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Co-simulations of Microwave Circuits and High-Frequency Electromagnetic Fields
by Mei Song Tong Xiao Yu LiThis book aims to provide many advanced application topics for microwave circuits and high-frequency electromagnetic (EM) fields by using advanced design system (ADS) and high-frequency structure simulator (HFSS) as simulation platforms. In particular, it contains the latest multidisciplinary co-simulation guidance on the design of relevant components and devices. Currently, the circuit/field design and performance analysis and optimization strongly rely on various kinds of robust electronic design automation (EDA) software. RF/microwave engineers must grasp two or more types of related simulation design software. ADS by Keysight and HFSS by Ansys are the representative for circuit simulations and for field and structural simulations of microwave devices, respectively. At present, these two types of software are widely used in enterprises, universities, and research institutions. The main purpose of this book is to enable readers, who are interested in microwave engineering and applied electromagnetics, to master the applications of these two tools. It also helps readers expand their knowledge boundaries behind those types of software and deepen their understanding of developing interdisciplinary technologies by co-simulations. The book is divided into three parts. The first part introduces the two latest versions of ADS and HFSS and helps readers better understand the basic principles and latest functions better. It also advises how to choose appropriate simulation tools for different problems. The second part mainly describes co-simulations for high-frequency EM fields, microwave circuits, antenna designs, EM compatibility (EMC), and thermal and structural analyses. It provides guides and advices on performing co-simulations by ADS and HFSS incorporated with other types of software, respectively. The last part narrates the automation interfaces and script programming methods for co-simulations. It primarily deals with the Advanced Extension Language (AEL), Python Data Link (PDL), and MATLAB interface in ADS. For HFSS, it discusses VBScript, IronPython scripting, and Application Programming Interface (APIs) based on MATLAB. Each topic contains practical examples to help readers understand so that they can gain a solid knowledge and skills regarding automated interfaces and scripting methods based on these kinds of software. Concisely written in combination with practical examples, this book is very suitable as a textbook in introductory courses on microwave circuit and EM simulations and also as a supplementary textbook in many courses on electronics, microwave engineering, communication engineering, and related fields. As well, it can serve as a reference book for microwave engineers and researchers.
Principles and Practice of Neurocritical Care
by Hemanshu Prabhakar Vasudha Singhal Kapil G Zirpe Harsh SapraThis official textbook of the Society of Neurocritical Care (SNCC) comprises a comprehensive review of all possible neurologic conditions that one may encounter in the practice of neuro-intensive care. It covers various topics, from the history and origin of neuro-intensive care to psychological and nursing care. Neurocritical care is the intensive care management of patients with life-threatening neurological and neurosurgical illnesses such as massive stroke, bleeding in or around the brain (subarachnoid hemorrhage, intracerebral hemorrhage, subdural hemorrhage, intraventricular hemorrhage), brain tumors, brain trauma, status epilepticus, nerve and muscle diseases (myasthenia gravis, Guillain-Barre Syndrome), spinal cord disorders and the cardiopulmonary complications of brain injury. Neurocritical care units specialize in managing the unique needs of such critically ill patients. The textbook is divided into many sections. Chapters discuss issues related to palliative care and describe some of the commonly performed procedures in the neuro-intensive care unit as well. It provides a straightforward and systematic approach to various clinical problems encountered during intensive care management of neurologic patients. It includes a separate section on special considerations in neurocritical care. The book includes ample figures, flowcharts and algorithms. The textbook is a valuable resource for residents, fellows and trainees in neuroanesthesia, neurointensive care, critical care, and anesthesia. It serves as a quick guide to all intensivists managing neurosurgical patients. It is also helpful for general intensivists who occasionally manages neurologic patients.
Proceedings of the 8th International Conference on Sustainable Urban Development: ICSUD 2022, Binh Duong - Ho Chi Minh City, Vietnam (Advances in 21st Century Human Settlements)
by Hans-Joachim Linke Vien Thuc Ha Hieu Ngoc NguyenThis book includes peer-reviewed articles from the 8th International Conference on Sustainable Urban Development (ICSUD 2022), held at the Vietnamese-German University (VGU) in Vietnam. The theme of the conference is “innovative and inclusive growth models for sustainable urban development”. Articles in this book present major issues that cities and regions around the world are facing these days to adapt to new, unexpected, and profound challenges.Over past few years, the world has been observing meaningful reactions to crises. From the pandemic to war, energy, and food shortages, there are always opportunities for innovations. Some firms still thrived in the city lock-down; some groups stayed healthier with less income; and certain municipalities consumed less resources to attain higher outcomes. However, the rise of digital economy, the importance of proximity or near-shore supply chain, or the new contribution of different communities at different levels are generalized asnew growth models for changes.
