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Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms
by Mohamed Ibrahim Krishnendu ChakrabartyA microfluidic biochip is an engineered fluidic device that controls the flow of analytes, thereby enabling a variety of useful applications. According to recent studies, the fields that are best set to benefit from the microfluidics technology, also known as lab-on-chip technology, include forensic identification, clinical chemistry, point-of-care (PoC) diagnostics, and drug discovery. The growth in such fields has significantly amplified the impact of microfluidics technology, whose market value is forecast to grow from $4 billion in 2017 to $13.2 billion by 2023. The rapid evolution of lab-on-chip technologies opens up opportunities for new biological or chemical science areas that can be directly facilitated by sensor-based microfluidics control. For example, the digital microfluidics-based ePlex system from GenMarkDx enables automated disease diagnosis and can bring syndromic testing near patients everywhere. However, as the applications of molecular biology grow, the adoption of microfluidics in many applications has not grown at the same pace, despite the concerted effort of microfluidic systems engineers. Recent studies suggest that state-of-the-art design techniques for microfluidics have two major drawbacks that need to be addressed appropriately: (1) current lab-on-chip systems were only optimized as auxiliary components and are only suitable for sample-limited analyses; therefore, their capabilities may not cope with the requirements of contemporary molecular biology applications; (2) the integrity of these automated lab-on-chip systems and their biochemical operations are still an open question since no protection schemes were developed against adversarial contamination or result-manipulation attacks. Optimization of Trustworthy Biomolecular Quantitative Analysis Using Cyber-Physical Microfluidic Platforms provides solutions to these challenges by introducing a new design flow based on the realistic modeling of contemporary molecular biology protocols. It also presents a microfluidic security flow that provides a high-level of confidence in the integrity of such protocols. In summary, this book creates a new research field as it bridges the technical skills gap between microfluidic systems and molecular biology protocols but it is viewed from the perspective of an electronic/systems engineer.
Optimization of Tuned Mass Dampers: Using Active and Passive Control (Studies in Systems, Decision and Control #432)
by Gebrail Bekdaş Sinan Melih NigdeliThis book is a timely book to summarize the latest developments in the optimization of tuned mass dampers covering all classical approaches and new trends including metaheuristic algorithms. Also, artificial intelligence and machine learning methods are included to predict optimum results by skipping long optimization processes. Another difference and advantage of the book are to provide chapters about several types of control types including passive tuned mass dampers, active tuned mass dampers, tuned liquid dampers, tuned liquid column dampers and inerter dampers. Tuned mass dampers (TMDs) are vibration absorber devices used in all types of mechanic systems. The key factor in the design is an effective tuning of TMDs for the desired performance. In practice, several high-rise structures and bridges were designed by including TMDs. Also, TMDs were installed after the construction of the structures after several negative experiences resulting from the disturbing sway of the structures. In optimum design, several closed-form expressions have been proposed for optimum frequency and damping ratio of TMDs, but the exact optimization requires iterative optimization approaches. The current trend is to use evolutionary algorithms and metaheuristic optimization methods to reach the goal.
Optimization of Unit Operations
by Bela G. LiptakThis comprehensive book examines the technology and practical applications of plant multivariable envelope control. Optimize plant productivity, including air handlers, boilers, chemical reactors, chillers, clean-rooms, compressors and fans, cooling towers, heat exchangers, and pumping stations.Béla G. Lipták speaks on Post-Oil Energy Technology on the AT&T Tech Channel.
Optimization of Urban Wastewater Systems using Model Based Design and Control: UNESCO-IHE PhD Thesis
by Carlos Alberto Velez QuinteroA considerable amount of scientific evidence has been collected leading to the conclusion that urban wastewater components should be designed as one integrated system, in order to protect the receiving waters cost-effectively. Moreover, there is a need to optimize the design and operation of the sewerage network and wastewater treatment plant (WwTP) considering the dynamic interactions between them and the receiving waters. This book introduces a method called Model Based Design and Control (MoDeCo) for the optimum design and control of urban wastewater components. The book presents a detailed description of the integration of modelling tools for the sewer, the wastewater treatment plants and the rivers. The complex modelling structure used for the integrated model challenge previous applications of integrated modelling approaches presented in scientific literature. The combination of modelling tools and multi-objective evolutionary algorithms demonstrated in this book represent an excellent tool for designers and managers of urban wastewater infrastructure. This book also presents two alternatives to solve the computing demand of the optimization of integrated systems in practical applications: the use of surrogate modelling tools and the use of cloud computer infrastructure for parallel computing.
