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Lung Surfactants: Basic Science and Clinical Applications (Lung Biology in Health and Disease)
by Knud Erik SkoubyIntegrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease. Manage neonatal respiratory distress syndrome (RDS), acute respiratory distress syndrome (ARDS), and acute lung injury more effecti
Strengthening of Ceramics: Treatments: Tests, and Design Applications (Manufacturing Engineering and Materials Processing)
by null Henry Paul KirchnerThis book presents the descriptions of individual treatments and resulting improvements in the strength of polycrystalline ceramics and oxide single crystals. It provides information on potential applications, limitations of the treatments, design considerations, and costs.
Indo-Pacific and ASEAN: New Balances and New Challenges for Asian Integration and Stability (Indo-Pacific in Context)
by Claire Thi Liên Tran, Suthiphand Chirathivat and Prabir DeThis book examines Indo-Pacific issues from a Southeast Asian perspective and goes beyond discourses such as ASEAN–China or ASEAN–US–China. It analyses the new regional balances in the ASEAN and Indo-Pacific region at the diplomatic, strategic and economic levels while taking into account the ongoing uncertainty of the international order, reshaped by the post COVID-19 crisis and characterised by the increasingly adversarial China-US relations, the sensitive context of South China Sea and Taiwan crisis and the impact of the war between Russia and Ukraine. It highlights Indo-Pacific not only from a geostrategic angle but an economic one, considering ASEAN amidst competing connectivity strategies and integration challenges.The book offers an inclusive outlook capturing diversity and convergence of strategies in a key region where the stage of tomorrow’s global order will be decided. It will be of great interest to scholars and researchers of politics and international relations and Area Studies, especially Southeast-Asian Studies and Indo-Pacific Studies.
Soil Mechanics Fundamentals and Applications
by null Isao Ishibashi null Hemanta HazarikaHow Does Soil Behave and Why Does It Behave That Way?Soil Mechanics Fundamentals and Applications, Second Edition effectively explores the nature of soil, explains the principles of soil mechanics, and examines soil as an engineering material. This latest edition includes all the fundamental concepts of soil mechanics, as well as an introduction to
Active Learning in Secondary and College Science Classrooms: A Working Model for Helping the Learner To Learn
by null Joel Michael null Harold I. ModellThe working model for "helping the learner to learn" presented in this book is relevant to any teaching context, but the focus here is on teaching in secondary and college science classrooms.Specifically, the goals of the text are to: *help secondary- and college-level science faculty examine and redefine their roles in the classroom; *define for science teachers a framework for thinking about active learning and the creation of an active learning environment; and *provide them with the assistance they need to begin building successful active learning environments in their classrooms. Active Learning in Secondary and College Science Classrooms: A Working Model for Helping the Learner to Learn is motivated by fundamental changes in education in response to perceptions that students are not adequately acquiring the knowledge and skills necessary to meet current educational and economic goals. The premise of this book is that active learning offers a highly effective approach to meeting the mandate for increased student knowledge, skills, and performance. It is a valuable resource for all teacher trainers in science education and high school and college science teachers.
Soil and Water Contamination
by null Marcel van PerkSoil and Water Contamination, Second Edition gives a structured overview of transport and fate processes of environmental contaminants. Providing a structured overview of transport and fate processes of environmental contaminants, this textbook approaches the environmental issues of soil and water contamination from a spatial and earth science point of view. The new edition contains new material on pesticides and pharmaceutical contaminants and a greater number of exercises, case studies, and examples. It covers topics essential to understanding and predicting contaminant patterns in soil, groundwater, and surface water and contributes to the formation of a solid basis for adequate management and control of soil and water pollution and integrated catchment.