Seismic Performance of Corroded Reinforced Concrete Structures Retrofitted with FRP
by Dejian ShenThis monograph is written based on the author's research on seismic assessment and retrofitting of corrosion-damaged reinforced concrete structures during the recent two decades. It points out that reinforcement corrosion is one of the main reasons that contribute to the deterioration of the seismic performances and durability of reinforced concrete structures. It illustrates that the mechanism of reinforcement corrosion should be investigated to propose a method for evaluating the seismic performance of corroded components and structures. It calls for a comprehensive investigation on the bond performance between corroded reinforcing bars and concrete, as well as the degradation law of seismic performance of corroded beams, columns, beam column joints, and shear walls from the perspectives of materials, components, and structures. With the promotion and application of composite materials, fiber reinforced polymer (FRP) has been proposed as an ideal material for retrofitting reinforced concrete structures. By emphasizing the mechanism of reinforcement corrosion and the integrated evaluation of materials, components, and structures, this monograph offers an idea of using FRP to retrofit the seismic performance of corroded reinforced concrete structures. It is designed as a reference work for professionals or practitioners and a textbook for undergraduates or postgraduates. This book provides valuable knowledge and useful methods that can be considered in the field of seismic assessment and retrofitting of corrosion-damaged reinforced concrete structures with other FRPs.
A Guide to Hormonal Dermatology
by Nidhi Sharma Ramanjit SinghThis book covers all aspects of how various Hormonal diseases affect Skin Health. It covers essential parts of the most common Hormonal disease - Polycystic Ovarian Disease (PCOD), i.e., its Pathogenesis, investigations, and individual clinical features with their Line of management.Chapters also provide information about other common yet less discussed hormonal issues like- Diabetes, Thyroid disease, and obesity affecting the skin and what signs and symptoms should be looked for in such patients for early diagnosis and treatment.Hence, this book assists Dermatologists, Consulting Physicians, Post Graduates, and Interns in a holistic understanding and practical management of standards as well as other miscellaneous issues like Diet and Hormones and Urticaria and Hormones.
Regional Development and Its Spatial Structure
by Dadao LuThis book describes the progress and prominent theories of regional development research in the past decades, especially in the past decade, discusses the industrial structure, spatial structure, resources, and environment, as well as a series of practical issues, and reveals the general characteristics of spatial structure evolution in the process of regional development. The research on the issues of regional development has become the frontier of relevant disciplines since the 1950s, and much progress has been made in the process of solving practical problems in social and economic development. This book provides an in-depth and systematic demonstration of the "point-axis system" theory of regional exploitation and development as well as the T-shaped structure of China's regional economic action in theory and practice and discusses the impact of location differential rent, restricted accessibility, technological innovation, etc., on regional development theoretically. This book is used as a reference for planning, scientific research, and teaching personnel in territorial expansion, regional economy, human geography, etc.
Anwendungen des Cuckoo-Suchalgorithmus und seiner Varianten
by Nilanjan DeyDieses Buch betont die grundlegenden Konzepte des CS-Algorithmus und seiner Varianten sowie deren Anwendung zur Lösung unterschiedlicher Optimierungsprobleme in medizinischen und ingenieurwissenschaftlichen Anwendungen. Evolutionäre metaheuristische Ansätze werden zunehmend zur Lösung komplexer Optimierungsprobleme in verschiedenen realen Anwendungen eingesetzt. Einer der erfolgreichsten Optimierungsalgorithmen ist die Cuckoo-Suche (CS), die zu einem aktiven Forschungsbereich geworden ist, um N-dimensionale und lineare/nichtlineare Optimierungsprobleme mithilfe einfacher mathematischer Prozesse zu lösen. CS hat die Aufmerksamkeit verschiedener Forscher auf sich gezogen, was zur Entstehung zahlreicher Varianten des grundlegenden CS mit verbesserten Leistungsmerkmalen seit 2019 geführt hat.
