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Translational Approach to Heart Failure
by Jozef Bartunek Marc VanderheydenThe refined pathophysiologal understanding of the heart failure syndrome together with the surge of new technological advances led to innovative medical and interventional treatment strategies improving the outcome of heart failure patients. However the complex interplay between the clinical presentation and the array of the interventions requires a coordinated multidisciplinary "heart team" approach involving various specialists in the cardiovascular field including clinicians, interventionalists, surgeons and cardiac intensivists. In this book, opinion leaders will review of state-of-the-art management of heart failure with particular emphasis on burning clinical questions and challenges faced by the heart team. New medical and interventional therapies for chronic and acute heart failure are addressed by bridging bench to bedside translation in science and technology into practical clinical application and guidance.
Translational Bioinformatics Applications in Healthcare (Intelligent Signal Processing and Data Analysis)
by Khalid Raza Nilanjan DeyTranslational bioinformatics (TBI) involves development of storage, analytics, and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive, and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview on concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare, including Internet of Things (IoT) potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT images, viroinformatics and viral diseases, and COVID-19–related research. Covers recent technologies such as Blockchain, IoT, and Big data analytics in bioinformatics Presents the role of translational bioinformatic methods in the field of viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and their applications in better healthcare Explores medical image analysis with focus on CT images and novel coronavirus disease detection Aimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics. Khalid Raza is an Assistant Professor, the Department of Computer Science, Jamia Millia Islamia (Central University), New Delhi. His research interests include translational bioinformatics, computational intelligence methods and its applications in bioinformatics, viroinformatics, and health informatics. Nilanjan Dey is an Associate Professor, the Department of Computer Science and Engineering, JIS University, Kolkata, India. His research interests include medical imaging, machine learning, computer-aided diagnosis, and data mining.
Translational Biomedical Informatics
by Bairong Shen Haixu Tang Xiaoqian JiangThis book introduces readers to essential methods and applications in translational biomedical informatics, which include biomedical big data, cloud computing and algorithms for understanding omics data, imaging data, electronic health records and public health data. The storage, retrieval, mining and knowledge discovery of biomedical big data will be among the key challenges for future translational research. The paradigm for precision medicine and healthcare needs to integratively analyze not only the data at the same level - e. g. different omics data at the molecular level - but also data from different levels - the molecular, cellular, tissue, clinical and public health level. This book discusses the following major aspects: the structure of cross-level data; clinical patient information and its shareability; and standardization and privacy. It offers a valuable guide for all biologists, biomedical informaticians and clinicians with an interest in Precision Medicine Informatics.
Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics (Advances in Experimental Medicine and Biology #1168)
by Erika Ruiz-Garcia Horacio Astudillo-de la VegaBeing a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.
Transmedia Archaeology: Storytelling in the Borderlines of Science Fiction, Comics and Pulp Magazines
by Carlos A. Scolari Paolo Bertetti Matthew FreemanIn this book, the authors examine manifestations of transmedia storytelling in different historical periods and countries, spanning the UK, the US and Argentina. It takes us into the worlds of Conan the Barbarian, Superman and El Eternauta, introduces us to the archaeology of transmedia, and reinstates the fact that it's not a new phenomenon.
Transmedia Knowledge for Liberal Arts and Community Engagement: A StudioLab Manifesto (Digital Education and Learning)
by Jon McKenzieThis book sets forth a pedagogy for renewing the liberal arts by combining critical thinking, media activism, and design thinking. Using the StudioLab approach, the author seeks to democratize the social and technical practices of digital culture just as nineteenth century education sought to democratize literacy. This production of transmedia knowledge—from texts and videos to comics and installations—moves students between seminar, studio, lab, and field activities. The book also wrestles with the figure of Plato and the very medium of knowledge to re-envision higher education in contemporary societies, issuing a call for community engagement as a form of collective thought-action.
