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Fluorescence Lifetime Imaging Ophthalmoscopy
by Martin Zinkernagel Chantal DysliThis book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.
Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics
by Laura Marcu Paul M. W. French Daniel S. ElsonDuring the past two decades, there has been an increasing appreciation of the significant value that lifetime-based techniques can add to biomedical studies and applications of fluorescence. Bringing together perspectives of different research communities, Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Dia
Fluorescence Molecular Tomography: Principles and Applications
by Huabei JiangFluorescence Molecular Tomography: Principles and Applications is the first book to cover the underlying principles and practical applications of fluorescence molecular tomography (FMT) in a systematic manner. Using a tutorial approach, the text begins with an overview of the fundamentals of FMT and goes on to detail image reconstruction approaches (including linear and nonlinear reconstruction algorithms), FMT instrumentations (including time-domain, frequency-domain, and continuous-wave domain systems), and implementation of image-enhancing schemes (including both software and hardware approaches). Further chapters examine multimodal approaches combining photoacoustic tomography (PAT), computed tomography (CT), single-photon emission tomography (SPECT), and magnetic resonance imaging (MRI) and discuss bioluminescence tomography and miniaturized FMT from hand-held to endoscopic FMT. A final chapter looks at clinical applications and animal studies. This authoritative and practical guide will serve as a valuable reference for researchers, scientists, clinicians, and industry professionals.The first book dedicated to fluorescence molecular tomography (FMT); Covers underlying principles and practical applications; Written by a leading FMT research pioneer and expert.
Fluorescence of Living Plant Cells for Phytomedicine Preparations
by Victoria Vladimirovna RoshchinaFluorescence of Living Plant Cells for Phytomedicine Preparations reveals how valuable medicinal compounds can be identified through the application of vital fluorescence in plant cells. The book explains the roles that fluorescent compounds play in plant physiology and promotes our knowledge of plant secretory cells and phytopreparations. Supported by vivid illustrations, the book reveals how actinic light – light that induces fluorescence in leaves and flowers – can be used in the identification of secretory cells within plant tissue that may be the repository of valuable medicinal compounds. The book demonstrates the potential of fluorescence in pharmacological analysis with detailed methods for applying fluorescence to identify these deposits of natural drugs. As such, this groundbreaking book contains methods of express-pharmaceutical analysis that could open new horizons in pharmacy and the cultivation of medicinal plants. Features Describes various fluorescence microscopy techniques for the localization of compounds contained in plants with pharmaceutical interest Provides an analysis of pharmaceutical material based on autofluorescence and histochemical reactions for numerous medicinal plant species Demonstrates practices for providing optimal growing conditions and improving the quality of the compounds Showing the readiness of plant raw material for pharmaceutical industry, this book will appeal to professionals in the pharmaceutical industry and students and researchers in the fields of phytochemistry, botany and pharmaceutical sciences.
Fluorescence Spectroscopy and Microscopy in Biology (Springer Series on Fluorescence #20)
by Radek Šachl Mariana AmaroThis book provides the reader with an updated comprehensive view of the rapidly developing and fascinating field of fluorescence spectroscopy and microscopy. In recent years, fluorescence spectroscopy and microscopy have experienced rapid technological development, which has enabled the detection and monitoring of single molecules with high spatial and temporal resolution. Thanks to these developments, fluorescence has become an even more popular method in physical, biological and related fields. This book guides the reader through both basic and advanced fluorescence spectroscopy and microscopy approaches with a focus on their applications in membrane and protein biophysics. Each of the four parts: A - Fluorescence Spectroscopy, B - Fluorescence Microscopy, C - Applications of Fluorescence Spectroscopy and Microscopy to biological membranes and D - Applications of Fluorescence Spectroscopy to protein studies are written by experts within the field. The book is intended for both complete beginners who want to quickly orient themselves in the large number of existing fluorescent methods, as well as for advanced readers who are interested in particular methods and their proper use.