Studies in Silk Road Archaeology
by Nai XiaThis book is a collection of Nai Xia’s quintessential works on Silk Road studies. A key resource in the field of Silk Road Archaeology, it features in-depth content, a broad range of material, careful textual research, and meticulous analysis. With thorough investigations of foreign coinage, silk textiles, and artifacts with foreign styles excavated in different parts of China, it explores the exchange between ancient China and Central Asia, Western Asia, and Europe. In particular, this book provides detailed descriptions of the economic and cultural ties between ancient China, Pre-Islamic Arabia, the Sasanian Empire, and the Byzantine Empire. The research propounds innovative theories on the history and evolution of East-West transportation routes, i.e., the overland Silk Road and the Maritime Silk Road. Based on the study of ancient relics and excavated artifacts, it points out that cultural exchange along the Silk Road was never unilateral, but instead, mutual influence and cooperation were obvious. Since ancient times, countries along the Silk Road have had a tradition of amicable foreign relations and the promotion of common interests. The book is intended for academics, scholars and researchers.
Education in the Post-COVID-19 Era—Opportunities and Challenges: Proceeding of 2022 International Conference on Learning and Teaching in the Digital World (Lecture Notes in Educational Technology)
by Ahmed Tlili Saida Affouneh Soheil Salha Sameer Abu-EishehThis book offers authors’ practices, initiatives, and experiences in sustaining their education during the pandemic from different countries, contexts, and political situations. It provides a future prediction for the education system in the world due to the transformation that happened in the post-COVID-19 era. Each chapter of the book is expected to shed light on different countries describing their education system in the past, present, and future. The readers of the book will be able to learn, compare, and analyze the differences and similarities between the educations offered to learners around the world.The book also presents a new model of e-learning that will help learners, teachers, and educational systems to participate in achieving sustainable development goals. The book introduces several scenarios of types of learning and how to plan, design, and implement them in F2F and online environments.
Neuroprotective Effects of Phytochemicals in Brain Ageing
by Surajit Pathak Antara BanerjeeThis book discusses the mechanism and therapeutic strategies of phytochemicals against brain ageing. It discusses the underlying anti-oxidative and anti-inflammatory mechanisms of the phytochemicals and the implications of these compounds in the prevention and treatment of geriatric diseases. It discusses the potential role of the highly complex interactive network between the gut and the brain in neurodegenerative diseases such as Parkinson’s disease (PD), and Alzheimer’s disease. The chapters provide insight into the mechanisms involved in brain ageing and the mechanism of actions of the phytochemicals that might be crucial in developing effective new therapies against brain ageing. The chapter also presents the mechanisms of action of phytoconstituents, bioavailabilities, and their effects on neuroinflammation. The chapters also examine the phytochemicals protection of neurons via targeting oxidative stress, mitochondrial dysfunction, neurotrophic factor deficit, apoptosis, and abnormal protein accumulation. This book aims to provide comprehensive and cutting-edge information on the potential neuroprotective role of phytochemicals on the brain and neurological disorders to researchers, neuroscientists, clinical nutritionists, and physicians.
Ear Diseases and CT
by Zilong YuThis book consisted of 12 chapters, 280 color figures and 200 white & black figures; each figure was followed by a detail annotation.In the first part, the anatomy and surgical mark of the following structures were described respectively in detail: five portions of the temporal bone, external-media-internal ear, facial nerve in temporal bone, cerebellopontine angle and petrous apex. This is the basics of understanding the anatomic marks of normal radiological imaging and pathological-radiological imaging.In the second part, two-dimension CT imaging of temporal bone and the corresponding sectional anatomy of the same temporal bone were compared one by one on axial, coronal and sagittal view. Surgical and radiologic anatomic structures were marked in each section, their clinical significances were also explained in the meantime.In the third part, it covers 10 kinds of ear diseases using CT imaging in each part. It includes congenital malformation, trauma, inflammation, cholesteatoma. tumor and neighbor disease which affected the temporal bone, were described in detail respectively, some diseases attached MRI imaging and surgical findings. This may help for understanding radiological imaging and planning preoperative design.This book is useful for Otolaryngology & Head and Neck Surgery, Radiology doctors and related teaching personals.
