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Toxicology of Nanoparticles: Insights from Drosophila
by Namita Agrawal Prasanna ShahThis book offers an unparalleled source of information on in vivo assessment of nanoparticle toxicity by using Drosophila as a model organism. Nanoparticles have emerged as an useful tool for wide variety of biomedical, cosmetics, and industrial applications. However, our understanding of nanomaterial-mediated toxicity under in vivo condition remains limited. The book begins with a chapter on synthesis and characterization of nanoparticles used for various biological, medical and commercial purposes. The rest of the chapters deal with the impact of nanoparticles on different biological aspects like behavior, physiology and metabolic homoeostasis using Drosophila as a model organism. Lastly, the book summarizes how proper characterization and evaluation of safe dosage of nanoparticles can be a boon if incorporated in consumer goods and for biomedical applications.Overall, the book pursues an interdisciplinary approach by connecting nanotechnology and biology from various angles using Drosophila as a model system, so as to develop more efficient, safe and effective use of nanoparticles for human beings.
Toxikologie für alle: Wann ist ein Stoff gefährlich?
by Helmut Greim Heidrun GreimWas man über Giftstoffe, deren Wirkung und Bewertung wissen muss: Zwei erfahrene Toxikologen erklären allgemeinverständlich, wann ein Stoff zum Schadstoff wird. Der Schwerpunkt liegt dabei auf den allgemeinen Grundlagen einer toxikologischen Untersuchung und Bewertung von Schadstoffen, sowie den daraus abgleiteten Handlungsempfehlungen. Anhand bekannter Beispiele aus den letzten Jahren, u. a. des Unkrautvernichters Glyphosat oder des Insektizids Fipronil, die beide in Nahrungsmitteln nachgewiesen wurden, wird erläutert, wie konkrete Gesundheitsgefährdungen anhand toxikologischer Daten und Verfahren ermittelt und welche Maßnahmen zum Schutz der Gesundheit daraus abgeleitet werden. Die Anwendung der toxikologischen Verfahren für die Bewertung von Gesundheitsrisiken wird anhand von Beispielen aus dem Alltag anschaulich dargestellt, von Lebensmitteln über Kosmetika bis hin zu Arzneimitteln und Alltagsprodukten. Ein kompakter, aber fundierter Einstieg in ein wichtiges und oft kontrovers diskutiertes Thema - für alle, die Toxine und deren Wirkungen auf Mensch und Umwelt verstehen wollen.
Toxikologie für Einsteiger
by Holger Barth Katharina Ernst Panagiotis PapatheodorouIn diesem kurzen Lehrbuch werden grundlegende wissenschaftliche und klinische Aspekte der Toxikologie dargestellt und ihre wichtigsten Inhalte, Ziele und Aufgaben beschrieben. Das Buch richtet sich an Studierende biowissenschaftlicher und chemischer Bachelor- und Masterstudiengänge, die Toxikologie als medizinisches Wahlfach belegen. Zu Beginn werden wichtige toxikologische Fachbegriffe definiert, um den Einstieg zu erleichtern. Es wird beschrieben was ein „Gift“ ausmacht und wie Giftstoffe in den menschlichen Körper gelangen können. Akute Vergiftungen, ihre Ursachen und die wichtigsten Maßnahmen für ihre Therapie werden im Einzelnen vorgestellt. Der Großteil des Lehrbuches beschreibt die Wirkung ausgewählter, medizinisch relevanter Giftstoffe aus Natur und Umwelt, häuslicher Umgebung und dem Arbeitsplatz wie Toxine aus Tieren, Pflanzen, Pilzen und Bakterien, Giftgase, Stäube, Metalle, Pestizide, Lösungsmittel und Alkohol. Am Ende werden die grundlegenden Prinzipien der chemischen Kanzerogenese zusammengefasst und die krebsauslösende Wirkung einiger toxikologisch wichtiger Substanzen exemplarisch vorgestellt sowie rechtliche Grundlagen im Umgang mit Giftstoffen zusammengefasst.
Toxins and Contaminants in Indian Food Products
by Ramesh Kumar Sharma Salvatore ParisiThis book discusses the complex of problems of contaminants in foods with the example of Indian food products. The presence and analytical detection of detrimental substances such as pesticides, mycotoxins and other biologically-produced toxins, food chemicals and additives with natural or industrial origin are treated. Furthermore, the book addresses the production and the commercial exploitation of native botanical ingredients, and the question if such ingredients should be regarded as foods or drugs. In the modern highly industrialized world, the interest in organic food production raises. The book sheds light on chemical aspects of organic farming practices in India. Readers will also find information on pesticides and other detrimental chemicals detection in Indian farming. In an outlook, the author reviews the resulting problems, such as how and why this can lead to border rejections during export, in particular to the European Union.
