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Z-DNA: Methods and Protocols (Methods in Molecular Biology #2651)
by Kyeong Kyu Kim Vinod Kumar SubramaniThis detailed volume compiles key methods and techniques used to establish some of the structural and functional aspects of Z-form nucleic acids. Beginning with chapters on characterizing Z-DNA, the book continues by exploring structure determination techniques, gene- and genome-targeting methods and genome-wide approaches, Z-RNA study, and much more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Z-DNA: Methods and Protocols serves as an ideal guide for students and researchers curious about this unique Z nucleic acid as an area of investigation, aiming to help the field grow, flourish, and unravel the hidden and novel roles of Z. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.This is an open access book.
Zack Files 12: Now You See Me....Now You Don't
by Dan GreenburgA hypnotist's show turns out to be way more than Zack bargains for when he is pulled out of the audience, put into a trance, and his body is "taken over" by the spirit of someone from the past. And that's only the beginning, because the stubborn spirit won't go away when the show's over! It's hard enough having just one self to worry about. What will Zack do with two?
Zählverfahren und Lastannahme in der Betriebsfestigkeit
by Kurt Pötter Michael Köhler Sven Jenne Harald ZennerDie Betriebsfestigkeitsprüfung von Bauteilen ist u. a. erforderlich, um ihre Lebensdauer zu berechnen. Dazu werden verschiedene Methoden angewendet, die jeweils Vor- und Nachteile aufweisen. Bei schwingender Beanspruchung ist die Methode der Zählverfahren geeignet. Sie wird in dem vorliegenden Buch beschrieben und bewertet. Die Autoren bieten einen kompakten Überblick über den Stand der Technik und liefern Empfehlungen für die Anwendung in der Praxis.
Zap!
by Martha FreemanEleven-year-old Luis is left looking for answers after a city-wide blackout leads him to an electrifying mystery in this edge-of-your-seat thriller from Martha Freeman.Luis Cardenal is toasting a Pop-Tart when a power outage strikes Hampton, New Jersey. Elevators and gas pumps fail right away; soon cell phones die and grocery shelves empty. Cold and in the dark, people begin to get desperate. Luis likes to know how things work, and the blackout gets him wondering: Where does the city’s electricity come from? What would cause it to shut down? No one seems to have answers, and rumors are flying. Then a slip of the tongue gives Luis and his ex best friend Maura a clue. Brushed off by the busy police, the two sixth graders determine they are on their own. To get to the bottom of the mystery, they know they need to brave the abandoned houses of Luis’s poor neighborhood and find the homeless teen legend known as Computer Genius. What they don’t know is that someone suspects they know too much, someone who wants to keep Hampton in the dark. In this electrifying mystery, two can-do sleuths embark on a high-tech urban adventure to answer an age-old question: Who turned out the lights?
Zap! It's Electricity! (My Science Library)
by Buffy SilvermanIntermediate Readers Explore Electricity.
Zebrafish: A Practical Guide to Husbandry, Welfare and Research Methodology
by Rita Almeida Kamar E. Ameen-Ali James Bull Carolina Cabrera Joanna Cambray-Young Ana Catarina Certal Karishma Chhabria Pam S. Ellis Catarina M. Henriques Sara Hilditch Michael L. Kent Peter Laud Christian Lawrence Raquel R. Martins Sandra Martins Mollie E. Millington Joana Monteiro Katrina N. Murray Paul G. Schroeder Lynne U. Sneddon Amy Spencer Eleanor StillmanAfter securing popularity in home aquariums, zebrafish have also become an essential animal for biomedical research. Ensuring they are adequately cared for in research settings is therefore of the utmost importance and this book is designed to help laboratories develop good welfare and husbandry practices, refine procedural protocols and engage with ethical obligations. A wide range of topics are addressed, starting with husbandry aspects such as environmental enrichment, nutrition, housing conditions, diseases, health monitoring, biosecurity and larval rearing. More experimental topics are then discussed, such as genotyping, ageing, imaging, behavioural studies, experimental design and statistics. Ethical challenges are also considered through the environmental impact of aquatic facilities and the 3Rs - Replacement, Reduction and Refinement - with a focus on anaesthesia, analgesia, euthanasia and severity assessment. Zebrafish are a shoaling species by nature but this book also takes into account their individual needs by providing: - practical advice from experienced zebrafish caretakers; - bridges between data acquisition and fish welfare; and - the latest guidance for reporting, reproducibility and compliance. This book is written for zebrafish facility personnel and for researchers who are aware of the need for robust care for their zebrafish model. It also provides an unparalleled insight for ethics committee members with the intention to provide the best care possible for this ever-important fish.