The Art and Science of Lecture Demonstration
by null C.A TaylorAs a means of conveying the excitement of science from one generation to the next, the lecture demonstration is one of the most powerful tools at the disposal of the modern science teacher. The interest of the young aspiring scientist is aroused not by dull textbook recitation, but by the enthusiastic lecturer with a range of demonstrations that il
Fatigue Life of Riveted Steel Bridges
by null Björn ÅkessonMany old riveted railway bridges are replaced too soon due to a general lack of knowledge about the expected life span. This indicates the need for more information on fatigue and brittle fracture of riveted bridges. This book unveils extensive research and literature results on riveted bridges' fatigue live and shows how to take fatigue properly i
Methods in Brain Connectivity Inference through Multivariate Time Series Analysis (Frontiers in Neuroengineering Series)
by Koichi Sameshima Luiz Antonio BaccaláInterest in brain connectivity inference has become ubiquitous and is now increasingly adopted in experimental investigations of clinical, behavioral, and experimental neurosciences. Methods in Brain Connectivity Inference through Multivariate Time Series Analysis gathers the contributions of leading international authors who discuss different time series analysis approaches, providing a thorough survey of information on how brain areas effectively interact. Incorporating multidisciplinary work in applied mathematics, statistics, and animal and human experiments at the forefront of the field, the book addresses the use of time series data in brain connectivity interference studies. Contributors present codes and data examples to back up their methodological descriptions, exploring the details of each proposed method as well as an appreciation of their merits and limitations. Supplemental material for the book, including code, data, practical examples, and color figures is supplied in the form of downloadable resources with directories organized by chapter and instruction files that provide additional detail.The field of brain connectivity inference is growing at a fast pace with new data/signal processing proposals emerging so often as to make it difficult to be fully up to date. This consolidated panorama of data-driven methods includes theoretical bases allied to computational tools, offering readers immediate hands-on experience in this dynamic arena.
Cleaning Validation Manual: A Comprehensive Guide for the Pharmaceutical and Biotechnology Industries
by null Syed Imtiaz HaiderDuring the past decades, enormous progress and enhancement of pharmaceutical manufacturing equipment and its use have been made. And while there are support documents, books, articles, and online resources available on the principles of cleaning and associated processing techniques, none of them provides a single database with convenient, ready-to-use training tools. Until now. Cleaning Validation Manual: A Comprehensive Guide for the Pharmaceutical and Biotechnology Industries elucidates how to train the man power involved in development, manufacturing, auditing, and validation of bio pharmaceuticals on a pilot scale, leading to scale-up production.With over 20 easy-to-use template protocols for cleaning validation of extensively used equipments, this book provides technical solutions to assist in fulfilling the training needs of finished pharmaceutical manufacturers. Drawing on the authors’ more than two decades of experience in the pharmaceutical and biotech industries, the text offers hands-on training based on current approaches and techniques. The book does not merely provide guidelines or thought processes, rather it gives ready-to-use formulas to develop Master Plan, SOPs, and validation protocols. It includes cleaning procedures for the most commonly used equipment in various manufacturing areas and their sampling points, using a pharmaceutical manufacturing site with both sterile and non-sterile operations as the case facility. It also provides the training guidelines on downloadable resources to enable users to amend or adopt them as necessary.Grounded in practicality, the book’s applicability and accessibility set it apart. It can be used as a guide for implementing a cleaning validation program on site without the help of external consultants, making it a resource that will not be found collecting dust on a shelf, but rather, referred to again and again.