Optimization Techniques and their Applications to Mine Systems
by Amit Kumar Gorai Snehamoy ChatterjeeThis book describes the fundamental and theoretical concepts of optimization algorithms in a systematic manner, along with their potential applications and implementation strategies in mining engineering. It explains basics of systems engineering, linear programming, and integer linear programming, transportation and assignment algorithms, network analysis, dynamic programming, queuing theory and their applications to mine systems. Reliability analysis of mine systems, inventory management in mines, and applications of non-linear optimization in mines are discussed as well. All the optimization algorithms are explained with suitable examples and numerical problems in each of the chapters. Features include:• Integrates operations research, reliability, and novel computerized technologies in single volume, with a modern vision of continuous improvement of mining systems.• Systematically reviews optimization methods and algorithms applied to mining systems including reliability analysis.• Gives out software-based solutions such as MATLAB®, AMPL, LINDO for the optimization problems.• All discussed algorithms are supported by examples in each chapter.• Includes case studies for performance improvement of the mine systems. This book is aimed primarily at professionals, graduate students, and researchers in mining engineering.
Optimization Theory with Applications
by Donald A. PierreOptimization principles are of undisputed importance in modern design and system operation. They can be used for many purposes: optimal design of systems, optimal operation of systems, determination of performance limitations of systems, or simply the solution of sets of equations. While most books on optimization are limited to essentially one approach, this volume offers a broad spectrum of approaches, with emphasis on basic techniques from both classical and modern work.After an introductory chapter introducing those system concepts that prevail throughout optimization problems of all types, the author discusses the classical theory of minima and maxima (Chapter 2). In Chapter 3, necessary and sufficient conditions for relative extrema of functionals are developed from the viewpoint of the Euler-Lagrange formalism of the calculus of variations. Chapter 4 is restricted to linear time-invariant systems for which significant results can be obtained via transform methods with a minimum of computational difficulty. In Chapter 5, emphasis is placed on applied problems which can be converted to a standard problem form for linear programming solutions, with the fundamentals of convex sets and simplex technique for solution given detailed attention. Chapter 6 examines search techniques and nonlinear programming. Chapter 7 covers Bellman's principle of optimality, and finally, Chapter 8 gives valuable insight into the maximum principle extension of the classical calculus of variations.Designed for use in a first course in optimization for advanced undergraduates, graduate students, practicing engineers, and systems designers, this carefully written text is accessible to anyone with a background in basic differential equation theory and matrix operations. To help students grasp the material, the book contains many detailed examples and problems, and also includes reference sections for additional reading.
Optimization Using Evolutionary Algorithms and Metaheuristics: Applications in Engineering (Science, Technology, and Management)
by Kaushik Kumar J. Paulo DavimMetaheuristic optimization is a higher-level procedure or heuristic designed to find, generate, or select a heuristic (partial search algorithm) that may provide a sufficiently good solution to an optimization problem, especially with incomplete or imperfect information or limited computation capacity. This is usually applied when two or more objectives are to be optimized simultaneously. This book is presented with two major objectives. Firstly, it features chapters by eminent researchers in the field providing the readers about the current status of the subject. Secondly, algorithm-based optimization or advanced optimization techniques, which are applied to mostly non-engineering problems, are applied to engineering problems. This book will also serve as an aid to both research and industry. Usage of these methodologies would enable the improvement in engineering and manufacturing technology and support an organization in this era of low product life cycle. Features: Covers the application of recent and new algorithms Focuses on the development aspects such as including surrogate modeling, parallelization, game theory, and hybridization Presents the advances of engineering applications for both single-objective and multi-objective optimization problems Offers recent developments from a variety of engineering fields Discusses Optimization using Evolutionary Algorithms and Metaheuristics applications in engineering
Optimization with LINGO-18: Problems and Applications
by Irfan Ali Neha GuptaThis book presents fundamental concepts of optimization problems and its real-world applications in various fields. The core concepts of optimization, formulations and solution procedures of various real-world problems are provided in an easy-to-read manner. The unique feature of this book is that it presents unified knowledge of the modelling of real-world decision-making problems and provides the solution procedure using the appropriate optimization techniques. The book will help students, researchers, and faculty members to understand the need for optimization techniques for obtaining optimal solution for the decision-making problems. It provides a sound knowledge of modelling of real-world problems using optimization techniques. It is a valuable compendium of several optimization techniques for solving real-world application problems using optimization software LINGO. The book is useful for academicians, practitioners, students and researchers in the field of OR. It is written in simple language with a detailed explanation of the core concepts of optimization techniques. Readers of this book will understand the formulation of real-world problems and their solution procedures obtained using the appropriate optimization techniques.