Transmission, Distribution, and Renewable Energy Generation Power Equipment: Aging and Life Extension Techniques, Second Edition
by Bella H. ChudnovskyThe revised edition presents, extends, and updates a thorough analysis of the factors that cause and accelerate the aging of conductive and insulating materials of which transmission and distribution electrical apparatus is made. New sections in the second edition summarize the issues of the aging, reliability, and safety of electrical apparatus, as well as supporting equipment in the field of generating renewable energy (solar, wind, tide, and wave power). When exposed to atmospheric corrosive gases and fluids, contaminants, high and low temperatures, vibrations, and other internal and external impacts, these systems deteriorate; eventually the ability of the apparatus to function properly is destroyed. In the modern world of "green energy", the equipment providing clean, electrical energy needs to be properly maintained in order to prevent premature failure. The book’s purpose is to help find the proper ways to slow down the aging of electrical apparatus, improve its performance, and extend the life of power generation, transmission, and distribution equipment.
Transmission Electron Microscopy Characterization of Nanomaterials
by Challa S. S. R. KumarThird volume of a 40volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S. S. R. Kumar. This handbook gives a comprehensive overview about Transmission electron microscopy characterization of nanomaterials. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.
Transmission Electron Microscopy in Micro-nanoelectronics (Wiley-iste Ser.)
by Alain ClaverieToday, the availability of bright and highly coherent electron sources and sensitive detectors has radically changed the type and quality of the information which can be obtained by transmission electron microscopy (TEM). TEMs are now present in large numbers not only in academia, but also in industrial research centers and fabs.This book presents in a simple and practical way the new quantitative techniques based on TEM which have recently been invented or developed to address most of the main challenging issues scientists and process engineers have to face to develop or optimize semiconductor layers and devices. Several of these techniques are based on electron holography; others take advantage of the possibility of focusing intense beams within nanoprobes. Strain measurements and mappings, dopant activation and segregation, interfacial reactions at the nanoscale, defect identification and specimen preparation by FIB are among the topics presented in this book. After a brief presentation of the underlying theory, each technique is illustrated through examples from the lab or fab.
Transmission Expansion Planning: The Network Challenges of the Energy Transition
by Sara Lumbreras Hamdi Abdi Andrés RamosThis book presents a panoramic look at the transformation of the transmission network in the context of the energy transition. It provides readers with basic definitions as well as details on current challenges and emerging technologies. In-depth chapters cover the integration of renewables, the particularities of planning large-scale systems, efficient reduction and solution methods, the possibilities of HVDC and super grids, distributed generation, smart grids, demand response, and new regulatory schemes. The content is complemented with case studies that highlight the importance of the power transmission network as the backbone of modern energy systems. This book will be a comprehensive reference that will be useful to both academics and practitioners.
Transmission Grid Security
by Liisa Haarla Mikko Koskinen Ritva Hirvonen Pierre-Etienne LabeauIn response to the growing importance of power system security and reliability, Transmission Grid Security proposes a systematic and probabilistic approach for transmission grid security analysis. The analysis presented uses probabilistic safety assessment (PSA) and takes into account the power system dynamics after severe faults. In the method shown in this book the power system states (stable, not stable, system breakdown, etc.) are connected with the substation reliability model. In this way it is possible to: estimate the system-wide consequences of grid faults; identify a chain of events that might lead to blackout; and rank the importance of different substation components at the system level. Transmission Grid Security also presents the main features and basic mathematics of PSA. It provides the reader with up-to-date knowledge of the regulatory issues affecting the security of transmission grids in Europe. Transmission Grid Security gives a practical method for the security analysis of transmission grids, making it a valuable text for engineers and system operators, as well as postgraduate students. It includes basic information and detailed modules for creating a reliability model that takes into account all the basic operations and components needed after grid faults.
Transmission Line Matrix (TLM) Techniques for Diffusion Applications
by Donard deCoganTransmission Line Matrix (TLM) is a numerical technique which is based upon establishing an analogue between a space and time dependent physical problem and an electrical network which includes transmission lines. By their very nature these enforce time discretization on the network which can then be solved explicitly in the time-domain. Although it is best known in electromagnetic applications, TLM can also be used to model diffusion phenomena, and this book outlines the state of the art in this area. The first part of the book deals with theory and techniques. The second part is devoted to the development of algorithms for specific applications. This is arranged as a historical sequence starting with heat-flow and matter diffusion. The remainder of the book outlines many of the ingenious exploitations of the unique properties of TLM, including topics such as the solution of convection, Poisson, Laplace, and time-dependent Schrodinger equations. Applications in the firing of ceramics, chromatography, image processing, and the solution of inverse thermal problems are also covered.