Fluorescence Studies of Polymer Containing Systems
by Karel ProcházkaThis volume describes the application of fluorescencespectroscopy in polymer research. The first chapters outline the basicprinciples of the conformational and dynamic behavior of polymers and reviewthe problems of polymer self-assembly. Subsequent chapters introduce the theoreticalprinciples of advanced fluorescence methods and typical examples of theirapplication in polymer science. The book closes with several reviews of variousfluorescence applications for studying specific aspects of polymer-solution behavior. It is a useful resource for polymerscientists and experts in fluorescence spectroscopy alike, facilitating theircommunication and cooperation.
Fluorescent Imaging in Medicinal Chemistry (Topics in Medicinal Chemistry #34)
by Zhen ChengThis book reviews the most recent developments of fluorescent imaging techniques for medicinal chemistry research and biomedical applications, including cell imaging, in vitro diagnosis and in vivo imaging. Fluorescent imaging techniques play an important role in basic research, drug discovery and clinical translation. They have great impact to many fields including chemical biology, cell biology, medical imaging, cancer diagnosis and treatment, pharmaceutical science, among others, and they have facilitated our understanding of diseases and helped to develop many novel powerful tools for imaging and treatment of diseases. This book will appeal to scientists from numerous fields such as chemistry, pharmaceutical science, biology, materials science, and medicine, and it will serve as a very useful and handy resource for readers with different levels of scientific knowledge, ranging from entry level to professional level.
Fluorescent Materials for Cell Imaging
by Fu-Gen WuThis book focuses on the latest fluorescent materials for cell imaging. Cell imaging is a widely used basic technique that helps scientists gain a better understanding of biological functions through studies of cellular structure and dynamics. In the past decades, the development of a variety of new fluorescent materials has significantly extended the applications of cellular imaging techniques. This book presents recently developed fluorescent materials, including semiconductor quantum dots, carbon dots, silicon nanoparticles, metal nanoclusters, upconversion nanoparticles, conjugated polymers/polymer dots, aggregation-induced emission (AIE) probes, and coordination compounds, used for various cellular imaging purposes. It will appeal to cell biologists and other researchers in academia, industry and clinical settings who are interested in the technical development and advanced applications of fluorescence imaging in cells, tissues and organisms to explore the mechanisms of biological functions and diseases.
Fluorescent Microscopy (Methods in Molecular Biology #2440)
by Bryan HeitThis volume provides both experienced and new microscopists with methods and protocols to perform fluorescence microscopy-based experiments. The book is divided into four parts detailing basic fluorescent microscopy, quantitative methods, imaging living animals, human tissue samples, approaches for imaging at a near-molecular level, and approaches to image analysis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Fluorescent Microscopy aims to be a useful practical guide to researches to help further their study in this field.
Fluorescent Organic Nanoparticles: New Generation Materials with Diverse Analytical and Biomedical Applications (SpringerBriefs in Materials)
by Waseem A. Wani Mohammad Shahid Afzal Hussain Mohamed Fahad AlAjmiThis book provides a critical review of recent advances in the development of fluorescent organic nanoparticles as materials of choice for the design and fabrication of sensors, bioimaging agents and drug delivery systems. The properties and functions of nanoparticles differ significantly from those of their parent entities or their bulk phases. Two of their most important features are their increased surface-to volume ratio, and the formation of surface structures differing from those in their bulk phases. In addition, the book discusses the synthesis of fluorescent conjugated polymers, self-assembled fluorescent nanoparticles, polydopamine nanoparticles, and aggregation-induced-emission or aggregation-induced-emission enhancement nanomaterials. In closing, the book provides an outlook on future research and development in fluorescent organic nanoparticles as smart materials with an impressive range of potential applications.
Fluorescent Protein-Based Biosensors
by Jin Zhang Qiang Ni Robert H NewmanThis book features step-by-step, readily reproducible protocols used to describe several methods in which fluorescent protein-based reporters can be used to gain unique insights into the regulation of cellular signal transduction.