Thyroid FNA Cytology: Differential Diagnoses and Pitfalls
by Kennichi Kakudo Zhiyan Liu Chan Kwon Jung Mitsuyoshi Hirokawa Andrey Bychkov Chiung-Ru LaiThis is the third edition of a well-received book that recapitulates the thyroid fine-needle aspiration (FNA) cytology. It covers the basics and critical principles of thyroid cytopathology, addresses technical aspects, and presents the latest breakthrough events in the field, including the new editions of the WHO classification of thyroid tumors and the Bethesda system for reporting thyroid cytopathology.Thyroid FNA Cytology, The Third Edition is a practical handbook for cytopathologists, pathologists, cytotechnologists, endocrinologists, thyroid surgeons, radiologists, thyroid cancer patients, and their families. This edition covers more topics than the previous editions and invites authors from 20 countries from Asia, Europe, and America. It should serve as an individualized guide to readers practicing in various geographic areas with different medical settings and social resources. The book provides multiple chapters on differential diagnosis and pitfalls to show the unique approaches in many countries. The book will broaden their perspectives and serve as a foundation for further advancement in this field.
Handbook of Biomass
by Sabu Thomas Cintil Jose Chirayil Mahesh Hosur Daniel PasquiniThis handbook constitutes state-of-the-art research covering topics such as chemical constituents of biomass, their specific properties, characterization and different applications. The contents also discuss challenges and issues involved in its applications. This volume brings together a number of biomass-derived potential renewable elements and its circular economy approach in one place. The content includes industrial applications and fills the gap in laboratory research works to practical applications in related industries. The book gives an insight towards the circular economy approach by the biomass, different gross morphologies of biomasses and the valuable chemical constituents that can be derived from the biomass and moreover the potential applications of all those constituents. It enables researchers and scientists to get informed of the designs to improve existing utilization of biomass in an efficient manner and deliver better products at lower cost.The volume isuseful reference for professionals, researchers, industrial practitioners, graduate students and senior undergraduates in the fields of polymer science, bioscience and bioengineering. It also provides an in-depth reference for biomass processors and fabricators and for industry sectors utilizing biomass such as packaging, sensors, film manufacturers, medical device manufacturers and biomedical engineers.
Handbook of Emerging Materials for Semiconductor Industry
by Laxman Raju Thoutam Shiromani Balmukund Rahi Young Suh Song Shubam Tayal T. S. Arun SamuelThe proposed book will be a “one-stop” place for all the young material researchers to understand the recent and reliable material making process, characterization, and reliability test tools. The proposed book is designed to provide basic knowledge to understand and analyse structure-property relationship for reliable emerging material systems for next generation of semiconductor technologies.The book is suggested to engineers and scientists across the world working on various new and novel materials for reliable semiconductor device applications. The book is expected to serve as a reference guide for young scientists and engineers in the field of material science and electronic engineers to acquire latest state-of-art experimental and computational tools to encourage their research activities.Since the scope of the book is generic, the book can be referred by all the students of science and engineering students to create a common awareness about the latest material systems and state-of-art characterization tools that have been broadly utilized to study the physical and chemical properties of different material systems.It introduces the readers to a wide variety of new emerging materials systems including their synthesis, fabrication, measurement, reliability test, modelling and simulations with in-depth analysis of selective applications.This book contains the state-of-art research updates in the various fields of semiconductor, artificial intelligence (AI), bio-sensor, biotechnology, with respect to reliable material research. Therefore, various students who are eager to get a job in semiconductor/AI/Autonomous car/biotechnology are strongly recommended to read this book and learn about related state-of-art knowledge.