Transmission Lines
by Richard CollierThis rigorous treatment of transmission lines presents all the essential concepts in a clear and straightforward manner. Key principles are demonstrated by numerous practical worked examples and illustrations, and complex mathematics is avoided throughout. Early chapters cover pulse propagation, sinusoidal waves and coupled lines, all set within the context of a simple lossless equivalent circuit. Later chapters then develop this basic model by demonstrating the derivation of circuit parameters, and the use of Maxwell's equations to extend this theory to major transmission lines. Finally, a discussion of photonic concepts and properties provides valuable insights into the fundamental physics underpinning transmission lines. Covering DC to optical frequencies, this accessible text is an invaluable resource for students, researchers and professionals in electrical, RF and microwave engineering.
Transmission Lines and Wave Propagation
by Philip C. Magnusson Andreas Weisshaar Vijai K. Tripathi Gerald C. AlexanderTransmission Lines and Wave Propagation, Fourth Edition helps readers develop a thorough understanding of transmission line behavior, as well as their advantages and limitations. Developments in research, programs, and concepts since the first edition presented a demand for a version that reflected these advances. Extensively revised, the fourth edition of this bestselling text does just that, offering additional formulas and expanded discussions and references, in addition to a chapter on coupled transmission lines. What Makes This Text So Popular?The first part of the book explores distributed-circuit theory and presents practical applications. Using observable behavior, such as travel time, attenuation, distortion, and reflection from terminations, it analyzes signals and energy traveling on transmission lines at finite velocities. The remainder of the book reviews the principles of electromagnetic field theory, then applies Maxwell's equations for time-varying electromagnetic fields to coaxial and parallel conductor lines, as well as rectangular, circular, and elliptical cylindrical hollow metallic waveguides, and fiber-optic cables. This progressive organization and expanded coverage make this an invaluable reference. With its analysis of coupled lines, it is perfect as a text for undergraduate courses, while graduate students will appreciate it as an excellent source of extensive reference material. This Edition Includes: An overview of fiber optic cables emphasizing the principle types, their propagating modes, and dispersion Discussion of the role of total internal reflection at the core/cladding interface, and the specific application of boundary conditions to a circularly symmetrical propagating mode A chapter on coupled transmission lines, including coupled-line network analysis and basic crosstalk study More information on pulse propagation on lines with skin-effect losses A freeware program available online Solutions manual available with qualifying course adoption
Transmission Network Investment in Liberalized Power Markets (Lecture Notes in Energy #79)
by Mohammad Reza Hesamzadeh Juan Rosellón Ingo VogelsangThis book provides a systematic overview of transmission network investment in liberalized power markets. Recent government policies to increase the share of intermittent renewable power generation and other technological innovations present new theoretical as well as practical challenges for transmission investments. Written by experts with a background in both economics and engineering, the book examines the economic and technical fundamentals of regulated and merchant transmission investment, and includes case studies of transmission investment in a number of countries. The book is divided into four parts: Part 1 introduces the basic economics and engineering of transmission network investment, while Part 2 discusses merchant investment in the transmission network. Part 3 then examines transmission investment coordination and smart grids, and lastly, Part 4 describes practical experiences of transmission network investment in power market in various countries.
Transmission Network Protection: Theory and Practice
by YeshwantG. PaithankarFrom the basic fundamentals and principles of protective relaying to current research areas in protective systems and future developments in the field, this work covers all aspects of power system protection. It includes the implementation of relays using electromechanical devices, static devices and microprocessors; distance protection of high voltage and extra high voltage lines, including distance relay errors; and adaptive, dynamic, travelling wave and noise-based relays.
