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Hollywood North: A Novel in Six Reels
by Michael Libling&“Libling&’s assured, quietly menacing debut [is] based on his World Fantasy Award–nominated novella of the same title. . . . Fans of Stand by Me and the like will find much to enjoy.&” —Publishers Weekly It&’s the 1960s, and Gus Berry is coming of age in Trenton, a small town on the north shore of Lake Ontario. The place isn&’t known for much—unless you count the menacing stray dogs, plant explosions, plane collisions, and regular drownings. The adults seem to take it all in stride, but Gus can&’t shake the feeling of impending doom. His friend Annie Barker doesn&’t share Gus&’s dark thoughts; she believes in things. So Gus goes about his days, surviving school, trying to live up to his widowed mother&’s expectations, and growing increasingly obsessed with movies and TV shows. Indeed, he scripts his life to make it way more exciting and adventurous than it actually is. Gus is clearly a boy who wants things, which makes Jack Levin the perfect friend. He&’s a local hero famous for finding stuff : a message in a bottle, a meteorite, a long-lost wedding ring. And when Jack makes his most mysterious discovery yet, Gus and Annie are drawn with him into an investigation of Trenton&’s past. Guided by their curiosity, they soon uncover a malignant darkness behind the town&’s senseless tragedies. In Hollywood North, World Fantasy Award–nominated author Michael Libling &“spins a tale of movies and memories, nightmares and nostalgia, with such a frightening secret at its core, that you&’ll understand why, even though you can go home again, you might end up wishing you didn&’t&” (Ian Rogers, author of Every House Is Haunted). &“[A] fine first novel . . . Bradbury might have sketched out this mode in the darker parts of Dandelion Wine and the entirety of Something Wicked This Way Comes, but contemporary authors such as Libling are showing us refinements of sensibility and sense of wonder that the old Waukeganian never dreamed of.&” —Locus
The Food of Taiwan: Recipes from the Beautiful Island
by Cathy ErwayThe acclaimed food writer offers an insider's look at Taiwanese cooking from home-style dishes to authentic street food in &“this appetizing collection&” (Publisher Weekly, starred review). While certain dishes from Taiwan are immensely popular, like steamed buns and bubble tea, much of the cuisine still remains relatively unknown in America. In The Food of Taiwan, Taiwanese-American Cathy Erway, the acclaimed blogger and author of The Art of Eating In, explores the rich culture, history, and culinary traditions of Taiwan—including nearly 100 recipes. Recipes range from familiar dishes, such as Pork Belly Buns, Three Cup Chicken, and Beef Noodle Soup, to more uncommon fare, like the Stuffed Bitter Melon, Oyster Noodle Soup, and Dried Radish Omelet. Tantalizing food photographs intersperse with beautiful shots of Taiwan&’s coasts, mountains, and farms as well as images of bustling city scenes, making this book just as enticing to flip through as it is to cook from.
Mehrsprachigkeit im sprachbildenden Mathematikunterricht: Gelingensbedingungen und didaktische Potenziale in sprachlich heterogenen Klassen (Dortmunder Beiträge zur Entwicklung und Erforschung des Mathematikunterrichts #53)
by Ángela UribeIn einem verstehensorientierten sprachbildenden Mathematikunterricht wird Sprache als Denkwerkzeug und somit als Schlüssel zum konzeptuellen Verständnis verstanden. Vor diesem Hintergrund stellt sich die Frage nach der Rolle anderer Sprachen neben der Unterrichtssprache im Lehr-Lern-Prozess. Insbesondere in einer mehrsprachigen Gesellschaft – wie Deutschland – treffen im Unterricht diverse Sprachen aufeinander und die Lernenden bringen eine Vielzahl von Ressourcen als Teil ihrer sprachlichen Repertoires mit, die über die Unterrichtssprache hinausgehen. Diese mehrsprachigen Repertoires der Lernenden können gerade für die Bedeutungskonstruktion beim Aufbau von konzeptuellem Verständnis eine wertvolle Ressource darstellen. Das vorliegende Buch trägt dazu bei, den Einbezug dieser vielfältigen Repertoires im Mathematikunterricht in sprachlich heterogenen Regelklassen zu konkretisieren. Es bietet dabei sowohl unmittelbare Ansatzpunkte für die Praxis als auch eine solide Grundlage für zukünftige Untersuchungen, die darauf abzielen, den Mathematikunterricht in einer zunehmend mehrsprachigen Welt weiter zu verstehen und zu verbessern. Das Buch markiert einen bedeutenden Schritt vorwärts im Einbezug von Mehrsprachigkeit als Ressource im Mathematikunterricht und setzt damit ein starkes Signal für eine inklusive und weltoffene Didaktik.