Handbook of Oncobiology: From Basic to Clinical Sciences
by Nirmal K. Ganguly Rakesh Kumar R. C. SobtiThis Handbook on cancer biology comprehensively reviews the current status of the oncobiology of major cancer types, cancer detection and treatment strategies, principles and processes of cancer drug development, and nanomedicine and other emerging cancer medicine applications to cancer diagnosis and treatment. The book also provides practical and implementable nutritional guidance in cancer prevention, treatment, and quality of life for cancer survivors. It discusses pharmacogenetics strategies for predicting cancer prognosis and treatment exposure, response, and toxicity. Further, it presents bioinformatics approaches for predicting anti-cancer drugs and drug combinations based on the multi-omic data, including transcriptomics, toxicogenomics, functional genomics, and biological networks. The Handbook also examines major factors and pathways that regulate cancer stem cells development and discusses potential targeted therapy for cancer stem cells. The book explores the application of the CRISPR/Cas9-based gene-editing technique in basic cancer research, diagnosis, and treatment of cancer. This Handbook is an invaluable source for oncologists, researchers, public health specialists, epidemiologists, and policy makers.
The Handbook of Berber Linguistics (Springer Handbooks in Languages and Linguistics)
by Alireza Korangy Karim BensoukasThis handbook is the largest and most comprehensive publication on Berber linguistics to date, covering the variety of Berber dialects and related linguistics trends. Extensive and diverse at thematic and theoretical levels, with the aim of deepening students and scholars' understanding of the workings of Berber as a linguistic phenomenon, it explores a multitude of angles through which the diachronic and synchronic intricacies of Berber varieties can be examined. It enables a better understanding of the issues in the various components of North African languages, as well as their theoretical and typological significance and implications. The work covers phonology and phonetics, morphology and syntax, semantics and pragmatics, socio-linguistics and dialectology, language teaching and psycholinguistics, lexicology, language contact and comparative linguistics, historical linguistics and etymology. Sub-themes explored include prosody, ideophones (and expressive language in general), morpho-syntactic categories, sociolinguistic variation and several other seminal interdisciplinary explorations. The chapters reflect the diversity of Berber varieties and include up-to-date scholarship by leading Berberists, with varieties including Figuig, Kabyle, Senhaja, Siwa, Standard Moroccan Amazigh, Tamazight, Tarifit, Tashlhit, Touareg, Tunisian Berber, Znaga, as well as Proto-Berber. A large geographical territory is covered, including Algeria, Egypt, Libya, Mali, Mauritania, Morocco, and Tunisia. With contributions from these Berber-speaking countries and their diaspora, there are also chapters from prominent Berber scholars from America, Australia and Europe. To this end, the volume includes perspectives and theories from different schools of linguistics. In including original French contributions and English translations of research from top scholars in the field, the book includes another vital dimension in terms ofthe resources, and sources. As a comprehensive reference, this work is of interest to North Africanists from various disciplines, including anthropologists, linguists, and sociologists, but particularly linguists interested in endangered languages, and those working on the historical and comparative study of the Afroasiatic language phylum.
Essentials of Navigation: A Guide for Marine Navigation
by An Li Hongwei Bian Heng Ma Rongying WangThis book gives a basic introduction to navigation, from key concepts, basic principles, main technologies, equipment systems to the knowledge frame of navigation. The ten chapters fall into three parts: Chapters I~III introduce the elementary knowledge of navigation; Chapters IV~IX are devoted to the basic principles, and the optimization principle of integrated navigation as well; and Chapter X discusses the application of marine navigation, indicating the basic outline of the marine navigation system. The book clearly reflects the systematic idea of navigation knowledge from multiple perspectives, which is helpful for readers to build a holistic understanding of navigation from the concept, principle, characteristics, technology to the equipment system. At the end of each chapter, reflections beyond the fundamental knowledge of navigation are included to help readers further develop their scientific thinking and general literacy. This book is written primarily for students majoring in navigation, and it may also be of interest to researchers and practitioners engaged in navigation.