Optimizations and Programming: Linear, Non-linear, Dynamic, Stochastic and Applications with Matlab
by Abdelkhalak El Hami Bouchaib RadiThis book is a general presentation of complex systems, examined from the point of view of management. There is no standard formula to govern such systems, nor to effectively understand and respond to them. The interdisciplinary theory of self-organization is teeming with examples of living systems that can reorganize at a higher level of complexity when confronted with an external challenge of a certain magnitude. Modern businesses, considered as complex systems, ideally know how to flexibly and resiliently adapt to their environment, and also how to prepare for change via self-organization. Understanding sources of potential crisis is essential for leaders, though not all crises are necessarily bad news, as creative firms know how to respond to challenges through innovation: new products and markets, organizational learning for collective intelligence, and more.
Optimized Engineering Vibration Isolation, Absorption and Control (Springer Tracts in Civil Engineering)
by Wei Huang Jian XuThis book presents the research results of advanced vibration control technology, based on two types of typical equipment in industrial engineering of China: power equipment and vibration-sensitive equipment. The main contents of this book include optimized active control strategy research, semi-active control research that can track and equivalently achieve active control effects, refined analysis of active control based on finite element method, research on the impact of vibration isolator layout on vibration isolation performance, passive and active control research based on system freedom decoupling and load decoupling, realized passive and active control research using quasi-zero stiffness system based on positive and negative stiffness, intelligent sensors optimization deployment of plane and space structure, and related key technology application cases in engineering applications. This book provides useful references for engineers and researchers in industrial engineering and technical support for practitioners in the development of China's high-end industry.
Optimizing Engineering Problems through Heuristic Techniques (Science, Technology, and Management)
by J. Paulo Davim Kaushik Kumar Divya ZindaniThis book will cover heuristic optimization techniques and applications in engineering problems. The book will be divided into three sections that will provide coverage of the techniques, which can be employed by engineers, researchers, and manufacturing industries, to improve their productivity with the sole motive of socio-economic development. This will be the first book in the category of heuristic techniques with relevance to engineering problems and achieving optimal solutions. Features Explains the concept of optimization and the relevance of using heuristic techniques for optimal solutions in engineering problems Illustrates the various heuristics techniques Describes evolutionary heuristic techniques like genetic algorithm and particle swarm optimization Contains natural based techniques like ant colony optimization, bee algorithm, firefly optimization, and cuckoo search Offers sample problems and their optimization, using various heuristic techniques
Optimizing Liner Shipping Fleet Repositioning Plans
by Kevin TierneyThis monograph addresses several critical problems to the operations of shipping lines and ports, and provides algorithms and mathematical models for use by shipping lines and port authorities for decision support. One of these problems is the repositioning of container ships in a liner shipping network in order to adjust the network to seasonal shifts in demand or changes in the world economy. We provide the first problem description and mathematical model of repositioning and define the liner shipping fleet repositioning problem (LSFRP). The LSFRP is characterized by chains of interacting activities with a multi-commodity flow over paths defined by the activities chosen. We first model the problem without cargo flows with a variety of well-known optimization techniques, as well as using a novel method called linear temporal optimization planning that combines linear programming with partial-order planning in a branch-and-bound framework. We then model the LSFRP with cargo flows, using several different mathematical models as well as two heuristic approaches. We evaluate our techniques on a real-world dataset that includes a scenario from our industrial collaborator. We show that our approaches scale to the size of problems faced by industry, and are also able to improve the profit on the reference scenario by over US$14 million.