Toxins and Other Harmful Compounds in Foods (Chemical & Functional Properties of Food Components)
by A. Witczak Zdzislaw SikorskiToxins and Other Harmful Compounds in Foods provides information on the contents, distribution, chemical properties, and biological activity of toxins and other harmful compounds in foods that are natural components of the raw materials, accumulated due to microbial actions and environmental pollution, or are generated due to processing. This book shows how different factors related to the production of raw materials, as well as to storage and processing conditions, affect the presence and concentration of toxins and other harmful compounds in foods. It shows how various regulations, as well as unit operations and processes used in food production, may eliminate different toxins or generate new ones. The real health hazards for the consumers resulting from the presence of toxic/harmful compounds in aliments are discussed, and various national and international regulations obligatory in agriculture and industry aimed at increasing food safety are presented. Methods of analysis used for detection and determination of undesirable compounds are also discussed, making it possible to understand the effect of storage and processing parameters, as well as systems of quality assurance, on food safety and to select optimum procedures for analytical control.
Toxins in Food
by Waldemar M. Dąbrowski Zdzisław E. SikorskiWhile systems such as GMP and HACCP assure a high standard of food quality, foodborne poisonings still pose a serious hazard to the consumer's health. The lack of knowledge among some producers and consumers regarding the risks and benefits related to food makes it imperative to provide updated information in order to improve food safety.To
The Toyota Kaizen Continuum: A Practical Guide to Implementing Lean
by John StewartWritten by a recognized leader in the manufacturing industry with nearly two decades of experience working for Toyota, this book supplies a firsthand account of the realities behind implementing the Toyota Production System (TPS). The Toyota Kaizen Continuum: A Practical Guide to Implementing Lean presents authoritative insight on how to use the TPS to drive operational value and improvement across all segments of an organization.Highlighting valuable lessons learned directly from the TPS masters at the Toyota factories in Japan, John Stewart provides a time-tested approach for implementing a process of continuous improvement. Delving into his wide-ranging experience that includes time as a team member on the assembly line and managing the vehicle assembly division for Toyota`s largest European operation in the United Kingdom he explains how to get the process started, how to get senior management excited about the possibilities, and details a process for implementing the TPS in your organization. Written by an industry veteran named one of the Top 10 Automotive Executives by Automotive News in 2007 Unveils the methods used within the walls of the worlds premier manufacturing organization Illustrates valuable lessons learned with real-world examples of TPS implementations Describes five simple steps for executing change in any organization The book includes case studies that illustrate real-life successes and failures behind the walls of the worlds largest automobile manufacturing organization. Detailing a five-step process for executing improvement initiatives, it supplies you with the tools and understanding of the core principles of the TPS needed to implement and sustain a culture of continuous improvement in your organization.
Toyota Kaizen Methods: Six Steps to Improvement
by Isao Kato Art SmalleyToyota Kaizen Methods: Six Steps to Improvement focuses on the skills and techniques practiced inside Toyota Motor Corporation during the past decades. This workbook focuses on the actual training course concepts and methods used by Toyota to develop employee skill level, a core element of Toyota‘s success. It is not a book about holding Western-st
Toyota Methods and Operating Models: Achieve Business Success with the Toyota Way
by Stefano Cortiglioni Leonardo Salcerini Danilo VergaToyota Methods and Operating Models presents a case study of a small, traditional Italian manufacturer in the Toyota Industries Corporation Group, which began an important process of transformation until it became a successful, modern and advanced international business: Toyota Material Handling. Toyota management made internal changes and developed the commercial networks, successfully applying the Toyota Production System (TPS, or Lean Production) as well as the values of the Toyota Way. Author Stefano Cortiglioni led the transformation project, which took four years. Toyota Methods and Operating Models presents the continuing success story. The authors analyze the Toyota methods and operating models that can be directly applied to your business in order to reach excellence in operations and industry 4.0. It provides tangible advice on how to grow a business and achieve commercial success, with superior processes and logistics networks, as well as the development of an advanced and highly successful supply chain.
