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Anticancer Plants: Volume 4

by Mohd Sayeed Akhtar Mallappa Kumara Swamy

This book summarizes the application of plant derived anticancer compounds as chemopreventives to treat several cancer types, focusing on the molecular mechanisms of action of phytocompounds and providing an overview of the basic processes at the cellular and molecular level that are involved in the progression of the cancer and can be employed in targeted preventive therapies. In addition, it highlights the development of novel anticancer drugs from plant sources using bioinformatics approaches. The compiled chapter data aids readers understanding of issues related to bioavailability, toxic effects and mechanisms of action of phytocompounds, and helps them identify the leads and utilize them against various cancer types effectively. Furthermore, it promotes the use of bioinformatics tools in medicinal plants to expedite their use in plant breeding programs to develop molecular markers to distinguish disease subtypes and predicting mutation, which in turn improves cancer diagnosis and prognosis, and to develop new lead compounds computationally. The book provides scientific verifications of plant compounds mechanisms of action against various cancers and offers useful information for students, teachers, and healthcare professionals involved in drug discovery, and clinical and therapeutic research.

Anticancer plants: Volume 1

by Mohd Sayeed Akhtar Mallappa Kumara Swamy

Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types.The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities.Anticancer plants: Volume 1, Properties and Application is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners.

Anticipating Future Business Trends: Volume 1 (Studies in Systems, Decision and Control #535)

by Rim El Khoury

In an age marked by swift technological advancements, businesses find themselves amid unparalleled challenges and opportunities. "Future Business: Anticipating Technological Trends" aims to deliver a comprehensive exploration of the dynamic technological landscape and its profound impact on the business world. This groundbreaking book intends to serve as an invaluable guide for entrepreneurs, business leaders, and innovators, providing them with the tools to anticipate and harness emerging technological trends for a competitive edge in the global market. This book represents a pioneering exploration at the confluence of technology and business evolution. In a time where everything is turning digital, the book strives to empower business leaders, entrepreneurs, and professionals with the knowledge and insights essential for navigating the ever-shifting terrain of technology and its influence on the future of business. This book sets the tone by emphasizing the critical role of technology in shaping the future of business. It will highlight the rapid pace of technological advancements and their far-reaching implications, setting the stage for a deep dive into the key trends that will define the future of business. "Future Business: Anticipating Technological Trends" promises to be an indispensable guide for those seeking to stay ahead in the competitive world of business. By providing actionable insights and strategic foresight, this book aims to empower readers to harness the full potential of emerging technologies for sustainable business success.

Anticipating Future Business Trends: Volume 2 (Studies in Systems, Decision and Control #536)

by Rim El Khoury

In an age marked by swift technological advancements, businesses find themselves amidst unparalleled challenges and opportunities. This book aims to deliver a comprehensive exploration of the dynamic technological landscape and its profound impact on the business world. This groundbreaking book intends to serve as an invaluable guide for entrepreneurs, business leaders, and innovators, providing them with the tools to anticipate and harness emerging technological trends for a competitive edge in the global market. This book represents a pioneering exploration at the confluence of technology and business evolution. In a time where everything is turning digital, the book strives to empower business leaders, entrepreneurs, and professionals with the knowledge and insights essential for navigating the ever-shifting terrain of technology and its influence on the future of business. This book sets the tone by emphasizing the critical role of technology in shaping the future of business. It highlights the rapid pace of technological advancements and their far-reaching implications, setting the stage for a deep dive into the key trends that will define the future of business. This book promises to be an indispensable guide for those seeking to stay ahead in the competitive world of business. By providing actionable insights and strategic foresight, this book aims to empower readers to harness the full potential of emerging technologies for sustainable business success.