Optimizing Metabolic Status for the Hospitalized Patient: The Role of Macro- and Micronutrition on Disease Management
by Michael M. Rothkopf, MD, FACP, FACN Jennifer C. JohnsonThis book is a guide for clinicians seeking to use metabolic approaches in the care of hospitalized patients. Since a nutritional component exists for practically any disease process managed, it is important to properly address the macro- and micronutrient issues that can help facilitate a favourable clinical outcome. Metabolic medicine is a newly recognized speciality that applies proven nutritional approaches to support hospitalized patients within existing standards of care. Optimizing Metabolic Status for the Hospitalized Patient: The Role of Macro- and Micronutrition on Disease Management addresses the gap of nutrition knowledge among physicians who generally care for patients without addressing the nutritional and metabolic perspective. Features: · State-of-the-art guidelines for practicing metabolic medicine in the hospital setting. · “Hands on” guide for day-to-day metabolic management of hospitalized patients. · Personal insights from one of the field’s leading practitioners, drawing upon decades of experience. · Historical reviews of key scientific developments. This book is written by Dr Michael M. Rothkopf, Clinical Professor of Medicine at Rutgers/New Jersey Medical School. Dr Rothkopf founded the Metabolic Medicine Center at Morristown Medical Center and is the current Metabolic Medicine Consultant for the Heart Transplant, Lung Transplant, Cardiac Surgery and Wound Care Programs at RWJBH/Newark Beth Israel Medical Center. This book is directed at the physician level of hospital care. It provides value to a broad range of physicians regardless of their medical specialty or subspecialty. It will also be useful for medical students and resident physicians in training as well as nurse practitioners and physician assistants working in hospital settings.
Optimizing Project Management
by Te WuSHELVING GUIDE: Project Management This hands-on guide is written for project professionals seeking to find an optimized way of performing project management. It provides answers to such critical questions as: Why should an organization apply project management? What is the value of project management in the broader context of an organization? Is project management as successful as some advocates suggested or is it a waste of time and resources because of the many extensive and bureaucratic processes? Which project management approach should our project team adopt: predictive or adaptive, waterfall or rolling water, extreme programming or Scrum? This book aims to provide an optimized view of project management by balancing and blending competing methodologies (e.g., traditional versus Agile), lengthy methodologies and broad principles, processes and practices, and the need to understand versus the need to apply. It includes project management templates, an integrated case study illustrating how to apply tools and concepts, and a glossary of key terms. Optimizing Project Management is for both aspiring and practicing project management professionals. It covers the core concepts, practices, and skills that are useful for developing new ideas, planning activities, implementing projects, and conducting planning and controlling of schedule, budget, and scope. The text is particularly useful for students, project professionals wanting to refresh their knowledge, and those pursuing project management certifications. This book is aligned with common project management standards such as the Project Management Body of Knowledge and the ISO 21502: Project, Programme and Portfolio Management — Guidance on Project Management.
Optimizing Project Work, Management, and Delivery
by Gary L. Richardson Brad M. JacksonThousands of project management–related books have been written. Why is Optimizing Project Work, Management, and Delivery different? This book represents the authors’ experiences gained from looking at the problem of project management for 50 years and wondering why projects cannot be more successful. Experience from various management models and techniques has helped but still does not fit reality or provide accurate forecasts. Industry surveys have compiled the root causes of project failure, and yet they persist. Is there no answer to this problem? As the book explains, the management solution is not in the models or the theory but is found in how they are mapped against the actual target project characteristics. This is the book’s unique strength. There are major coverage gaps in current project management models that also need to be recognized. All of the existing models are correct in some ways, and yet each is also wrong. The book starts by reviewing popular models and related topics that help construct the building blocks of an integrated model structure, which is at the core of this book. The integrated model described here is meant to be a decision-oriented view related to the project life cycle rather than a cookbook of success steps. Project management is too complex for a cookbook approach. This text helps managers find that right path.
Optimizing Small Multi-Rotor Unmanned Aircraft: A Practical Design Guide
by Stephen PriorThis design guide was written to capture the author’s practical experience of designing, building and testing multi-rotor drone systems over the past decade. The lack of one single source of useful information meant that the past 10 years has been a steep learning curve, a lot of self-tuition and many trial and error tests. Lessons learnt the hard way are not always the best way to learn. This book will be useful for the amateur drone pilot who wants to build their own system from first principles, as well as the academic researcher investigating novel design concepts and future drone applications.
Optimizing Stormwater Treatment Practices
by Andrew J. Erickson John S Gulliver Peter T WeissOptimizing Stormwater Treatment Practices: A Handbook of Assessment and Maintenance provides the information necessary for developing and operating an effective maintenance program for stormwater treatment. The book offers instructions on how to measure the level of performance of stormwater treatment practices directly and bases proposed maintenance schedules on actual performance and historical maintenance efforts and costs. The inspection methods, which are proven in the field and have been implemented successfully, are necessary as regulatory agencies are demanding evaluations of the performance of stormwater treatment practices. The authors have developed a three-tiered approach that offers readers a standard protocol for how to determine the effectiveness of stormwater treatment practices currently in place.