Zeitmanagement für Ingenieure (essentials)
by Ekbert HeringIngenieure in Führungsverantwortung sind in besonderer Weise Stress und Hektik ausgesetzt. Ein effektives und effizientes Zeitmanagement hilft dabei, die erforderlichen Ziele zu erreichen und ist ein wichtiger Schlüssel zu mehr Lebensqualität. Nach einer persönlichen Selbsteinschätzung werden die biologischen Gegebenheiten vorgestellt, wie die Leistungs-, Stör- und Konzentrationskurven. Zur Auswahl von Entscheidungen werden die Aufgaben je nach Dringlichkeit und Wichtigkeit in das Eisenhower-Portfolio eingetragen. Daraus lassen sich Prioritäten bestimmen. Als universell einsetzbare Methode für das Zeitmanagement wird die ALPEN-Methode ausführlich behandelt (A: Aktivitäten zusammenstellen; L: Länge der Aktivitäten abschätzen; P: Pufferzeiten reservieren: E: Entscheidungen fällen; N: Nachkontrolle). Wertvolle Tipps werden gegeben zum rationellen Arbeiten in Zeitblöcken, zum Besprechungs-, Telefon- und Besucher-Management sowie zum Umgang mit Zeiträubern und zum Zeitsparen. Zum Schluss wird gezeigt, dass das Zeitmanagement nur in der work-life-balance seinen sinnvollen Platz hat.
Zeke Bartholomew: Superspy!
by Jason PinterZeke Bartholomew has always dreamed of being a spy. But when a case of mistaken identity goes horribly wrong, he's thrust into a world of real-life espionage beyond his wildest dreams. Soon this 7th grade nobody finds himself hunted by the lava-powered behemoth Ragnarok, aided by a mysterious butt-kicking girl who goes only by the codename 'Sparrow', while trying to stop the evil mastermind Le Carré from unleashing a device that will turn millions of kids around the world into brainwashed zombie minions. Zeke has always been a zero, and unless he can fumble his way towards becoming a hero, the world is doomed...Full of action, humor, suspense, and more impractical spy gadgets than you can imagine, Zeke Bartholomew is a hero for a new generation. The fate of the world is in his hands! (uh oh...)
Zelda's Big Adventure
by Marie Alafaci Shane McGZelda has big plans—she wants to be the first chicken in space. She leaves nothing to chance as she builds her spaceship, plans her experiments, and packs for the journey. All she needs now is a little help from her friends, and if they won’t step up, Zelda will just have to manage on her own! Eye-popping art and a story of perseverance and ingenuity prove that for a plucky hen, the sky is never the limit.This modern twist on the traditional The Little Red Hen story features an endearing and resourceful chicken determined to fulfill her dream.
ZEMCH: Toward the Delivery of Zero Energy Mass Custom Homes
by Masa NoguchiIn this book, leading international experts explore the emerging concept of the zero energy mass custom home (ZEMCH) - designed to meet the need for social, economic, and environmental sustainability - and provide all of the knowledge required for the delivery of zero energy mass customized housing and community developments in developed and developing countries. The coverage is wide ranging, progressing from explanation of the meaning of sustainable development to discussion of challenges and trends in mass housing, the advantages and disadvantages of prefabricated methods of construction, and the concepts of mass customization, mass personalization, and inclusive design. A chapter on energy use will aid the reader in designing and retrofitting housing to reduce energy demand and/or improve energy end‐use efficiency. Passive design strategies and active technologies (especially solar) are thoroughly reviewed. Application of the ZEMCH construction criteria to new buildings and refurbishment of old houses is explained and the methods and value of building performance simulation, analyzed. The concluding chapter presents examples of ZEMCH projects from around the world, with discussion of marketing strategy, design, quality assurance, and delivery challenges. The book will be invaluable as a training/teaching tool for both students and industry partners.
Zendegi
by Greg EganNasim is a young computer scientist, hoping to work on the Human Connectome Project: a plan to map every neural connection in the human brain. But funding for the project is cancelled, and Nasim ends up devoting her career to Zendegi, a computerised virtual world used by millions of people.Fifteen years later, a revived Connectome Project has published a map of the brain. Zendegi is facing fierce competition from its rivals, and Nasim decides to exploit the map to fill the virtual world with better Proxies: the bit-players that bring its crowd scenes to life. As controversy rages over the nature and rights of the Proxies, a friend with terminal cancer begs Nasim to make a Proxy of him, so some part of him will survive to help raise his orphaned son. But Zendegi is about to become a battlefield ...