The Anticipation of Converging Industries

by Clive-Steven Curran

The blurring of boundaries between hitherto distinct scientific disciplines, technologies or markets is a common and powerful phenomenon. Subjects of this convergence often change consumer behaviours, favouring products and platforms with multiple functions. The Anticipation of Converging Industries provides a detailed focus on the triggers, drivers and consequences of convergence to create a more concise definition of convergence. This detailed analysis includes a specifically developed toolbox for 'convergence foresight', creating a forecasting method for convergence trends. With the focus on the chemical, biotechnological and pharmaceutical industries, several indicators of convergence in the areas of Nutraceuticals/Functional Foods, Cosmeceuticals and ICT are derived from samples including over 1million patents and scientific publications. By supporting this methodical approach with real world data, The Anticipation of Converging Industries is perfect for industry practitioners looking for a competitive edge in the present and for the future. Similarly, academics will find a comprehensive theoretical concept for better understanding the underlying rationale of convergence at their disposal

Anticipatory Ethics and The Use of CRISPR in Humans

by Michael W. Nestor Richard L. Wilson

The future of gene editing in humans will involve the use of CRISPR. How we think about the combination of the scientific, ethical, and moral aspects of this technology is paramount to the success or failure of CRISPR in humans. Unfortunately, the current scientific discussion around CRISPR in humans has left ethics trailing behind due to the rapid pace of innovation. New modes of ethics and stakeholder participation are needed to keep pace with rapid scientific advances and provide the necessary policy and ethical frameworks necessary to help CRISPR flourish as an important health care tool to treat human disease. This requires intense interdisciplinary collaboration and discussion between scientists and philosophers, policymakers and legal scholars, and the public.Dr. Michael W. Nestor (a neuroscientist who actively uses CRISPR in pre-clinical research) and Professor Richard Wilson (a philosopher who focuses on anticipatory ethics) set out to develop a new ethical approach considering the use of CRISPR in human targeted therapies. The field of anticipatory ethics is uniquely poised to tackle questions in fast-evolving technical areas where the pace of innovation outstrips traditional philosophical approaches. Furthermore, because of its “anticipatory” nature, this type of analysis provides the opportunity to look ahead and into the future concerning potential uses of CRISPR in humans, uses that are not currently possible. Nestor and Wilson collaborate both scientifically and philosophically in this book to forecast potential outcomes as the scientific and medical community goes beyond using CRISPR to correct genes that underlie diseases where a single gene is involved. Instead, Nestor and Wilson envision CRISPR in complex, multigenic disorders with a specific focus on the use of CRISPR to edit genes involved in mental traits like IQ or other cognitive characteristics. They argue that the use of CRISPR to modify genes that are potentially important for mental traits represents a particular category for special consideration from scientists, policymakers, the public, and other stakeholders. Nestor and Wilson explain why using CRISPR to alter mental states is very different from treating a disease like cancer by combining the latest scientific advancements with anticipatory ethics and philosophical phenomenology. Their analysis considers the role that mental states play in personhood and the lived experience-as genes that can change mental/cognitive attributes like IQ have wide-ranging effects on the lived experience in ways that are categorically different from other attributes. This book was written to set a non-exhaustive framework for shared understanding and discussion across disciplines and appeal to scientists and non-scientists alike. This appeal is made inclusively, inviting all stakeholders to engage in active dialogue about the appropriate context for using CRISPR and other gene-editing technologies in humans. It provides policy analysis and recommendations for assuring the most inclusive, equitable, and ethically sound use of CRISPR in humans, concerning its positive potential to treat mental conditions like depression, schizophrenia, Alzheimer’s disease, autism, and the potential to induce other cognitive enhancements.

Anticoagulant Rodenticides and Wildlife (Emerging Topics in Ecotoxicology #5)

by John E. Elliott Nico W. van den Brink Richard F. Shore Barnett A. Rattner

Commensal rodents pose health risks and cause substantial damage to property and food supplies. Rats have also invaded islands and pose a serious threat to native wildlife, particularly raptors and seabirds. Estimates of total damage from introduced rats range into the billions of dollars in developed countries. This book aims to provide a state-of-the-art overview of the scientific advancements in the assessment of exposure, effects and risks that currently used rodenticides may pose to non-target organisms in the environment, along with practical guidance for characterization of hazards. This will be discussed in relation to their efficacy, and the societal needs for rodent control, and discussion of risk mitigation and development of alternatives. The flow in the book is planned as: a. introduction and setting the scene b. problem description (risks and effects on non-targets and secondary poisoning, development of resistance) c. ; alternatives, regulation and risk mitigation d. conclusions and recommendations

Antifouling Surfaces and Materials: From Land to Marine Environment

by Feng Zhou

This book reviews the development of antifouling surfaces and materials for both land and marine environments, with an emphasis on marine anti biofouling. It explains the differences and intrinsic relationship between antifouling in land and marine environments, which are based on superhydrophobicity and superhydrophilicity respectively. It covers various topics including biomimetic antifouling and self-cleaning surfaces, grafted polymer brushes and micro/nanostructure surfaces with antifouling properties, as well as marine anti biofouling. Marine anti biofouling includes both historical biocidal compounds (tributyltin, copper and zinc) and current green, non-toxic antifouling strategies. This book is intended for those readers who are interested in grasping the fundamentals and applications of antifouling. Feng Zhou is a professor at the State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences.