Games, Decisions, and Markets (New Frontiers in Regional Science: Asian Perspectives #74)
by Yasuhiro SakaiThis book critically discusses the historical backgrounds and new developments of the theories of games, decisions, and markets, with many possible applications to social and economic problems. Consisting of three connected parts, the book sheds new light on the role of merchants in the market economy under conditions of risk and uncertainty. Part I begins with the question of why and how John von Neumann and Oskar Morgenstern did joint work in game theory, namely, the theoretical study of strategic interactions among several decision makers. The duel between Sherlock Holmes and Professor Moriarty in Conan Doyle's famous detective story is recalled as a great inducement to Neumann and Morgenstern to invent zero-sum, two-person games. More general non-zero-sum games and associated Nash solutions are then discussed in relation to the generation-gap problem between a young couple and an elderly couple. Part II explores a set of very fundamental problems of individual decision making. Thetwo famous axioms of revealed preference ― Samuelson's weak axiom and Houthakker's axiom ― are skillfully connected and empirically reevaluated by the introduction of certain regularity conditions. The revealed preference approach is then extended from the original commodity space to the dual price space. Such dual treatment in microeconomics is further applied to the theory of cost and production, with the decomposition of the total factor price effect into the substitution and scale effects. Part III turns the reader’s attention to the interdependence of several markets. The almost forgotten Hicks–Morishima approach is newly revived with graphical illustrations of traded goods. The well-known Jones–Kemp approach to international trade is boldly expanded into the world of risk and uncertainty. Some striking results in comparative static analysis are derived, with favorable implications for the real world.
Indian Metallurgy: The Platinum Years (Indian Institute of Metals Series)
by Amol A. Gokhale R. Divakar S. V. S. Narayana Murty S. SrikanthThe book marks the Platinum Jubilee of the Indian Institute of Metals, closely matching independent India's age. It is envisaged as a compilation of technical articles tracing the birth and growth trajectory of metallurgical science, engineering and technology in the nation, attempting a degree of prognostication covering the next quarter of a century. It contains the essence of the metallurgical research and development and industrial progress India has witnessed in the last 75 years. This book comprises technical articles written by industry leaders and eminent technocrats. It includes overviews by distinguished researchers who have strived to build foundations of new metallurgical research and engineering fields. It includes learned writings of persons associated with premier institutions heavily dependent on metallurgy and materials. They have made seminal contributions by nurturing the growth of metallurgical research and industrial production or have made first-hand contributions to building the great organisations we have today. Coinciding with the Platinum Jubilee year of the Indian Institute of Metals, this book brings out the enormous efforts of these individuals representing their organisations to share insights that led to their success as an entity. Similarly, several professionals who significantly contributed to the understanding of metallurgical engineering, have held important positions and steered the national strategic programmes or academically nurtured students in their illustrious careers also share their journey in this book. This book chronicles the significant advances made in the field of metallurgical science, engineering and technology in India, presenting the historical perspective and prospects in the format of a technical volume.
Polysaccharide Based Films for Food Packaging: Fundamentals, Properties and Applications
by Syed Zameer Hussain Tawheed Amin Sajad Mohd Wani H. R. NaikThis book offers an extensive overview of the current and future potential of polysaccharides-based films, providing in-depth coverage of the fundamentals and basics of polysaccharide-based films.Aimed at students, scholars, scientists, and food packaging professionals, this book delves into the properties and applications of polysaccharide-based edible films in the food packaging industry. It provides insights and pathways for widening the applications of polysaccharide-based films to maximize their benefits in various industries and research institutes worldwide. With a wealth of scientific knowledge presented in an organized manner, this book serves as a valuable reference for researchers and professionals in food and pharmaceutical industries, as well as those in research and development (R&D) institutes.
Place, Catholicism and Violence: The Construction of Place in Caracas’ Barrios
by Gabriela Quintana VigiolaThis book explores the interwoven nature of place, Catholicism and violence in Caracas’ barrios. Using interdisciplinary perspectives to investigate themes of urban space, meaning as a psychosocial construct, criminal violence, and religiosity as culture, this book uncovers the underlying complexities of turning spaces into places through the built form, activities in the urban space and the meanings associated with it. Fundamental elements in the construction of place are used to understand the ways in which barrio residents conceive and construct the physicality of the private, public and religious spaces; how residents use the physical spaces of the barrios; and the psychosocial meanings residents associate with the spaces and activities. Using rich qualitative data and a case study design, the book relies on audio-visual data and interviews with organisers, residents and key participants in Petare, the largest barrio conglomeration in Caracas and Venezuela. Qualitative thematic analysis of participants’ experiences of Catholicism, violence and, ultimately, the construction of place exposes a unique argument: that meaningful urban spaces are embedded with emotions, memories, relationships, experiences and meanings, which turn them into places.