Zendegi
by Greg EganNasim is a young computer scientist, hoping to work on the Human Connectome Project: a plan to map every neural connection in the human brain. But funding for the project is cancelled, and Nasim ends up devoting her career to Zendegi, a computerised virtual world used by millions of people.Fifteen years later, a revived Connectome Project has published a map of the brain. Zendegi is facing fierce competition from its rivals, and Nasim decides to exploit the map to fill the virtual world with better Proxies: the bit-players that bring its crowd scenes to life. As controversy rages over the nature and rights of the Proxies, a friend with terminal cancer begs Nasim to make a Proxy of him, so some part of him will survive to help raise his orphaned son. But Zendegi is about to become a battlefield ...
The Zenith Angle: A Novel
by Bruce Sterling&“Gleeful, shrewd, speculative, cynical, closely observed . . . The Zenith Angle offers wisdom and solace, thrills and laughter.&”—The Washington Post&“Compelling and important . . . A darkly comic fable of info-war, the black budget, über-geek idealism, and the politics of Homeland Insecurity.&”—William Gibson, author of Pattern Recognition Pioneering computer wizard Derek &“Van&” Vandeveer has been living extra-large as a VP for a booming Internet company. But the September 11 attacks on America change everything. Recruited as the key member of an elite federal computer-security team, Van enters the labyrinthine trenches of the Washington intelligence community. His special genius is needed to debug the software glitch in America&’s most crucial KH-13 satellite, capable of detecting terrorist hotbeds worldwide. But the problem is much deeper. Now Van must make the unlikely leap from scientist to spy, team up with a ruthlessly resourceful ex-Special Forces commando, and root out an unknown enemy—one with access to a weapon of untold destructive power.&“Great fun . . . A cyberthriller of 21st-century technologies [that] peeps wittily behind the national security scenes of a modern superpower.&”—New Scientist&“A comedic thriller for the homeland security era.&”—Entertainment Weekly
Zenn Scarlett
by Christian SchoonZenn Scarlett is a bright, determined, occasionally a-little-too-smart-for-her-own-good 17-year-old girl training hard to become an exoveterinarian. That means she's specializing in the treatment of exotic alien life forms, mostly large and generally dangerous. Her novice year of training at the Ciscan Cloister Exovet Clinic on Mars will find her working with alien patients from whalehounds the size of a hay barn to a baby Kiran Sunkiller, a colossal floating creature that will grow up to carry a whole sky-city on its back.But after a series of inexplicable animal escapes from the school and other near-disasters, the Cloister is in real danger of being shut down by a group of alien-hating officials. If that happens, Zenn knows only too well the grim fate awaiting the creatures she loves.Now, she must unravel the baffling events plaguing her school, before someone is hurt or killed, before everything she cares about is ripped away from her and her family forever. To solve this mystery - and live to tell about it - Zenn will have to put her new exovet skills to work in ways she never imagined, and in the process learn just how powerful compassion and empathy can be.
Zenn Scarlett
by Christian SchoonZenn Scarlett is a bright, determined, occasionally a-little-too-smart-for-her-own-good 17-year-old girl training hard to become an exoveterinarian. That means she's specializing in the treatment of exotic alien life forms, mostly large and generally dangerous. Her novice year of training at the Ciscan Cloister Exovet Clinic on Mars will find her working with alien patients from whalehounds the size of a hay barn to a baby Kiran Sunkiller, a colossal floating creature that will grow up to carry a whole sky-city on its back.But after a series of inexplicable animal escapes from the school and other near-disasters, the Cloister is in real danger of being shut down by a group of alien-hating officials. If that happens, Zenn knows only too well the grim fate awaiting the creatures she loves.Now, she must unravel the baffling events plaguing her school, before someone is hurt or killed, before everything she cares about is ripped away from her and her family forever. To solve this mystery - and live to tell about it - Zenn will have to put her new exovet skills to work in ways she never imagined, and in the process learn just how powerful compassion and empathy can be.