Toyota Production System: An Integrated Approach to Just-In-Time, 4th Edition
by Yasuhiro MondenA bestseller for almost three decades, Toyota Production System: An Integrated Approach to Just-In-Time supplies in-depth coverage of Toyota's production practices, including theoretical underpinnings and methods for implementation. Exploring the latest developments in the Toyota Production System (TPS) framework at Toyota, this new edition updates
The Toyota Way: 14 Management Principles from the World's Greatest Manufacturer
by Jeffrey K. LikerHow to speed up business processes, improve quality, and cut costs in any industry in factories around the world. Toyota consistently makes the highest-quality cars with the fewest defects of any competing manufacturer, while using fewer man-hours, less on-hand inventory, and half the floor space of its competitors. The Toyota Way is the first book for a general audience that explains the management principles and business philosophy behind Toyota's worldwide reputation for quality and reliability. Complete with profiles of organizations that have successfully adopted Toyota's principles, this book shows managers in every industry how to improve business processes by: Eliminating wasted time and resources, Building quality into workplace systems, Finding low-cost but reliable alternatives to expensive new technology, Producing in small quantities, and Turning every employee into a quality control inspector.
Toys!: Amazing Stories Behind Some Great Inventions
by Don WulffsonDescribes the creation of a variety of toys and games, from seesaws to Silly Putty and toy soldiers to Trivial Pursuit. <P><P>[This text is listed as an example that meets Common Core Standards in English language arts in grades 4-5 at http://www.corestandards.org.]
Toys and Sustainability (Environmental Footprints and Eco-design of Products and Processes)
by Subramanian Senthilkannan MuthuThis book presents five interesting chapters dealing with the sustainability of toys. The concept of sustainability has reached all industrial sectors these days and being practiced in almost all the sectors. One of the main sectors where sustainability has to be embedded to the core is the toy sector. Needless to enumerate the importance of sustainability in this sector especially when it comes to usage of chemicals and so on. There are various elements associated with the sustainability of toys and there is a dearth of published literature on this subject.
The TPM Playbook: A Step-by-Step Guideline for the Lean Practitioner (The\lean Playbook Ser.)
by Chris A. OrtizThis book is a guideline for implementation and it is intended for the Lean practitioner looking for a training tool and a guideline that can be used in the work area while improvements are being conducted. It describes how to effectively implement total productive maintenance.
TQM Engineering Handbook (Quality and Reliability)
by D.H. StamatisOffering a model, an implementing strategy, as well as traditional and nontraditional methods for the successful enhancement and maintenance of quality, this work establishes a rationale for the continuation of Total Quality Management (TQM) in all organizations. It considers leading quality-related topics, such as unusual charts, supplier-organiza
Trace-Based Post-Silicon Validation for VLSI Circuits
by Xiao Liu Qiang XuThis book first provides a comprehensive coverage of state-of-the-art validation solutions based on real-time signal tracing to guarantee the correctness of VLSI circuits. The authors discuss several key challenges in post-silicon validation and provide automated solutions that are systematic and cost-effective. A series of automatic tracing solutions and innovative design for debug (DfD) techniques are described, including techniques for trace signal selection for enhancing visibility of functional errors, a multiplexed signal tracing strategy for improving functional error detection, a tracing solution for debugging electrical errors, an interconnection fabric for increasing data bandwidth and supporting multi-core debug, an interconnection fabric design and optimization technique to increase transfer flexibility and a DfD design and associated tracing solution for improving debug efficiency and expanding tracing window. The solutions presented in this book improve the validation quality of VLSI circuits, and ultimately enable the design and fabrication of reliable electronic devices.
Trace Elemental Analysis of Metals: Methods and Techniques
by Thomas R. DulskiThis work details minor, trace and ultratrace methods; addresses the essential stages that precede measurement; and highlights the measurement systems most likey to be used by the pragmatic analyst. It features key material on inclusion and phase isolation. The book is designed to provide useful maps and signposts for metals analysts who must verify that stringent trace level compositional specifications have been met.
Trace Elements in Abiotic and Biotic Environments
by Alina Kabata-Pendias Barbara SztekeThis book helps readers understand the fundamental principles and phenomena that control the transfer of trace elements. It describes the occurrence and behavior of trace elements in rocks, soil, water, air, and plants, and also discusses the anthropogenic impact to the environment. In addition, the book covers the presence of trace elements in feeds, as either contaminants or as nutritional or zootechnical additives, and their transfer across the food chain to humans. All trace elements are covered-from aluminum to zirconium-as well as rare-earth elements (actinides and lanthanides).