Emerging Information Security and Applications: 5th International Conference, EISA 2024, Changzhou, China, October 18–19, 2024, Proceedings (Communications in Computer and Information Science #2266)
by Liqun Chen Javier Lopez Wenjuan LiThis book constitutes the refereed proceedings of the 5th International Conference on EISA--Emerging Information Security and Applications, EISA 2024, held in Changzhou, China, during October 18–19, 2024. The 15 full papers and 3 short papers included in this book were carefully reviewed and selected from 52 submissions. The topics covered adversarial techniques, intrusions that may threaten the security of various assets, including information and applications, have become more complex.
Risky Alcohol Consumption among Adolescents: Manual for the Implementation of a Brief Motivational Intervention
by Silke Diestelkamp Rainer ThomasiusThis manual provides expert knowledge on theory and practice for conducting a motivational brief intervention with adolescents after alcohol intoxication, with the aim of promoting low-risk use of alcohol. Enriched with examples and tips on how to proceed in difficult (conversational) situations, users receive practical instructions on how to conduct a theory-based and evaluated motivational patient interview, instructions for a parent interview and all relevant materials for implementation. The intervention was developed and evaluated as part of a research project funded by the Federal Ministry of Education and Research (BMBF) and is based on the bridge conversation of the alcohol prevention programme "HaLT - Hart am LimiT".
Osteonecrosis
by Lynne C. Jones Kyung-Hoi Koo Michael A. Mont Quanjun CuiOsteonecrosis is a disease caused by reduced blood flow to bones in the joints, including the hip, knee, shoulder, and ankle. The disease, which is usually progressive and leads to joint failure, occurs in young adults aged from their twenties to their fifties. The pathogenesis of osteonecrosis is still unclear, and treatment remains controversial. This book provides up-to-date and comprehensive information on the pathophysiology, etiology, diagnosis, classification, and treatment of osteonecrosis. The role of various imaging modalities is considered, and both non-surgical and surgical treatment approaches are clearly explained. The contributions, all from experts in the field, are based on presentations at leading international meetings during the past 10 years and on peer-reviewed papers. The book will be of interest not only to clinical practitioners but also to those engaged in basic research.
Mars and the Earthlings: A Realistic View on Mars Exploration and Settlement (Space and Society)
by Muriel Gargaud Kirsi Lehto Michel Viso Cyprien VerseuxIn an era of public Mars fascination, this book offers an objective presentation of the challenges of crewed Mars missions and discusses scenarios of Mars settlements under scientific, technical, social, economic , ethical and political aspects. With the aim to make the reader comprehend what is plausible and what is at stake, the book tries to clarify misconceptions and half-truths spreading rapidly in the public. The authors argue that approximations and misinformation should be countered for two main reasons. First, to avoid missing out on the benefits that Mars exploration may bring, including major scientific discoveries and an inspiring, federative human endeavor. Second, to remediate dangerous delusions – such as the idea that humanity could be transferred there should the Earth become inhabitable in the near term. In preparation for this book a group of European, world-renowned scientists from fields as diverse as astronomy, planetology, geology, biology, philosophy, or economics, as well as astronauts and science-fiction writers, was gathered to discuss Mars missions ranging from near-term robotic missions, all the way to large-scale settlements and even the feasibility of terraforming. For each, they draw arguments from their domains of expertise to discuss what is feasible and what is desirable. The result provides researchers with an objective review of the field, policy makers with a reference to make informed decisions, and the general public with a tool to form educated opinions.
Where is Lindy's Voice?
by Melinda PetoEmbark on a magical journey alongside Lindy, a young explorer in search of her voice. In this enchanting tale, Lindy sets out to discover the wonders of the world around her, encountering happiness and beauty at every turn.As Lindy ventures through fantastical landscapes and encounters whimsical characters, she not only unravels the mysteries of the world but also unearths the power of her own voice. This joyful story sparks a sense of wonder and curiosity in young readers, inspiring them to embark on their own journey of self-discovery. With each page turned, children will be captivated by the charm and magic of Lindy&’s adventure, while also learning valuable lessons about finding their own unique voice in the world.