Zentralstaubsauger für Einfamilienhäuser und Wohnungen: Eine kurze Einführung in Aufbau und Funktion (essentials)
by Marcus DunstDer Zentralstaubsauger sorgt für einen sauberen Wohnraum, ohne die Luftqualität zu beeinträchtigen. Das Rohrsystem wird während der Bauphase mit integriert. Deshalb muss der Zentralstaubsauger bei der Planung im Rohbau berücksichtigt werden. Für einen Allergiker ist der Zentralstaubsauger die beste Variante, um sich vom „Hausstaub“ zu befreien. Bei allen anderen Personen sorgt der Zentralstaubsauger im Alltag für mehr Hygiene und Wohnkomfort, egal ob in den Privaträumen oder Büro. Die Technik hat sich schon lange bewährt und wird in Europa seit über 30 Jahren genutzt. Doch viele kennen das Produkt nicht.
Zeolite Characterization and Catalysis
by E. G. Derouane Arthur W. ChesterZeolites have been an important material in catalysis and other applications (adsorbents, detergents) for the last 50 years. While new types of porous materials (ordered mesopores, metal organic frameworks) are now attracting more R&D attention, zeolites are still the most important crystalline industrial catalysts. Zeolite Characterization and Catalysis: A Tutorial makes available a series of tutorials on zeolite characterization and catalysis. Topics covered include X-ray powder diffraction, infra-red and Raman spectroscopy, Electron microscopy, determination of acid/base properties, the important reactions of C1 building blocks over zeolites as well as zeolite catalysis in chemicals . An important chapter covers computational methods in zeolite science. Zeolite Characterization and Catalysis: A Tutorial is intended for graduate students, post-docs and experienced scientists entering the fields of synthesis, characterization and catalytic applications of porous materials.
Zero – Much to Do About Nothing?
by Jim E. RiviereZero – Much to Do About Nothing? is a thought-provoking work that delves into the complexities of defining “zero” in various fields, from mathematics and physics to pharmacology and food safety. Drawing on his extensive experience in teaching, research and managing a USDA-supported chemical food safety program, Jim E. Riviere provides readers with practical examples and case studies that highlight the challenges of defining “zero” in different contexts across a wide range of fields. In his four decades of university teaching, doing research in pharmacology, toxicology, biomathematics and nanoscience, Dr. Riviere has repeatedly encountered the concept of “zero” and the broad parameters utilized to achieve a proper definition. "Zero” enters when discussions concern defining "nothing", "negligible", "very small", "below level of detection", "absence of effect" or "safe". This renders the term “zero” incredibly confusing to scientists, practitioners and regulators. This book explores the origin of the concept of “zero” in mathematics, physics, chemistry and statistics and how these concepts migrated to fields such as pharmacology, toxicology, cancer research and food safety, as well as to the legal profession in the form of regulatory science and policy. Specific chapters deal with the application of “zero” to these distinct fields. The main focus throughout the book is to illustrate how important context is to the definition of “zero”. This has assumed greater relevance today with the advent of nanoscience where “small” implies different physical and chemical behavior and the use of artificial Intelligence to analyze vast troves of data from the web. The goal of the book is to provide much-needed clarity about "zero" and break down the many issues preventing it. Riviere expertly explains how the concept of “zero” is essential to a wide range of issues, from defining negligible amounts of a substance to determining the safety of a product or process. He shows how the term “zero” can have different meanings in different fields and how this can lead to confusion and misunderstandings among scientists, practitioners and regulators. Whether you're working in Food Safety, Chemistry, Pharmacology, Mathematics, Physics or beyond, Zero – Much to Do About Nothing? is a relatable book that will deepen your understanding of the concept of “zero” and its diverse applications.
Zero Bomb
by M.T HillFrom Philip K. Dick Award-nominated author M.T. Hill, Zero Bomb is a startling science fiction mystery that asks: what do we do when technology replaces our need to work?The near future. Following the death of his daughter Martha, Remi flees the north of England for London. Here he tries to rebuild his life as a cycle courier, delivering subversive documents under the nose of an all-seeing state.But when a driverless car attempts to run him over, Remi soon discovers that his old life will not let him move on so easily. Someone is leaving coded messages for Remi across the city, and they seem to suggest that Martha is not dead at all.Unsure what to believe, and increasingly unable to trust his memory, Remi is slowly drawn into the web of a dangerous radical whose '70s sci-fi novel is now a manifesto for direct action against automation, technology, and England itself.The deal? Remi can see Martha again - if he joins the cause.
Zero-Carbon Energy Kyoto 2012
by Takeshi YaoThe Global COE is setting out a zero-emission technology roadmap and is promoting socioeconomic studies of energy, studies of new technologies for renewable energies, and research for advanced nuclear energy. It has also established the Global COE Unit for Energy Science Education to support young researchers as they apply their skills and knowledge and a broad international perspective to respond to issues of energy and the environment in our societies. This book follows on the earlier volumes Zero-Carbon Energy Kyoto 2009, 2010, and 2011.