Antifreeze Solutions in Home Fire Sprinkler Systems: Antifreeze Solutions In Home Fire Sprinkler Systems (SpringerBriefs in Fire)

by Inc. Code Consultants

Antifreeze Solutions in Home Fire Sprinkler Systems examines the usage of antifreeze solutions in residential sprinklers, and analyzes their effectiveness in controlling a fire condition and aiding in containment. The book also investigates the possibility of a large-scale ignition occurring from solutions of varying mixtures, and proposes the optimal ones for reducing flammability. Antifreeze Solutions in Home Fire Sprinkler Systems is designed for practitioners as a reference guide for handling antifreeze solutions in residential sprinkler systems. Researchers working in a related field will also find the book valuable.

Antifungal Metabolites of Rhizobacteria for Sustainable Agriculture (Fungal Biology)

by R. Z. Sayyed Anjana Singh Noshin Ilyas

Antifungal Metabolites of Rhizobacteria for Sustainable Agriculture focuses on plant health in agro-ecosystems of various economically important cash and food crops with a concern to promote sustainable agriculture. They have emerged as a key organic tool for enhancing yields. In a natural environment the interactions between plants and phytopathogenic fungi are complex and survival requires a development of resistance to plant diseases. Diversity of Plant Growth Promoting Rhizobacteria (PGPR) diversity depends on the nature of root exudates and soil conditions that affect their interaction with host plants. Novel strategies, such as, applying bioactive natural products against the pathogenic fungus are required to control disease sustainably. Various classes of secondary metabolites including lipopeptides, macrolides, alkaloids, terpenoids and phenolics from microorganisms and plants strongly suppress fungal growth and can also be effective in controlling plant diseases both in vitro and in vivo. The modes of actions of some potential antifungal secondary metabolites against pathogenic fungus are also discussed.Eco-friendly fungal species and their metabolites are excellent agents used for regulating various fungal and bacterial phytopathogens and may have tremendous potential for other applications, and play a key role in enhancing plant tolerance to stress. Antifungal Metabolites of Rhizobacteria for Sustainable Agriculture also covers bovine-based formulations used for sustainable production and nutritional security through horticultural crops, thereby addressing the problems associated with malnutrition and under-nutrition encountered by small and marginal farmers, as well as by families facing resource constraints. These techniques can also improve breathable air, drinkable water, and consumable foods. This book addresses the need to mitigate the health problems of people via organic crop production and to improve the socio-economic status of farmers (especially in developing countries), and to revitalize agricultural sustainability.

Antimicrobial and Antiviral Materials: Polymers, Metals, Ceramics, and Applications

by Peerawatt Nunthavarawong Sanjay Mavinkere Rangappa Suchart Siengchin Mathew Thoppil-Mathew

Emerging microbial and viral infections are a serious challenge to health, safety, and economics around the world. Antimicrobial and antiviral technologies are needed to disrupt the progression and replication of bacteria and viruses and to counter their rapidly evolving resistance. This book discusses recent developments in materials science and engineering in combating infectious diseases and explores advances in antimicrobial and antiviral materials, including polymers, metals, and ceramics and their applications in the fight against pathogens. Features • Covers progress in biomimetic antimicrobial and antiviral materials and antimicrobial/antiviral bulk materials and coatings • Describes modern methods for disinfection of biomedical materials against microbial and viral infection resistance, especially for depressing novel coronavirus (COVID-19) • Details methods to improve material properties to have a longer service life in combating infection • Emphasizes chemical, physical, mechanical, tribological, and antimicrobial/antiviral properties • Offers current and future applications of emerging antimicrobial/antiviral technologies This book will be of interest to materials researchers and industry professionals focusing on antimicrobial and antiviral applications.

