of their flight dynamics. Key features: Includes chapters on equations of motion, fixed-wing aerodynamics, longitudinal flight and gas turbines, as well as an opening chapter that presents an overview of flight modelling and a concluding chapter that presents a number of additional topics such as aircraft structures and embedded systems. Serves as both a student text and practitioner reference. Follows on from previous Aerospace Series titles, offering a complementary view of vehicles and systems from the perspectives of mathematics, physics and simulation. This book offers a comprehensive guide for senior, graduate and postgraduate students of aerospace engineering as well as professional engineers involved in the modelling and simulation of aircraft.

Computational Modelling in Hydraulic and Coastal Engineering

by Christopher Koutitas Panagiotis D. Scarlatos

Computational simulation methods have a range of applications in hydraulic and coastal engineering. This textbook provides an introductory but comprehensive coverage of these methods. It emphasizes the finite differences method with applications in reservoir management, closed-conduit hydraulics, free-surface channel flows, surface gravity waves, groundwater movement and mass transport processes. It focuses on applications rather than lengthy theories or derivations of complex formulas and is supported by a wealth of hands-on numerical examples, PowerPoint presentations, learning assignment projects and quizzes.

Computational Modelling in Industry 4.0: A Sustainable Resource Management Perspective

by Ali Akbar Shaikh Irfan Ali Neha Gupta Prasenjit Chatterjee Ali AlArjani

This book addresses the different problems, practices, challenges and opportunities in sustainable resource management with the help of decision-making techniques to showcase the relevance of computational modelling approaches in sustainable management and Industry 4.0. It aims to address the inherent complexity of managing ecosystems, particularly with respect to involvement of multi-stakeholders, lack of information and uncertainties. Critical analyses are made to point out the need for, and propose a call to, a new way of thinking about sustainable resource management. This book will be useful for academicians, researchers, and industrialists in the field of industrial and production engineering.

Computational Modelling of Bifurcations and Instabilities in Fluid Dynamics (Computational Methods in Applied Sciences #50)

by Alexander Gelfgat

Instabilities of fluid flows and the associated transitions between different possible flow states provide a fascinating set of problems that have attracted researchers for over a hundred years. This book addresses state-of-the-art developments in numerical techniques for computational modelling of fluid instabilities and related bifurcation structures, as well as providing comprehensive reviews of recently solved challenging problems in the field.

Computational Modelling of Concrete and Concrete Structures

by Günther Meschke

Computational Modelling of Concrete and Concrete Structures contains the contributions to the EURO-C 2022 conference (Vienna, Austria, 23-26 May 2022). The papers review and discuss research advancements and assess the applicability and robustness of methods and models for the analysis and design of concrete, fibre-reinforced and prestressed concrete structures, as well as masonry structures. Recent developments include methods of machine learning, novel discretisation methods, probabilistic models, and consideration of a growing number of micro-structural aspects in multi-scale and multi-physics settings. In addition, trends towards the material scale with new fibres and 3D printable concretes, and life-cycle oriented models for ageing and durability of existing and new concrete infrastructure are clearly visible. Overall computational robustness of numerical predictions and mathematical rigour have further increased, accompanied by careful model validation based on respective experimental programmes. The book will serve as an important reference for both academics and professionals, stimulating new research directions in the field of computational modelling of concrete and its application to the analysis of concrete structures. EURO-C 2022 is the eighth edition of the EURO-C conference series after Innsbruck 1994, Bad Gastein 1998, St. Johann im Pongau 2003, Mayrhofen 2006, Schladming 2010, St. Anton am Arlberg 2014, and Bad Hofgastein 2018. The overarching focus of the conferences is on computational methods and numerical models for the analysis of concrete and concrete structures.

Computational Modelling of Concrete Structures: Proceedings Of The Euro-c 2006 Conference, Mayrhofen, Austria, 27-30 March 2006

by Nenad Bićanić René De Borst Herbert Mang Günther Meschke

Since 1984 the EURO-C conference series (Split 1984, Zell am See 1990, Innsbruck 1994, Badgastein 1998, St Johann im Pongau 2003, Mayrhofen 2006, Schladming 2010) has provided a forum for academic discussion of the latest theoretical, algorithmic and modelling developments associated with computational simulations of concrete and concrete structure

Computational Modelling of Concrete Structures

by Nenad Bićanić Herbert Mang Günther Meschke René De Borst

The EURO-C conference series (Split 1984, Zell am See 1990, Innsbruck 1994, Badgastein 1998, St Johann im Pongau 2003, Mayrhofen 2006, Schladming 2010, St Anton am Alberg 2014) brings together researchers and practising engineers concerned with theoretical, algorithmic and validation aspects associated with computational simulations of concrete and

Computational Modelling of Concrete Structures: Proceedings of the EURO-C 2006 Conference, Mayrhofen, Austria, 27-30 March 2006

by Günther Meschke; René de Borst; Herbert Mang; Nenad Bićanić

This conference proceedings brings together the work of researchers and practising engineers concerned with computational modelling of complex concrete, reinforced concrete and prestressed concrete structures in engineering practice. The subjects considered include computational mechanics of concrete and other cementitious materials, including masonry. Advanced discretisation methods and microstructural aspects within multi-field and multi-scale settings are discussed, as well as modelling formulations and constitutive modelling frameworks and novel experimental programmes. The conference also considered the need for reliable, high-quality analysis and design of concrete structures in regard to safety-critical structures, with a view to adopting these in codes of practice or recommendations. The book is of special interest to researchers in computational mechanics, and industry experts in complex nonlinear simulations of concrete structures.