Optimizing the Operation of a Multiple Reservoir System in the Eastern Nile Basin Considering Water and Sediment Fluxes (IHE Delft PhD Thesis Series)
by Reem Fikri DignaThe Eastern Nile riparian countries Egypt, Ethiopia and Sudan are currently developing several reservoir projects to contribute to the needs for energy and food production in the region. The Nile Basin, particularly the Eastern Nile Sub-basin, is considered one of a few international river systems with potential conflicts between riparian countries. In the absence of formal mechanisms for collaboration, the transboundary nature of this basin makes sound water resources development challenging. The large seasonal and inter-annual variability of the river flow exacerbates those challenges. A further complication is the high sediment load in the Eastern Nile rivers during the high flow season. This study contributes to fill relevant knowledge gaps through a better understanding of the methods needed for a complex system of multipurpose reservoirs, considering both water quantity and sediment load. The study quantifies the impacts of water resources development in the Eastern Nile basin and identifies system management options at both regional and country level. Developing a collaborative and unified perspective of the countries towards new projects can be beneficial for all. New operation rules are proposed for improving operation of the current system when new infrastructures are developed and operated either unilaterally or, ideally, cooperatively.
Optimizing U.S. Air Force and Department of Defense Review of Air Force Acquisition Programs
by National Research Council of the National AcademiesThe Department of Defense (DOD) spends over $300 billion each year to develop, produce, field and sustain weapons systems (the U.S. Air Force over $100 billion per year). DOD and Air Force acquisitions programs often experience large cost overruns and schedule delays leading to a loss in confidence in the defense acquisition system and the people who work in it. Part of the DOD and Air Force response to these problems has been to increase the number of program and technical reviews that acquisition programs must undergo. This book looks specifically at the reviews that U.S. Air Force acquisition programs are required to undergo and poses a key question: Can changes in the number, content, or sequence of reviews help Air Force program managers more successfully execute their programs? This book concludes that, unless they do it better than they are now, Air Force and DOD attempts to address poor acquisition program performance with additional reviews will fail. This book makes five recommendations that together form a gold standard for conduct of reviews and if implemented and rigorously managed by Air Force and DOD acquisition executives can increase review effectiveness and efficiency. The bottom line is to help program managers successfully execute their programs.
Optimum Cooling of Data Centers
by Jun Dai Michael M. Ohadi Diganta Das Michael G. PechtThis book describes the use of free air cooling to improve the efficiency of, and cooling of, equipment for use in telecom infrastructures. Discussed at length is the cooling of communication installation rooms such as data centers or base stations, and this is intended as a valuable tool for the people designing and manufacturing key parts of communication networks. This book provides an introduction to current cooling methods used for energy reduction, and also compares present cooling methods in use in the field. The qualification methods and standard reliability assessments are reviewed, and their inability to assess the risks of free air cooling is discussed. The method of identifying the risks associated with free air cooling on equipment performance and reliability is introduced. A novel method of assessment for free air cooling is also proposed that utilizes prognostics and health management (PHM). This book also: Describes how the implementation of free air cooling can save energy for cooling within the telecommunications infrastructure. Analyzes the potential risks and failures of mechanisms possible in the implementation of free air cooling, which benefits manufacturers and equipment designers. Presents prognostics-based assessments to identify and mitigate the risks of telecommunications equipment under free air cooling conditions, which can provide the early warning of equipment failures at operation stage without disturbing the data centers' service. Optimum Cooling for Data Centers is an ideal book for researchers and engineers interested in designing and manufacturing equipment for use in telecom infrastructures.
Optimum Design and Manufacture of Wood Products
by Jegatheswaran Ratnasingam Endre Magoss Zsolt Kovács Etele CsanádyThis monograph presents state-of-the-art knowledge in wood manufacturing design with a special focus on the elaboration of functional relationships. The authors transfer and apply the method of functional relationships to challenges in wood manufacturing, and the book contains many worked examples which help the reader to better understand the presented method. The topical spectrum includes machining processes, energy consumption, surface quality, hardness and durability properties as well as aesthetical properties. The target audience primarily comprises research experts and practitioners in wood manufacturing, but the book may also be beneficial for graduate students alike.