Trace Elements in Coal and Coal Combustion Residues (Advances In Trace Substances Research Ser. #5)
by Robert F. Keefer Kenneth S. SajwanTrace Elements in Coal and Coal Combustion Residues focuses on trace metal chemistry of coal and coal combustion residues. Special emphasis is placed on management of coal combustion residues in electric power plants and the influence of coal and associated residues on soils, plants, water, and animals. Topics covered include a brief summary of research sponsored by Electric Power Research Institute, environmental pollution from coal combustion plants in low-rainfall regions, accumulation of trace elements in freshwater mussels near a power plant, testing to evaluate fossil fuel wastes by chemicals and isotopes, transport of metals from coal piles and ash impoundments, leachability and toxicity of metals in fly ash, and plant absorption of chemicals from ash. The book will be a useful reference for environmental and reclamation consultants, environmental engineers, toxicologists, environmental regulatory personnel, officials with electric power utilities and water treatment plants, and soil scientists.
Trace Elements in Soil: Bioavailability, Flux, and Transfer
by I. K. Iskandar M. B. KirkhamHistorically, research on the methods and amounts of trace element application to agriculture soils for correcting plant deficiencies has received major attention. More recently, due to industrial development and past disposal activities, trace elements are considered to be important environmental contaminants that affect all components in the atmo
Trace Elements in Soils and Plants
by Alina Kabata-PendiasStill the Gold Standard Resource on Trace Elements and Metals in SoilsThis highly anticipated fourth edition of the bestselling Trace Elements in Soils and Plants reflects the explosion of research during the past decade regarding the presence and actions of trace elements in the soil-plant environment. The book provides information on the biogeoch
Trace Elements in the Environment: Biogeochemistry, Biotechnology, and Bioremediation
by M.N.V. Prasad Kenneth S. Sajwan Ravi NaiduNew analytical techniques have enhanced current understanding of the behavior of trace and ultratrace elements in the biogeochemical cycling, chemical speciation, bioavailability, bioaccumulation, and as applied to the phytoremediation of contaminated soils. Addressing worldwide regulatory, scientific, and environmental issues, Trace Elements in th
Trace Elements in the Rhizosphere
by George R. Gobran Walter W. Wenzel Enzo LombiThe first book devoted to the complex interactions between trace elements, soils, plants, and microorganisms in the rhizosphere, Trace Elements in the Rhizosphere brings together the experimental, investigative, and modeling branches of rhizosphere research. Written by an international team of authors, it provides a comprehensive overview of the me
Trace Elements in Waterlogged Soils and Sediments (Advances in Trace Elements in the Environment #3)
by Anna Sophia Knox Michael PallerMany wetlands around the world act as sinks for pollutants, in particular for trace elements. In comparison to terrestrial environments, wetlands are still far less studied. A collaborative effort among world experts, this book brings the current knowledge concerning trace elements in temporary waterlogged soils and sediments together. It discusses factors controlling the dynamics and release kinetics of trace elements and their underlying biogeochemical processes. It also discusses current technologies for remediating sites contaminated with trace metals, and the role of bioavailability in risk assessment and regulatory decision making. This book is intended for professionals around the world in disciplines related to contaminant bioavailability in aquatic organisms, contaminant fate and transport, remediation technologies, and risk assessment of aquatic and wetland ecosystems.
Trace Environmental Quantitative Analysis: Including Student-Tested Experiments
by Paul R. LocontoA thorough and timely update, this new edition presents principles, techniques, and applications in this sub-discipline of analytical chemistry for quantifying traces of potentially toxic organic and inorganic chemical substances found in air, soil, fish, and water, as well as serum, plasma, urine, and other body fluids. The author addresses regulatory aspects, calibration, verification, and the statistical treatment of analytical data including instrument detection limits; quality assurance/quality control; sampling and sample preparation; and techniques that are used to quantify trace concentrations of organic and inorganic chemical substances. Key Features: Fundamental principles are introduced for the more significant experimental approaches to sample preparation Principles of instrumental analysis (determinative techniques) for trace organics and trace inorganics analysis An introduction to the statistical treatment of trace analytical data How to calculate instrument detection limits based on weighted least squares confidence band calibration statistics Includes an updated series of student-tested experiments