Antimicrobial/Anti-Infective Materials: Principles and Applications

by Samuel P. Sawan Gurusamy Manivannan

As our consciousness of microbes increases, it appears that our desire to control our interactions with germs also increases in proportion. This is clearly demonstrated by examining the incredible growth in the number and sales volume of consumer products with antimicrobial claims. In the medical field as well, there is much interest in the use of

Antimicrobial Coatings and Modifications on Medical Devices

by Zheng Zhang Victoria E. Wagner

Based on a fundamental understanding of the interaction between bacteria and materials, this timely volume emphasizes the latest research in the antimicrobial interfacial design and provides an invaluable blueprint for improving antimicrobial performance on devices and products. Antimicrobial Coatings and Modifications targets reduction of microbial accumulation on biomedical and industrial materials through changing interfacial characteristics. Applying a viable antimicrobial coating or modification to resist alarming threats is a highly demanding requirement for many medical and engineering applications. Many contemporary books in the area of antimicrobial solution focus on applying antimicrobial agents or materials that can kill bacteria. The volume pays more attention to eliminating bacterial contamination and biofilm formation through surface characteristics with minimized bacterial resistance and environmental impact.

Antimicrobial Polymers

by Maria Jose Ocio Jose Maria Lagaron Amparo Lopez-Rubio

The pioneering guide on the design, processing, and testing of antimicrobial plastic materials and coatingsThe manifestation of harmful microbes in plastic materials used in medical devices and drugs, water purification systems, hospital equipment, textiles, and food packaging pose alarming health threats to consumers by exposing them to many serious infectious diseases. As a result, high demand for intensifying efforts in the R&D of antimicrobial polymers has placed heavy reliance on both academia and industry to find viable solutions for producing safer plastic materials. To assist researchers and students in this endeavor, Antimicrobial Polymers explores coupling contaminant-deterring biocides and plastics--focusing particular attention on natural biocides and the nanofabrication of biocides. Each chapter is devoted to addressing a key technology employed to impart antimicrobial behavior to polymers, including chemical modification of the polymers themselves. A host of relevant topics, such as regulatory matters, human safety, and environmental risks are covered to help lend depth to the book's vital subject matter. In addition, Antimicrobial Polymers:Discusses the design, processing, and testing of antimicrobial plastic materialsCovers interdisciplinary areas of chemistry and microbiologyIncludes applications in food packaging, medical devices, nanotechnology, and coatingsDetails regulations from the U.S. (FDA and EPA) and EU as well as human safety and environmental concernsAchieving cleaner and more effective methods for improving the infection-fighting properties of versatile and necessary plastic materials is a goal that stretches across many scientific fields. Antimicrobial Polymers combines all of this information into one volume, exposing readers to preventive strategies that harbor vast potential for making exposure to polymeric products and surfaces a far less risky undertaking in the future.

Antimicrobial Research and One Health in Africa

by Akebe Luther King Abia Sabiha Yusuf Essack

Antimicrobial resistance is recognised among the world’s most challenging problems. Despite its global spread, Africa, specifically sub-Saharan Africa, is the most affected by this malaise. Poor living conditions and inadequate access to sanitation and potable water supplies are among contributing factors that have influenced a high disease burden on the continent, requiring extensive antimicrobials. Weak health systems and the absence of firm policies further aggravate the problem, as the use of antimicrobials is mostly unregulated. The increasing demand for animal protein to meet the starving populations’ demands has also influenced the use of these antimicrobials, including those banned on other continents, for food animal production. The ripple effect of indiscriminate use in humans and animals is the massive discharge of antimicrobials, their residues, antimicrobial-resistant microorganisms and their associated genes into the environment. This 14-chapter unique masterpiece presents the AMR problem in African, addressing the various compartments of the One Health – humans, animals, and the environment, to illustrate the need for concerted efforts in the fight against AMR, especially in Africa. Authors from the four cardinal points present diverse aspects of AMR in Africa, starting with behavioural and social drivers of AMR in Africa. Antimicrobial stewardship in an African context is also discussed. AMR in humans is presented through studies on antibiotic-resistant neonates and nontyphoidal Salmonella infections and the clinical relevance of the genetics of viral resistance. Topics on AMR in mastitis, biosecurity in animal farming and the linkage between disinfectants and AMR are discussed. The environmental dimension of AMR is discussed, notably in the aquatic environment, and its implication for aquaculture and irrigation and using nanomaterials to treat polluted waters from such environments are highlighted. Finally, Africa’s rich floral diversity is portrayed as an eco-friendly and cost-effective approach to combat AMR. Hopefully, the work presented will spur greater collaboration between scientists, environmental, animal and human health practitioners, the general population, and policymakers to assimilate and implement the One Health approach to combating AMR, rather than working in silos on their various sectors