Optinformatics in Evolutionary Learning and Optimization (Adaptation, Learning, and Optimization #25)
by Liang Feng Yaqing Hou Zexuan ZhuThis book provides readers the recent algorithmic advances towards realizing the notion of optinformatics in evolutionary learning and optimization. The book also provides readers a variety of practical applications, including inter-domain learning in vehicle route planning, data-driven techniques for feature engineering in automated machine learning, as well as evolutionary transfer reinforcement learning. Through reading this book, the readers will understand the concept of optinformatics, recent research progresses in this direction, as well as particular algorithm designs and application of optinformatics. Evolutionary algorithms (EAs) are adaptive search approaches that take inspiration from the principles of natural selection and genetics. Due to their efficacy of global search and ease of usage, EAs have been widely deployed to address complex optimization problems occurring in a plethora of real-world domains, including image processing, automation of machine learning, neural architecture search, urban logistics planning, etc. Despite the success enjoyed by EAs, it is worth noting that most existing EA optimizers conduct the evolutionary search process from scratch, ignoring the data that may have been accumulated from different problems solved in the past. However, today, it is well established that real-world problems seldom exist in isolation, such that harnessing the available data from related problems could yield useful information for more efficient problem-solving. Therefore, in recent years, there is an increasing research trend in conducting knowledge learning and data processing along the course of an optimization process, with the goal of achieving accelerated search in conjunction with better solution quality. To this end, the term optinformatics has been coined in the literature as the incorporation of information processing and data mining (i.e., informatics) techniques into the optimization process. The primary market of this book is researchers from both academia and industry, who are working on computational intelligence methods and their applications. This book is also written to be used as a textbook for a postgraduate course in computational intelligence emphasizing methodologies at the intersection of optimization and machine learning.
Options for Meeting the Maintenance Demands of Active Associate Flying Units
by Robert S. Tripp James M. Masters Kristin F. Lynch John G. Drew Charles Robert RollRAND developed a methodology to help understand and explain the differences between U.S. Air National Guard and active component aircraft maintenance productivity. This research focuses on maintenance options for supporting associate units, where the goal of the associate unit is to produce trained pilots in the most efficient manner possible.
Options to Increase Access to Telecommunications Services in Rural and Low-Income Areas
by Juan Navas-Sabater Arturo Muente-KunigamiTelecommunications sector policy-makers and regulators have a wide range of instruments available to them that can be used to increase access to telecommunications services in rural and low-income areas. The paper provides a review of these instruments, evaluating them against a set of criteria. It then goes on to identify a number of them that are worthy of further consideration by policy-makers and regulators while demonstrating that the effectiveness of the identified instruments can be greatly enhanced by the establishment of a conducive legal, regulatory and institutional framework. The paper concludes by confirming that while no single instrument taken in isolation can provide a full solution to universal access, a mix of the measures identified can be devised to achieve specific policy objectives in a particular country environment.
Opto-Mechanical Systems Design, Volume 1: Design and Analysis of Opto-Mechanical Assemblies (Optical Science And Engineering Ser.)
by Paul Yoder and Daniel VukobratovichOpto-Mechanical Systems Design, Fourth Edition is different in many ways from its three earlier editions: coauthor Daniel Vukobratovich has brought his broad expertise in materials, opto-mechanical design, analysis of optical instruments, large mirrors, and structures to bear throughout the book; Jan Nijenhuis has contributed a comprehensive new chapter on kinematics and applications of flexures; and several other experts in special aspects of opto-mechanics have contributed portions of other chapters. An expanded feature—a total of 110 worked-out design examples—has been added to several chapters to show how the theory, equations, and analytical methods can be applied by the reader. Finally, the extended text, new illustrations, new tables of data, and new references have warranted publication of this work in the form of two separate but closely entwined volumes. This first volume, Design and Analysis of Opto-Mechanical Assemblies, addresses topics pertaining primarily to optics smaller than 50 cm aperture. It summarizes the opto-mechanical design process, considers pertinent environmental influences, lists and updates key parameters for materials, illustrates numerous ways for mounting individual and multiple lenses, shows typical ways to design and mount windows and similar components, details designs for many types of prisms and techniques for mounting them, suggests designs and mounting techniques for small mirrors, explains the benefits of kinematic design and uses of flexures, describes how to analyze various types of opto-mechanical interfaces, demonstrates how the strength of glass can be determined and how to estimate stress generated in optics, and explains how changing temperature affects opto-mechanical assemblies.