The Fluorescent Protein Revolution
by Vijay K. Vaishnavi William KuechlerAdvances in fluorescent proteins, live-cell imaging, and superresolution instrumentation have ushered in a new era of investigations in cell biology, medicine, and physiology. From the identification of the green fluorescent protein in the jellyfish Aequorea victoria to the engineering of novel fluorescent proteins, The Fluorescent Protein Revoluti
Fluorescent Tools for Imaging Oxidative Stress in Biology (Springer Theses)
by Amandeep KaurThis thesis advances the long-standing challenge of measuring oxidative stress and deciphering its underlying mechanisms, and also outlines the advantages and limitations of existing design strategies. It presents a range of approaches for the chemical synthesis of fluorescent probes that detect reversible changes in cellular oxidative stress. The ability to visualise cellular processes in real-time is crucial to understanding disease development and streamline treatment, and this can be achieved using fluorescent tools that can sense reversible disturbances in cellular environments during pathogenesis. The perturbations in cellular redox state are of particular current interest in medical research, since oxidative stress is implicated in the pathogenesis of a number of diseases.The book investigates different strategies used to achieve ratiometric fluorescence output of the reversible redox probes, which nullify concentration effects associated with intensity-based probes. It also describes suitable approaches to target these probes to specific cellular organelles, thereby enabling medical researchers to visualise sub-cellular oxidative stress levels, and addressing the typically poor uptake of chemical tools into biological studies. In total it reports on four new probes that are now being used by over twenty research groups around the globe, and two of which have been commercialised. The final chapters of this thesis demonstrate successful applications of the sensors in a variety of biological systems ranging from prokaryotes to mammalian cells and whole organisms. The results described clearly indicate the immense value of collaborative, cross-disciplinary research.
Fluoride and Fluorocarbon Toxicity: Sources, Issues, and Remediation (Environmental Science and Engineering)
by Nitish KumarThis book presents fluoride and fluorocarbon toxicity with respect to remediation and health issues. It covers sources of fluoride and fluorocarbon contamination, its impact on human health, and prospective remediation by multi-disciplinary approaches with the application of recent advanced technology. This book brings together a diverse group of researchers from different disciplines to address the challenges posed by global mass poisoning caused by fluoride and fluorocarbon contamination. The book sheds light on the global environmental issues and proposes solutions to contamination through multi-disciplinary approaches. The book contains three parts. The first part describes the different sources and distribution of fluoride and fluorocarbon in soil and water. The second part explains the health risks linked to fluoride and fluorocarbon toxicity. The third part addresses sustainable fluoride and fluorocarbon toxicity mitigation strategies and the potential applications of recent biotechnology in providing solutions. This book is a valuable resource to students, academics, researchers, and environmental professionals working in the field of fluoride and fluorocarbon contamination.
Fluoride Removal from Groundwater by Adsorption Technology
by Abdulai SalifuIn the Eastern corridor of Northern region of Ghana, presence of high fluoride concentration in the groundwater has made many drilled boreholes unusable for drinking. Little is, however, known about the factors contributing to the occurrence of high fluoride in this part of Ghana and it’s spatial distribution. Treatment of the fluoride-contaminated groundwater by adsorption is also hampered by the lack of suitable adsorbents that are locally available. Based on principal component analysis, and saturation indices calculations, this thesis highlights that, the predominant mechanisms controlling the fluoride enrichment probably include calcite precipitation and Na/Ca exchange processes, both of which deplete Ca from the groundwater, and promote the dissolution of fluorite. The mechanisms also include F-/OH- anion exchange processes, as well as evapotranspiration processes which concentrate the fluoride ions, hence increasing its concentration in the groundwater. Spatial mapping showed that the high fluoride groundwaters occur predominantly in the Saboba, Cheriponi and Yendi districts. The thesis further highlights that, modifying the surface of indigenous materials by an aluminium coating process, is a very promising approach to develop a suitable fluoride adsorbent. Aluminum oxide coated media reduced fluoride in water from 5. 0 ± 0.2 mg/L to ≤ 1.5 mg/L (which is the WHO health based guideline for fluoride), in both batch and continuous flow column experiments in the laboratory. Kinetic and isotherm studies, thermodynamic calculations, as well as analytical results from Fourier Transform Infrared Spectroscopy and Raman spectroscopy, suggest the mechanism of fluoride adsorption onto aluminium oxide coated media involved both physisorption and chemisorption processes. Field testing in a fluoritic community in Northern Ghana showed that the adsorbent is also capable of treating fluoride-contaminated groundwater in field conditions, suggesting it is a promising defluoridation adsorbent. The adsorbent also showed good regenerability potential that would allow re-use, which could make it practically and economically viable. Additional research is, however, required to further increase the fluoride adsorption capacity of developed adsorbent.