Transmission of Electrical Energy: Overhead Lines
by Ailson P. Moura Adriano Aron Moura Ednardo P. RochaTransmission of Electrical Energy: Overhead Lines takes a computational approach through the use of the Alternative Transient Program (ATPdraw), which is a program of worldwide use. The number of exercises solved, including computer simulations with ATPdraw and source codes in MATLAB® make the work didactic and easy to assimilate, even for those readers new to the subject. The subjects presented throughout the text aims to make the reader understand and gain sufficient knowledge to analyze the operation of overhead transmission lines in a steady-state and in a transient state, besides carrying out an introductory project of a steady-state transmission line. The book can be used in both undergraduate and graduate courses in electrical engineering.
Transmission Techniques for 4G Systems
by Mario Marques da Silva Americo Correia Rui Dinis Nuno Souto Joao Carlos SilvaFourth Generation (4G) wireless communication systems support current and emergent multimedia services such as mobile TV, social networks and gaming, high-definition TV, video teleconferencing, and messaging services. These systems feature the All-over-IP concept and boast improved quality of service. Several important R&D activities are curren
Transmissions and Drivetrain Design (Commercial Vehicle Technology)
by Michael HilgersThe aim of this work, consisting of 9 individual, self-contained booklets, is to describe commercial vehicle technology in a way that is clear, concise and illustrative. Compact and easy to understand, it provides an overview of the technology that goes into modern commercial vehicles. Starting from the customer's fundamental requirements, the characteristics and systems that define the design of the vehicles are presented knowledgeably in a series of articles, each of which can be read and studied on their own. This volume, Transmissions and Drivetrain Design, begins with an explanation of how driving resistance and the engine characteristics factor into the configuration of the transmission and transmission ratios. The transmission and its associated assemblies are presented in detail, providing a clear understanding for training and practical applications. Other components of the drivetrain such as the propeller shaft, the clutch and the retarder are also discussed.
Transmissions and Drivetrain Design (Commercial Vehicle Technology)
by Michael Hilgers Wilfried AchenbachThe aim of this work, consisting of 9 individual, self-contained booklets, is to describe commercial vehicle technology in a way that is clear, concise and illustrative. Compact and easy to understand, it provides an overview of the technology that goes into modern commercial vehicles. Starting from the customer's fundamental requirements, the characteristics and systems that define the design of the vehicles are presented knowledgeably in a series of articles, each of which can be read and studied on their own. This volume, Transmissions and Drivetrain Design, begins with an explanation of how driving resistance and the engine characteristics factor into the configuration of the transmission and transmission ratios. The transmission and its associated assemblies are presented in detail, providing a clear understanding for training and practical applications. Other components of the drivetrain such as the propeller shaft, the clutch and the retarder are also discussed.
Transmittierender Faraday-Effekt-Stromsensor (essentials)
by Reiner ThieleReiner Thiele zeigt die Lösung auf, wie die Messung von hohen elektrischen Strömen ohne Eingriff in den Messgrößenkreis gelingt - ein grundsätzliches Problem der elektrischen Energietechnik. Er schlägt dies durch die Applikation des Faraday-Effektes zur Polarisations-Ebenen-Drehung linear polarisierten Lichts in Lichtwellenleitern vor, induziert durch das den stromführenden elektrischen Leiter umgebende Magnetfeld. Eine in Transmission arbeitende erfindungsgemäße Schaltungsanordnung aus optischen und elektronischen Komponenten stellt dabei den gewünschten linearen Zusammenhang zwischen Messgröße und Messwert bei Elimination der störenden Doppelbrechung der Lichtwellenleiter her, die sich ansonsten vermindernd auf die Effizienz des Faraday-Effektes auswirkt.