Textbook of Erectile Dysfunction
by Culley C Carson Roger S KirbyErectile dysfunction (ED) affects 20-30 million American men, most of whom are over 50 years of age. In a UK-based study, 32% of British men had difficulty obtaining an erection, 20% with maintaining an erection. In recent years the physiology and pathophysiology of ED have changed our understanding of what ED is from a purely psychological-b
Inhalation Studies: Foundations and Techniques
by null Robert F. PhalenThis significantly updated and expanded new edition presents the scientific foundations of inhalation research essential to the design and conduct of toxicologic studies. It incorporates the major advances that have been made in the field, including recent advances in biology and the rapidly increasing global concerns and studies on particulate air
Barrier Systems for Environmental Contaminant Containment and Treatment
by null Calvin C. Chien null Hilary I. Inyang null Lorne G. EverettContainment and permeable reactive barriers have come full circle as an acceptable environmental control technology during the past 30 years. As interest shifted back toward containment in the 1990s, the industry found itself relying largely on pre-1980s technology. Fortunately, in the past 10 years important advances have occurred in several areas
Critical Limb Ischemia
by Marc Bosiers Peter A. SchneiderCovering both noninvasive and surgical treatment alternatives, Critical Limb Ischemia defines practical guidelines for a multidisciplinary approach to critical limb ischemia and follows a step-by-step description of the latest techniques.Topics covered include:Balloon angioplasty and stenting Cryoplasty Pharmacotherapy Topical therapies combined wi
Neuroprosthetics: Principles and Applications (Rehabilitation Science in Practice Series)
by null Justin C. SanchezMaster the tools of design thinking using Neuroprosthetics: Principles and Applications. Developed from successfully tested material used in an undergraduate and graduate level course taught to biomedical engineering and neuroscience students, this book focuses on the use of direct neural sensing and stimulation as a therapeutic intervention for complex disorders of the brain. It covers the theory and applications behind neuroprosthetics and explores how neuroprosthetic design thinking can enhance value for users of a direct neural interface. The book explains the fundamentals of design thinking, introduces essential concepts from neuroscience and engineering illustrating the major components of neuroprosthetics, and presents practical applications. In addition to describing the approach of design thinking (based on facts about the user’s needs, desires, habits, attitudes, and experiences with neuroprosthetics), it also examines how effectively "human centered" neuroprosthetics can address people’s needs and interactions in their daily lives. Identifying concepts and features of devices that work well with users of a direct neural interface, this book: Outlines the signal sensing capabilities and trade-offs for common electrode designs, and determines the most appropriate electrode for any neuroprosthetic application Specifies neurosurgical techniques and how electronics should be tailored to capture neural signals Provides an understanding of the mechanisms of neural–electrode performance and information contained in neural signals Provides understanding of neural decoding in neuroprosthetic applications Describes the strategies that can be used to promote long-term therapeutic interventions for humans through the use of neuroprosthetics The first true primary text for undergraduate and graduate students in departments of neuroscience and bioengineering that covers the theory and applications behind this science, Neuroprosthetics: Principles and Applications provides the fundamental knowledge needed to understand how electrodes translate neural activity into signals that are useable by machines and enables readers to master the tools of design thinking and apply them to any neuroprosthetic application.
Physics and Chemistry of Nano-structured Materials
by null Shihe YangThe development of nanostructured materials represents a new and fast evolving application of recent research in physics and chemistry. Novel experimental tools coupled with new theory have made this possible. Topics covered in this book include nanocrystals, semiconductor heterostructures, nanotubes, nanowires, and manipulation and fabrication tec
Guide to Optimal Operational Risk and BASEL II
by null Ioannis S. Akkizidis null Vivianne BouchereauGuide to Optimal Operational Risk and Basel II presents the key aspects of operational risk management that are also aligned with the Basel II requirements. This volume provides detailed guidance for the design and implementation of an efficient operational risk management system. It contains all elements of assessment, including operational risk i
Climate Change and Global Food Security
by Rattan Lal B. A. Stewart David O. HansenIn order to feed their burgeoning populations, developing nations will need to double cereal production by the year 2050. This increase will have to come from existing land, as little potential exists for bringing new land under cultivation -- a daunting prospect when one realizes that increased use and significantly higher concentrations of carbon
Rapid Load Testing on Piles: Interpretation Guidelines
by null Paul Holscher null Henk Brassinga null Michael Brown null Peter Middendorp null Maarten Profittlich null Frits A. van TolA Rapid Load Test (RLT), developed to determine the initial stiffness and bearing capacity, is an economical and practical alternative to a Static Load Test (SLT). The broad application of RLT, however, was hampered by uncertainty about the interpretation of the test results. This book offers clear guidance on the available analysis techniques and
Innovative Solutions: What Designers Need to Know for Today's Emerging Markets