Advances in Vision Research, Volume IV: From Basic to Translational Research — Developing Diagnostics and Therapeutics for Genetic Eye Diseases (Essentials in Ophthalmology)
by Gyan Prakash Takeshi IwataThis fourth volume in the series Advances in Vision Research describes importance advancements in basics to translational research, including new therapeutics for genetic eye diseases. Recent US FDA approval of the first gene therapy for an inherited retinal disease, due to a mutation in the RPE65 gene, has led to an upsurge in translational eye research. The coverage in this volume includes corneal diseases, myopia, cataract, glaucoma, inherited retinal diseases, inherited optic neuropathy, and other genetic eye diseases. New developments such as the application of artificial intelligence in translational eye research are also discussed. All chapters are written by leading researchers working on eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume IV will be a major resource for all researchers, clinicians, clinical researchers, andallied eye health professionals with an interest in eye diseases around the globe. The first two volumes in the series described the state of the art in genetic eye research in Asia and the Pacific while the third focused on progress in Europe and the United States.
A Decade in Sino-Soviet Diplomacy: The Diaries of Liu Zerong, 1940–49
by David BrophyThis book will illuminate Xinjiang studies as never before, publishing for the first time the complete diaries of Liu Zerong, governor of Xinjiang during World War II, illuminating the origin of contemporary policies for smaller ethnic groups in the new China that emerged in 1949. The diaries are introduced with a biographical study of Liu, and a discussion of the historical context of World War II and the post-war situation in Xinjiang, which was divided into rival spheres of KMT control, and the Soviet-aligned East Turkistan Republic. Both in the Moscow embassy, and in the provincial administration of Ürümchi, Liu Zerong was Republican China’s chief Russian-speaking representative, whose task it was to engage on a daily basis with his Soviet counterparts. His extensive diaries therefore offer a unique insight into this tense decade of Sino-Soviet diplomacy, and will be of interest to a wide range of scholars in fields of Chinese and international history. The accompanying set of essays by the world's leading Xinjiang scholars confirm this volume's status as a key text for scholars, policymakers and others seeking to understand Chinese policies in Xinjiang.
The Handbook of Cultural Linguistics (Springer Handbooks in Languages and Linguistics)
by Alireza KorangyBringing together a wide selection of work on cultural linguistics and pragmatics, this comprehensive handbook offers global, comparative insights into the field. Diversity does not always imply differences, but it also offers insights into surprising similarities and parallels when it comes to expressions. By the same token, this collection shows that when we see that linguistic differences, when they exist, stem from not merely language, but from the cultural and historical context that cultivates and nurtures them. Within that paradigm, then, this handbook locates the importance of philosophy, religion (or even the lack thereof), political affiliations, and so on, in forming expressions. In addition, comparisons with other models of cultural linguistics are undertaken. These trends provide readers with a comprehensive introduction to issues in cultural linguistics, addressing the peculiarities of the field under the rubric of localized studies, and speaking to the possibilities that exist in interpretation of what metaphors are. The book highlights the complexities that are so tightly interwoven into the fabric of every word and a sentence, across cultures and linguistic traditions. A must-have collection for anthropologists, philosophers, linguists, philologists, theoreticians, rhetoricians, and scholars of poetics, this is the one-stop reference in cultural linguistics.
Molecular Biomarkers for Cancer Diagnosis and Therapy
by Ranbir Chander Sobti Aastha Sobti Haruhiko SugimuraThis book presents recent advancements, challenges, and clinical implications of molecular biomarkers in various cancers. This book highlights the clinical applications of biomarkers are extensive for cancer risk assessment, screening and early detection of cancer, accurate diagnosis, patient prognosis, prediction of response to therapy, and cancer surveillance and monitoring response. It also explores the progress of predictive biomarkers as an adjunctive tool to tumor immunotherapy in effectively identifying the efficacy of immune checkpoint inhibitors and discusses their future directions in achieving precision immuno-oncology. Further, the book examines the combination of next-generation sequencing and advanced computational data analysis approaches in the understanding of the genomic underpinnings of cancer development and progression. Towards the end, the chapter discusses the role of some commonly investigated phytochemicals and their epigenetic targets that are of particularinterest in cancer prevention and cancer therapy. It is a must for researchers as well as advanced students and physicians in the field of cancer and clinical oncologists.