Antimicrobial Resistance in Agriculture and its Consequences (Current Trends in Antimicrobial Research)

by Arti Gupta Ram Prasad

This book offers comprehensive coverage of all manifestations of resistance in combating infectious diseases and explores advances in antimicrobial resistance in agriculture and their applications in the fight against microbes. It discusses and compares biological, biochemical, and structural aspects of resistance and its evolution. This is a comprehensive tool covering all manifestations of antimicrobial resistance and microbial resistance genes. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. Novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target) molecule, are highly diverse and are covered in great detail.Students, researchers, scientists, practitioners, academics, computational biologists, stakeholders, and policymakers can benefit from using Antimicrobial Resistance in Agriculture and its Consequences as a resource that addresses microbial biotechnology, microbiology, ethnopharmacology, toxicology, medicinal plant products, and all disciplines related to antimicrobial research.Features of the book: Covers antimicrobial resistance in agriculture with up-to-date research Includes recent references on each plausible antimicrobial resistance in agriculture Details the possible spread of antibiotic resistance bacteria from animals to humans Provides several perspectives in the resistance flux with modern agricultural practices Describes the public health impact of the use of antibiotics in agriculture Presents cutting-edge research on epigenetics, nanotechnology, and emergent antimicrobial technologies Outlines recent laws and regulatory guidelines in the federal agency, responsibility, and authority

Antimicrobials for Sustainable Food Storage

by Naga Raju Maddela Jaskiran Kaur García, Gusdanis Alberto Campos

Finding natural substances is worthwhile in food preservation. The principal motivation behind this edited volume, Antimicrobials for Sustainable Food Storage, is to collect and present widespread knowledge in the domain of sustainable food ingredients with antimicrobial properties. The book consists of two sections. The first section of this volume is about food ingredients as antimicrobials, and the second section discusses the recent advances in the applications of food ingredients.Interplay of various environmental factors favors the growth of different microorganisms during the food preservation process. Growth of undesirable microorganisms negatively influences the taste, smell, color, and texture of food. Therefore, sustainable food preservation is a challenging issue. Though several chemicals have emerged, inevitable health effects are commonly encountered by food preserve chemicals.Microbial products (nisin, enterocin, pentosin, sakacin, and pediocin) have immense importance in prolonging the shelf life of food substances by controlling food spoilage and pathogenic microbes. Yeasts and cyanobacteria are also potential candidates in the supply of food ingredients with significant antimicrobial properties. However, limited awareness of antimicrobials as food ingredients and the unavailability of a single source of the latest insights on such food ingredients in one place led to the motivation to produce this work.Key Features: Provides insights on natural antimicrobials in food preservation Underlines the importance of sustainable food packaging Offers knowledge on emerging trends in antimicrobial-based food storage Diverse applications are covered in different chapters. This book covers various antimicrobials as food preservatives, such as metabolites, natural products, essential oils, nanomaterials, L-arginine, polyphenols, phaeophyceae, and horchata. There are also chapters that focus on the applicability and prospective studies of essential oils, edible biofilms, biodegradable antimicrobials, and nanostructured lipid carriers in the food sector and the method for encapsulation of antimicrobials.

Antimicrobials in Agriculture (Current Trends in Antimicrobial Research)