by Apala Lahiri Chavan Girish V. PrabhuExpanding into emerging markets brings with it a specific set of challenges for designing products and services. Not only do cultural differences play a role in what, how, and why customers behave the way they do, but existing technologies, distribution channels, and the wants and needs of consumers become additional challenges when establishing ma
Chemistry of Protein and Nucleic Acid Cross-Linking and Conjugation
by null Shan S. Wong null David M. JamesonSince the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nucleic acid and protein interactions using nucleic acid cross
Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting (Chapman & Hall/CRC Biostatistics Series)
by Qi Jiang H. Amy XiaState-of-the-Art Methods for Drug Safety AssessmentResponding to the increased scrutiny of drug safety in recent years, Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both clinical trials and observational studies in biopharmaceutical product deve
Revising Green Infrastructure: Concepts Between Nature and Design
by Daniel Czechowski Thomas Hauck Georg Hausladen Roderick M. KramerConsider this … How do we handle the convergence of landscape architecture, ecological planning, and civil engineering? What are convenient terms and metaphors to communicate the interplay between design and ecology? What are suitable scientific theories and technological means? What innovations arise from multidisciplinary and cross-scalar approaches? What are appropriate aesthetic statements and spatial concepts? What instruments and tools should be applied? Revising Green Infrastructure: Concepts Between Nature and Design examines these questions and presents innovative approaches in designing green, landscape or nature as infrastructure from different perspectives and attitudes instead of adding another definition or category of green infrastructure. The editors bring together the work of selected ecologists, engineers, and landscape architects who discuss a variety of theoretical aspects, research projects, teaching methods, and best practice examples in green infrastructure. The approaches range from retrofitting existing infrastructures through landscape-based integrations of new infrastructures and envisioning prospective landscapes as hybrids, machines, or cultural extensions.The book explores a scientific functional approach in landscape architecture. It begins with an overview of green functionalism and includes examples of how new design logics are deducted from ecology in order to meet economic and environmental requirements and open new aesthetic relationships toward nature. The contributors share a decidedly cultural perspective on nature as landscape. Their ecological view emphasizes the individual nature of specific local situations. Building on this foundation, the subsequent chapters present political ideas and programs defining social relations toward nature and their integration in different planning systems as well as their impact on nature and society. They explore different ways of participation and cooperation within cities, regions, and nations. They then describe projects implemented in local contexts to solve concrete problems or remediate malfunctions. These projects illustrate the full scope presented and discussed throughout the book: the use of scientific knowledge, strategic thinking, communication with municipal authorities and local stakeholders, design implementation on site, and documentation and control of feedback and outcome with adequate indicators and metrics.Although diverse and sometimes controversial, the discussion of how nature is regarded in contrast to society, how human-natural systems could be organized, and how nature could be changed, optimized, or designed raises the question of whether there is a new paradigm for the design of social relations to nature. The multidisciplinary review in this book brings together discussions previously held only within the respective disciplines, and demonstrates how they can be used to develop new methods and remediation strategies.
Treatment of Pediatric Neurologic Disorders
by Harvey S. Singer Eric H. Kossoff Adam L. Hartman Thomas O. CrawfordThis reference discusses state-of-the-art methods for the management of children with conditions affecting the nervous system-providing over 80 chapters that outline direct, logical approaches to numerous pediatric neurologic disorders using clear tables, algorithms, and figures for quick reference to key material.
Introduction to the Simulation of Dynamics Using Simulink (Chapman & Hall/CRC Computational Science)
by null Michael A. GrayDesigned for undergraduate students in the general science, engineering, and mathematics community, Introduction to the Simulation of Dynamics Using Simulink (R) shows how to use the powerful tool of Simulink to investigate and form intuitions about the behavior of dynamical systems. Requiring no prior programming experience, it clearly explains how to transition from physical models described by mathematical equations directly to executable Simulink simulations.Teaches students how to model and explore the dynamics of systemsStep by step, the author presents the basics of building a simulation in Simulink. He begins with finite difference equations and simple discrete models, such as annual population models, to introduce the concept of state. The text then covers ordinary differential equations, numerical integration algorithms, and time-step simulation. The final chapter offers overviews of some advanced topics, including the simulation of chaotic dynamics and partial differential equations.A one-semester undergraduate course on simulationWritten in an informal, accessible style, this guide includes many diagrams and graphics as well as exercises embedded within the text. It also draws on numerous examples from the science, engineering, and technology fields. The book deepens students' understanding of simulated systems and prepares them for advanced and specialized studies in simulation.