Zero Carbon Industry, Eco-Innovation and Environmental Sustainability (World Sustainability Series)
by Rubee Singh Amit Joshi Walter Leal Filho Shahbaz KhanThis book provides the latest research on zero carbon industry and its practical implications for eco-innovation and environmental sustainability for businesses in current scenario. In a zero-carbon industry, there would be profound, sometimes disruptive, changes in our economy compared to our current one. As the world approaches zero carbon industry by 2050, economic output will shift progressively (and permanently) toward those goods and services that do not emit greenhouse gases. Changes in these dynamics would ripple along entire value chains, transforming industries. Creating a zero-carbon industry will require fundamental changes in both our economies and societies. Taking eco-innovation and environmental sustainability seriously will be crucial to businesses, and companies are increasingly keen to signal this commitment. This book aims to illustrate a detailed exploration of the complex and interconnected domains of zero carbon industry, eco-innovation, and environmental sustainability. In addition to combining the academic expertise of emerging and established scholars from different academic fields, this book provides an integrated understanding of the topic on zero carbon emissions, eco-innovation, and environmental sustainability from a broader perspective by combining the work of established and emerging scholars. There is a need to fundamentally transform the zero carbon industry, eco-innovation ecosystem in order to achieve sustainability through the implementation of Industry 4.0 technologies such as artificial intelligence, Internet of things, blockchain, and cloud technologies. The book sheds light on various advancements in zero carbon industry, eco-innovation, and emerging technologies for the purpose of sustainability, and it aims to address the urgency of responding to the UN Sustainable Development Goals (UN-SDGs) as part of the global mandate.
Zero Emissions Power Cycles
by Evgeny Yantovsky J. Gorski Mykola ShokotovFocusing on fossil-fueled, nonpolluting power generation systems, Zero Emissions Power Cycles presents alternative solutions to the severe emissions problems of power plants. Along with a description of new thermodynamic cycles and the results of computational analyses, this volume provides modern analytical tools and equations to evaluate exergy a
Zero Footprint: The true story of a private military contractor's secret wars in the world's most dangerous places
by Simon ChaseSimon Chase's life is a maze of burner phones, encrypted emails, secret meetings, and weaponry - all devoted to executing missions too sensitive for government acknowledgement. Working for shadowy British and American organisations, Chase has been on the trail of Bin Laden in Afghanistan, protected allied generals in Iraq, and been part of an operation directly related to the attack in 2012 on the US consulate in Benghazi.Zero Footprint takes us to this dangerous and thrilling world, and tells the true story of a private military contractor whose work forms the foundation for western security abroad, especially when the UK and US military, intelligence agencies, and departments of state need something done that they can't - or won't - do themselves.
Zero-G (Outer Earth #2)
by Rob BoffardZERO-G is the nonstop sequel to Rob Boffard's Tracer, a brutal, gripping thrill-ride, where the hero moves like lightning and the consequences for failure are deadly.The clock is ticking down again for Riley Hale. She may be the newest member of Outer Earth's law enforcement team, but she feels less in control than ever. A twisted doctor bent on revenge is blackmailing her with a deadly threat. If Riley's to survive, she must follow his orders, and break a dangerous prisoner out of jail. To save her own skin, Riley must go against all her beliefs, and break every law that she's just sworn to protect. Riley's mission will get even tougher when all sectors are thrown into lock-down. A lethal virus has begun to spread through Outer Earth, and it seems little can stop it. If Riley doesn't live long enough to help to find a cure, then the last members of the human race will perish along with her. The future of humanity hangs in the balance. And time is running out.
The Zero-G Headache (AstroKids #2)
by Robert ElmerMeet the AstroKids--DeeBee, Buzz, Miko, Mir, and Tag--five friends learning biblical truth through out-of-this-world adventures aboard space station CLEO-7. "'DeeBee's a GEEN-ius.' Suffering satellites, that's all I ever hear! So I understand basic quantum theory. I mean, who doesn't, right? "Anyway, can you believe it? Zero-G, The most popular band in the galaxy, was coming to perform at CLEO-7. Now. . . I think Zero-G's music is pretty lame -- but don't tell that to the other AstroKids! I was more interested in finding out why my geeky cousin Phil was on Zero-G's shuttle. . . and what exactly he was hiding in that mysterious blue plasma barrel".