Fluorides in Drinking Water: Source, Issue, and Mitigation Strategies (Environmental Science and Engineering)
by Kartika SharmaThis book brings together a diverse group of researchers to address the challenges posed by global mass poisoning caused by fluoride contamination of water bodies. The book sheds light on this global environmental issue and proposes solutions to contamination through multi-disciplinary approaches. Water is considered a vital resource because it is necessary for all aspects of human and ecosystem survival. However, due to natural processes and anthropogenic activities, various pollutants have been added to the water system. Among these, fluoride and fluorocarbons (fluorinated carbon) are some of the most serious pollutants. It occurs naturally in several minerals and in trace quantities in water. Due to its characteristics, it is very widely used in medicine, dentistry, industry, or agriculture. Fluoride content in drinking water is very important from health point of view as because it has long been recognized as a constituents of bones, teeth, soft tissues, and body fluids. On the other hand, its universality possesses a real threat to the human body in the form of acute and chronic poisoning. There are reports that excessive fluoride intake for extended period causes adverse effects of health such as fluorosis, cancer, arthritis, and other diseases. It has also been observed that fluoride in excess affects human intelligence, especially in children, who are most susceptible to early fluoride toxicity. This book contains three sections. The first section describes the different sources and distribution of fluoride in water ecosystem. The second section explains the health risks linked to fluoride poisoning. The third section addresses sustainable fluoride toxicity mitigation strategies and the potential applications of recent biological technology in providing solutions. This book is a valuable resource to students, academics, researchers, and environmental professionals doing fieldwork on fluoride and fluorocarbons contamination throughout the world.
Flush! (Fountas & Pinnell Classroom, Guided Reading)
by Susan BuckleyNIMAC-sourced textbook. Have You Ever Wondered where your poop goes? Find out what happens after you flush—and why it matters.
Flush!
by Buffy SilvermanExplore the world of plumbing when Andy and Lizzie learn how the pipes in their house work. Some pipes carry out dirty water while others carry in clean water.
Flushed with Pride: The Story of Thomas Crapper
by Wallace RayburnFlushed with Pride celebrates the life and times of Thomas Crapper, the man who revolutionised the nation's water closets and plumber By Appointment to Edward VII. First published 20 years ago, this fascinating book achieved cult status on both sides of the Atlantic and is now reissued for the delectation of loo readers everywhere.
Fluvial, Environmental and Coastal Developments in Hydraulic Engineering: Proceedings of the International Workshop on State-of-the-Art Hydraulic Engineering, Bari, Italy, 16-19 February 2004
by Michele Mossa Youichi Yasuda Hubert ChansonComprising the Proceedings of the International Workshop on State-of-the-Art Hydraulic Engineering held in Bari, Italy on 16-19 February 2004, this volume presents an in-depth investigation of the energy loss of skimming flows under a range of discharges, step and dam heights, and channel slopes. Including a wealth of information, the volume is div
Fluvial Hydrodynamics: Hydrodynamic and Sediment Transport Phenomena (GeoPlanet: Earth and Planetary Sciences)
by Subhasish DeyThis revised second edition of the book presents an improvement of the original version in terms of recent research, corrections, and outline. The state of the art in fluvial hydrodynamics can be examined only through a careful exploration of the theoretical development and applied engineering technology. This second, updated edition focuses, since most up-to-date research findings in the field are presented, on the research aspects that involve a comprehensive knowledge of sediment dynamics in turbulent flows. It begins with the fundamentals of hydrodynamics and particle motion followed by turbulence characteristics related to sediment motion. Sediment dynamics are described from a classical perspective by applying the mean bed shear approach and additionally incorporating a statistical description for the role of turbulence. It is intended to design as a course textbook in graduate / research level and a guide for the field engineers as well, keeping up with modern technological developments. One of the most important additions is that at the end of each chapter, varieties of problems were given. Therefore, as a simple prerequisite, the background of the readers should have a basic knowledge in hydraulics in undergraduate level and an understanding of fundamentals of calculus.