Computational Modelling of Concrete Structures: Proceedings of the Conference on Computational Modelling of Concrete and Concrete Structures (EURO-C 2018), February 26 - March 1, 2018, Bad Hofgastein, Austria

by Bernhard Pichler Günther Meschke Jan G. Rots

The EURO-C conference series (Split 1984, Zell am See 1990, Innsbruck 1994, Badgastein 1998, St. Johann im Pongau 2003, Mayrhofen 2006, Schladming 2010, St. Anton am Arlberg 2014, and Bad Hofgastein 2018) brings together researchers and practising engineers concerned with theoretical, algorithmic and validation aspects associated with computational simulations of concrete and concrete structures. Computational Modelling of Concrete Structures reviews and discusses research advancements and the applicability and robustness of methods and models for reliable analysis of complex concrete, reinforced concrete and pre-stressed concrete structures in engineering practice. The contributions cover both computational mechanics and computational modelling aspects of the analysis and design of concrete and concrete structures: Multi-scale cement and concrete research: experiments and modelling Aging concrete: from very early ages to decades-long durability Advances in material modelling of plain concrete Analysis of reinforced concrete structures Steel-concrete interaction, fibre-reinforced concrete, and masonry Dynamic behaviour: from seismic retrofit to impact simulation Computational Modelling of Concrete Structures is of special interest to academics and researchers in computational concrete mechanics, as well as industry experts in complex nonlinear simulations of concrete structures.

Computational Modelling of Objects Represented in Images. Fundamentals, Methods and Applications: Proceedings of the International Symposium CompIMAGE 2006 (Coimbra, Portugal, 20-21 October 2006) (Lecture Notes In Computer Science / Image Processing, Computer Vision, Pattern Recognition, And Graphics Ser.)

by João Manuel R.S. Tavares R.M. Natal Jorge

This book contains keynote lectures and full papers presented at the International Symposium on Computational Modelling of Objects Represented in Images (CompIMAGE), held in Coimbra, Portugal, on 20-21 October 2006. International contributions from nineteen countries provide a comprehensive coverage of the current state-of-the-art in the fields of: - Image Processing and Analysis; - Image Segmentation; - Data Interpolation; - Registration, Acquisition and Compression; - 3D Reconstruction; - Objects Tracking; - Motion and Deformation Analysis; - Objects Simulation; - Medical Imaging; - Computational Bioimaging and Visualization. Related techniques also covered in this book include the finite element method, modal analyses, stochastic methods, principal and independent components analyses and distribution models. Computational Modelling of Objects Represented in Images will be useful to academics, researchers and professionals in Computational Vision (image processing and analysis), Computer Sciences, and Computational Mechanics.

Computational Modelling of Objects Represented in Images III: Fundamentals, Methods and Applications

by Paolo Di Giamberardino & Daniela Iacoviello R.M. Natal Jorge & João Manuel R.S. Tavares

Computational Modelling of Objects Represented in Images: Fundamentals, Methods and Applications III contains all contributions presented at the International Symposium CompIMAGE 2012 - Computational Modelling of Object Presented in Images: Fundamentals, Methods and Applications (Rome, Italy, 5-7 September 2012). The contributions cover the state-o

Computational Models for CO2 Geo-sequestration & Compressed Air Energy Storage (Sustainable Energy Developments)

by Rafid Al-Khoury Jochen Bundschuh

A comprehensive mathematical and computational modeling of CO2 Geosequestration and Compressed Air Energy StorageEnergy and environment are two interrelated issues of great concern to modern civilization. As the world population will soon reach eight billion, the demand for energy will dramatically increase, intensifying the use of fossil fuels. Ut

Computational Models for Polydisperse Particulate and Multiphase Systems

by Daniele L. Marchisio Rodney O. Fox

Providing a clear description of the theory of polydisperse multiphase flows, with emphasis on the mesoscale modelling approach and its relationship with microscale and macroscale models, this all-inclusive introduction is ideal whether you are working in industry or academia. Theory is linked to practice through discussions of key real-world cases (particle/droplet/bubble coalescence, break-up, nucleation, advection and diffusion and physical- and phase-space), providing valuable experience in simulating systems that can be applied to your own applications. Practical cases of QMOM, DQMOM, CQMOM, EQMOM and ECQMOM are also discussed and compared, as are realizable finite-volume methods. This provides the tools you need to use quadrature-based moment methods, choose from the many available options, and design high-order numerical methods that guarantee realizable moment sets. In addition to the numerous practical examples, MATLAB scripts for several algorithms are also provided, so you can apply the methods described to practical problems straight away.

Computational Morphologies: Design Rules Between Organic Models and Responsive Architecture

by Michela Rossi Giorgio Buratti

This book represents an invaluable and up-to-date international exchange of research, case studies and best practice to tackle the challenges of digital technology, computer-aided design, 3D modeling, prototyping machines and computational design. With contributions from leading experts in the field of industrial design and cultural heritage, it is split into three parts. The first part explores basic rules of design, design models and shape grammar, including the management of complex forms, and proves that innovative concepts may be derived from organic models using generative design. The second part then investigates responsive design, describing how to manage the changing morphologies of buildings through pre-programmed mechanisms of real-time response and feedback embedded in inhabitable spaces. Lastly, the third part focuses on digital heritage and its capability to increase the interaction and manipulation of object and concepts, ranging from augmented reality to modeling generative tools. The book gathers peer-reviewed papers presented at the eCAADe (Education and Research in Computer-Aided Architectural Design in Europe) Regional International Symposium, held in Milan, Italy, in 2015.

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