Transnational Higher Education in Computing Courses: Experiences and Reflections
by Jenny Carter Clive RosenThere has been exponential growth in transnational education (TNE) in the last few years as UK universities have looked to expand their markets. Recipient countries have sought short cuts to developing their higher education provision which has proved a lucrative income stream for some universities. But overseas collaborations are not without risk. Recipient countries can be concerned with external influence over curricula, quality being diluted and higher education being infected by neo-imperialism. These concerns are not without foundation. There are risks for providers too. Reputations can be damaged if academic standards are compromised. Conflicts of interest can occur between quality of provision and the pot of gold on offer. Staff can view overseas collaborations as distracting from their research and commitment to home students. Computing is a particularly popular subject for TNE, but critical thinking, analysis, independent learning, and creativity can be compromised. Preventing plagiarism is difficult. Constant changes in technology result in constant curricula revision which causes severe problems for overseas collaborations. This book focuses on TNE in the computing domain. However cross-cultural issues challenge TNE management and administration whatever the subject area. If the ever present tensions are not continuously monitored they can quickly threaten the sustainability of the collaboration. This book identifies many of the threats and some of the solutions. The readership for this book is truly global. Any international development officer in higher education considering an overseas collaboration will benefit from this book. Any academic becoming engaged in, or already involved with a TNE partnership, either as provider or recipient, will gain information and insight into the practice and issues. Researchers in TNE will discover more lines of enquiry. Students considering a course with an overseas provider or in coming to the UK to study will be better prepared thereby enabling a more fulfilling and rewarding experience. Anyone who has an interest in TNE, whether at the senior executive level, operational level, delivering programmes or as a recipient of TNE should read this book. The wealth of experience gathered here will provoke questions, prompt debate and offer solutions. It has been written by people who know the issues, bear the scars and are happy to share their knowledge. It will greatly benefit future transnational collaborations.
A Transnational History of the Internet in Central America, 1985–2000: Networks, Integration, and Development (Palgrave Macmillan Transnational History Series)
by Ignacio SilesThis Palgrave Pivot analyzes how six countries in Central America—Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama—connected to and through computer networks such as UUCP, BITNET and the Internet from the 80s to the year 2000. It argues that this story can only be told from a transnational perspective. To connect to computer networks, Central America built a regional integration project with great implications for its development. By revealing the beginnings of the Internet in this part of the world, this study broadens our understanding of the development of computer networks in the global south. It also demonstrates that transnational flows of knowledge, data, and technologies are a constitutive feature of the historical development of the Internet.
Transnational Research in Technical Communication: Stories, Realities, and Reflections (SUNY series, Studies in Technical Communication)
by Nancy Small; Bernadette LongoTransnational Research in Technical Communication considers the complexities of intercultural projects from a compelling perspective: first-hand narrative reflections. Readers go behind the scenes as scholars share their experiences crossing a variety of borders in their efforts to engage in knowledge-making endeavors. Interwoven through each chapter are stories of how projects were designed, adapted, and sometimes even failed. The collection begins with an introduction situating it at the intersection of recent scholarship in storywork, intercultural research, and technical and professional communication’s social justice turn. Each chapter concludes with discussion questions and recommendations for further reading. The closing chapter reveals a nascent "ethic of transnational and intercultural research" growing out of contributors' lessons learned and generous reflections. Anyone interested in or planning to undertake a transnational or intercultural project can benefit from these storied case studies, and as a result, this collection contributes to moving the field forward as it strives to promote more ethically aware and responsive research.
Transparency and Surveillance as Sociotechnical Accountability: A House of Mirrors (Routledge Studies in Science, Technology and Society #28)
by Deborah G. Johnson Priscilla M. ReganSurveillance and transparency are both significant and increasingly pervasive activities in neoliberal societies. Surveillance is taken up as a means to achieving security and efficiency; transparency is seen as a mechanism for ensuring compliance or promoting informed consumerism and informed citizenship. Indeed, transparency is often seen as the antidote to the threats and fears of surveillance. This book adopts a novel approach in examining surveillance practices and transparency practices together as parallel systems of accountability. It presents the house of mirrors as a new framework for understanding surveillance and transparency practices instrumented with information technology. The volume centers around five case studies: Campaign Finance Disclosure, Secure Flight, American Red Cross, Google, and Facebook. A series of themed chapters draw on the material and provide cross-case analysis. The volume ends with a chapter on policy implications.