Fluvial Hydrodynamics - Solutions Manual (GeoPlanet: Earth and Planetary Sciences)
by Subhasish Dey Sk Zeeshan AliThe book provides the solutions to the unsolved problems given in the book titled Fluvial Hydrodynamics: Hydrodynamic and Sediment Transport Phenomena. The manual includes the solutions to the problems on Chapters 1 to 11, including the properties of fluid and sediment, hydrodynamic principles, turbulence in open-channel flows, sediment threshold, bedload transport, suspended-load transport, total-load transport, bedforms, river processes, scour, and dimensional analysis and similitude. It, therefore, serves as a guide for graduate students, researchers, and field engineers to solve the problems in fluvial hydrodynamics. As a prerequisite, the background of the readers should have a knowledge in fluvial hydrodynamics described in the said book and an understanding of fundamentals of calculus.
Fluvial Processes: 2nd Edition (IAHR Monographs)
by Ana Maria da Silva M. Selim YalinA stream flowing in alluvium deforms its bed surface, forming ripples, dunes, bars, etc., and, in many instances, it deforms its channel entirely, thereby creating meandering or braiding patterns. It could be said that, in general, an alluvial stream and its deformable boundary undergo a variety of fluvial processes leading to the emergence of a multitude of alluvial forms. This book concerns the physics and analytical treatment of various fluvial processes and the associated alluvial bed and plan forms listed above. Following an introductory chapter on the basics of turbulent flow and sediment transport, the book covers the origin, geometric characteristics and effects of bed forms, from small- to meso-scale (ripples, dunes, alternate and multiple bars); the initiation, geometry and mechanics of meandering streams; the computation of flow, bed deformation and the planimetric evolution of meandering streams; and braiding and delta formation. The book also covers the regime concept, the time-development of a stream towards its regime state, and the formulation of stable, or equilibrium, morphology. The book distinguishes itself by its comprehensive analysis and discussion of key processes involved in large-scale river morphodynamics. The book was written primarily for researchers and graduate students of hydraulic engineering, water resources and related branches of earth sciences, but it will also prove useful for river engineers and managers.
Fluvial Remote Sensing for Science and Management
by Patrice Carbonneau Hervé PiégayThis book offers a comprehensive overview of progress in the general area of fluvial remote sensing with a specific focus on its potential contribution to river management. The book highlights a range of challenging issues by considering a range of spatial and temporal scales with perspectives from a variety of disciplines. The book starts with an overview of the technical progress leading to new management applications for a range of field contexts and spatial scales. Topics include colour imagery, multi-spectral and hyper-spectral imagery, video, photogrammetry and LiDAR. The book then discusses management applications such as targeted, network scale, planning, land-use change modelling at catchment scales, characterisation of channel reaches (riparian vegetation, geomorphic features) in both spatial and temporal dimensions, fish habitat assessment, flow measurement, monitoring river restoration and maintenance and, the appraisal of human perceptions of riverscapes.Key Features:* A specific focus on management applications in a period of increasing demands on managers to characterize river features and their evolution at different spatial scales * An integration across all scales of imagery with a clear discussion of both ground based and airborne images* Includes a wide-range of environmental problems * Coverage of cutting-edge technology * Contributions from leading researchers in the field
Flux Bounded Tungsten Inert Gas Welding Process: An Introduction
by P Chakravarthy M Agilan N NeethuThis focus book is intended to introduce the Flux Bounded Tungsten Inert Gas Welding (FBTIG) process, which is a variant of Activated Tungsten inert gas welding process. The benefits of activating flux in the weld pool in enhancing the depth of penetration and underlying mechanisms for the same is explained in detail. The benefits of FBTIG process over other fusion welding process are highlighted. The scope for the FBTIG process to be adapted at the industrial level and the advancements in this field is detailed that enables the practicing engineers to exploit the same. Covers activated TIG process, role of activating fluxes in enhancing the depth of penetration Illustrates mechanisms associated with FBTIG process including arc constriction effect, insulation effect and reverse marangoni flow Discusses scope of FBTIG process for commercialization at the industry level Gives general overview of chronological advancements in the field of welding This book is aimed at graduate students, researchers and professionals in welding, manufacturing and engineering.