by Ram Prasad Arti Gupta

This book offers comprehensive coverage of all manifestations of resistance in combating infectious diseases and explores advances in antimicrobials in agriculture and their applications in the fight against microbes. According to the World Health Organization, antimicrobial resistance is a major threat to global health because the number of alternative antibiotics is very limited. Antimicrobial resistance is a slow, evolutionary process that has been accelerated by human activities in the health, environment, and agriculture sectors. Due to their wide application, antibiotics and their residues have been found in almost all food products and natural ecosystems. This book appraises the drivers, impact, and mitigation of antimicrobials, with a focus on methods and targets. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. The novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. The underlying molecular mechanisms, which depend not only on the microbe but on the specific drug molecule, are highly diverse and are covered in detail.Students, researchers, scientists, practitioners, academicians, biologists, microbiologists, stakeholders, and policymakers can benefit from current trends in antimicrobials in agriculture that address microbiology, microbial biotechnology, ethnopharmacology, toxicology, natural medicinal plant products, secondary metabolites, and all disciplines related to antimicrobial research.Features of the book: Covers antimicrobials in agriculture with up-to-date research Recent references on plausible antimicrobials in agriculture Public health impact of the use of antibiotics in agriculture Antimicrobial efficacy of medicinal plants Role of phytoalexins in agriculture Nanoparticles as antimicrobial agents Presents cutting-edge research on microbiology, nanotechnology, and emergent antimicrobial technologies

Antimicrobials in Food (Food Science and Technology)

by P. Michael Davidson, T. Matthew Taylor, and Jairus R. D. David

Fifteen years have passed since the 3rd Edition of Antimicrobials in Foods was published. It was arguably considered the "must-have" reference for those needing information on chemical antimicrobials used in foods. In the years since the last edition, the food industry has undergone radical transformations because of changes on several fronts. Reported consumer demands for the use of "natural" and "clean-label" antimicrobials has increased significantly. The discovery of new foodborne pathogen niches and potentially hazardous foods, along with a critical need to reduce food spoilage waste, has increased the need for suitable antimicrobial compounds or systems. Novel natural antimicrobials continue to be discovered and new research has been carried out on traditional compounds. These and other related issues led the editors to develop the 4th Edition of Antimicrobials in Foods. In the 4th Edition, the editors have compiled contemporary topics with information synthesized from internationally recognized authorities in their fields. In addition to updated information, new chapters have been added in this latest release with content on the use of bacteriophages, lauric arginate ester, and various systems for antimicrobial encapsulation and delivery. Comprehensive revisions of landmark chapters in previous editions including naturally occurring antimicrobials from both animal and plant sources, methods for determining antimicrobial activity, new approaches to multifactorial food preservation or "hurdle technology," and mechanisms of action, resistance, and stress adaptation are included. Complementing these topics is new information on quantifying the capability of "clean" antimicrobials for food preservation when compared to traditional food preservatives and industry considerations when antimicrobials are evaluated for use in food manufacture. Key Features: Covers all food antimicrobials, natural and synthetic, with the latest research on each type Contains 5,000+ references on every conceivable food antimicrobial Guides in the selection of appropriate additives for specific food products Innovations in antimicrobial delivery technologies and the use of multifactorial food preservation with antimicrobials are included

Antimicrobials in Livestock 1: A European Perspective

by Lucie Pokludová

This first volume in a two-volume work enhances readers’ understanding of antimicrobial resistance mechanisms in selected bacterial species that cause diseases in major food producing animals. It provides an overview of the current legislation and policies seeking to regulate the authorisation, manufacturing, distribution and use of veterinary antimicrobials in practice in a way that helps to contain the spread of antimicrobial resistance. The focus is put on Europe, without neglecting the global context. Moreover, attention is paid to various uses of antimicrobials in livestock, considering both their risks and benefits, from the distant past to the present. Growth promotion, prophylaxis, metaphylaxis, diagnostics and treatment are discussed not only with regard to food production and animal health, but also considering the One Health concept, which combines public and animal health with environmental aspects. A summary of various systems for monitoring the use of antimicrobials is provided, as well as an overview of the diseases that European veterinarians most often treat with antimicrobials. In closing, the book addresses the complexity of recent measures that are of key importance for antimicrobial stewardship, e.g. biosecurity, vaccination and other preventive tools including the newest technologies like smart farming. The complete two-volume work provides an extensive review of various aspects related to the use of antimicrobials in veterinary medicine, especially considering major food producing species, their most common infectious diseases and causative pathogens, and mainly focusing on the situation in Europe, without ignoring the global context. While Volume I discusses more general aspects of antibiotic use such as regulatory, laboratory and practical issues from different perspectives, Volume II more specifically discusses medical aspects and the use of antimicrobials in cattle, pigs, poultry and horses, as well as pharmacokinetics and pharmacodynamics, two of the most important factors determining the success of treatment. In both volumes, each chapter confronts the reader with open questions to stimulate further discussions and future research on the topics covered.

Antimicrobials in Livestock 2: A European Perspective

by Lucie Pokludová

This second volume of the two-volumes work “Antimicrobials in Livestock” offers an in-depth look at the antimicrobials commonly used in veterinary medical care of the major food producing animals pigs, poultry and cattle as well as horses, bringing to readers’ attention also pharmacokinetic and pharmacodynamic characteristics of these drugs. The individual chapters also provide a brief description of preventive tools as well as alternatives to conventional treatment options that could help minimise the use of antibiotics and combat the problems caused by increasing antimicrobial resistance. The focus is on Europe, without neglecting the global context. The complete two-volumes provide an extensive review of various aspects related to the use of antimicrobials in veterinary medicine. Volume I explores the use of antimicrobials in animals from the regulatory, practical as well scientific perspective and is targeted on EU policies and regulatory surroundings, providing also information on risks linked to the extensive use of antibiotics in livestock and highlighting importance of methods of laboratory testing for susceptibility and resistance, starting from phenotype tests and moving towards genetic analysis results providing molecular biology aspects. Each chapter confronts the reader with open questions to stimulate further discussions and future research on the topics covered. Volume II more specifically discusses medical aspects necessary for targeted, responsible, and evidence-based use of antimicrobials in cattle, pigs, poultry, and horses, as well as pharmacokinetics and pharmacodynamics as two of the most important factors necessary for proper dosing schedule setting of effective treatment. While the preface of the first volume started with questions, Volume II’s preface ends with them, having the intention to provoke more in depth and innovative thinking and might be the start of a new era, which is needed to keep antimicrobials working and available for the future generations both in human and veterinary medicine.

Antimonide-Related Strained-Layer Heterostructures: Theory, Methods, And Applications (Systems Innovation Book Ser.)

by Adedeji B. Badiru

Interest in antimonide-related heterostructures is burgeoning due to their applications as light sources, diode lasers, modulators, filters, switches, nonlinear optics, and field-defect transistors. This volume, featuring contributions from leading researchers in the field, is the first book to focus on antimonide-related topics. It offers to both the beginning student and the advanced researcher a comprehensive review of the state of the art in this exciting new area of research.

Antioxidant Nutraceuticals: Preventive and Healthcare Applications (Nutraceuticals)

by Chuanhai Cao Sarvadaman Pathak Kiran Patil

This book addresses various clinical and sub clinical applications of antioxidant nutraceuticals, with a primary focus on preventive use for general wellness, common ailments, and such chronic illnesses as cancer and neurological applications. This unique book captures the applications of natural antioxidants, which have been used for thousands of years in Traditional Chinese Medicine and Ayurvedic Medicine as well as modern nutraceuticals formulations. It covers antioxidant applications in clinical scenarios including the historical perspective, basic antioxidant properties and applications, anti-inflammatory properties, and antioxidant applications in a variety of clinical conditions.

Antioxidant Polymers

by Giuseppe Cirilo Francesca Iemma

Antioxidant Polymers is an exhaustive overview of the recent developments in the field of polymeric materials showing antioxidant properties. This research area has grown rapidly in the last decade because antioxidant polymers have wide industry applications ranging from materials science to biomedical, pharmaceuticals and cosmetics.

Antioxidant Properties of Spices, Herbs and Other Sources

by Denys J. Charles

The scientific world and modern society today is experiencing the dawning of an era of herbal medicine. Extensive research has shown that aromatic plants are important anti-inflammatory, antioxidant, anti aging and immune boosting delectable foods, with the magic and miracle to boost our immune system providing us with extended and an improved quality of life. Apart from making bland recipes into welcoming or interesting victories, herbs and spices have stirred the minds of the research community to look deeper into its active components from a functional perspective. It is essential to present the scientific and medicinal aspect of herbs and spices together with the analysis of constituents, its medicinal application, toxicology and its physiological effects. Herbs and spices with high levels of antioxidants are in great demand as they tend to promote health and prevent diseases naturally assuring increased safety and reliability for consumers. Herbs and spices are not only known for taste and flavor, but today research has opened up a new realm in which the antioxidant properties of these aromatic plants provide preservation for foods and health benefits for consumers who look forward to concrete scientific research to guide them further and explore herbal medicine. The aim of this book is to create awareness in society about the reliability of medicinal properties of certain herbs and spices through scientific and scholarly research.

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