Yiannis The Global Warming Warrior
by Steve MansfieldFrom a small town in a quaint country emerges a young hero with big ideas. At just seven, Yiannis isn’t just aware of the looming threat of global warming; he’s ready to tackle it head-on. And guess what? He’s got some of the most inventive solutions up his sleeve. Embark on a global adventure with Yiannis and his resourceful dad as they traverse diverse landscapes, from the arid terrains of Africa to the icy realms of the North Pole. Their mission? To combat climate change with their unique inventions. Some solutions might have you reaching for a nose peg, while others could tantalize your taste buds—especially if you’re a fan of bananas. And wait till you hear about their groundbreaking eco-fuel! Blending factual insights with fictional fun, our dynamic duo also takes on challenges like reviving the dried-up Zambezi River for an African king and addressing the pressing issues of deforestation, plastic waste, and more in South America and the ocean’s depths. Yiannis’s tales are more than just stories; they’re a rallying cry for change. Dive into his adventures, and you too might be inspired to join the ranks of the Global Warming Warriors. Are you ready to make a difference?
Liberal Perspectives on Inclusion: Enlightenment Values and Debates on Equity and Democracy in the Classroom (Routledge Research in Special Educational Needs)
by Joseph MintzProviding a theoretical underpinning for the idea of inclusion within education, this book recognizes the fundamental role political values play in our understanding of inclusion in the classroom, providing a philosophical lens on the inherent tensions that exist within sociological perspectives on social justice, equity and diversity.Chapters address value tensions from the perspective of classical liberalism and the extent to which this can be reconciled with values pluralism and Berlin’s notions of negative and positive liberty. The book argues for a re-framing of inclusion as a process of negotiation between teachers, parents, children and young people which involves a recognition of the complex tradeoffs involved in working with difference in the classroom. These tensions are explored through a series of case studies of real-world dilemmas in the classroom, ultimately serving to highlight the ways in which varying political value positions, including liberalism, are inescapably embedded within the practice in education.Considering topics such as decolonization of the curriculum, freedom of speech and social justice, this seminal volume will be highly relevant for researchers, scholars and postgraduate students in the fields of inclusive education, special educational needs, philosophy of education, social justice and education and critical theory.
Taste of Broadway: Restaurant Recipes From Nyc's Theater District
by Carliss Retif PondFrom Sardi&’s to the Russian Tea Room, Broadway&’s most iconic restaurants take center stage in this collection of classic recipes. Since before Sinatra found his favorite table at Patsy&’s, New York City&’s Theater District has overflowed with the glamour of Broadway stars and the famous restaurants that cater to their appetites. For many audience members, the pre- or post-show meal is the most memorable part of a night out on The Great White Way. Taste of Broadway collects recipes from some of the most famous restaurants in the district, including the Algonquin, the Russian Tea Room, Sardi&’s, the &“21&” Club and many more. Full of photographs, quotes from bartenders and regulars, as well as Broadway restaurant history and lore, this book offers plenty of local color to savor.
Dogs: Their Fossil Relatives & Evolutionary History
by Xiaoming Wang Richard H. TedfordTwo noted paleontologists present a detailed portrait of the family Canidae across 40 million years of evolution in this illustrated volume. After decades of research and analysis, paleontologists Xiaoming Wang and Richard H. Tedford established the modern framework for understanding the evolutionary relationship of canids. Combining their work with Mauricio Antón's reconstructions of both extinct and extant species, Wang and Tedford now present a nuanced and visually stunning portrait of the origin and evolution of canids. The fossil record of the Canidae, particularly those from their birthplace in North America, are the strongest of their kind among known groups of carnivorans. Such a wonderfully detailed evolutionary history makes the canid an ideal model organism for the mapping of predator behavior and morphological specializations. With its innovative illustrated approach to this important branch of animal and fossil study, Dogs provides an unprecedented reference for anyone interested in the evolution of these fascinating animals.
Urban Views: 12 Quilts Inspired by City Living
by Cherri HouseThe bestselling author of City Quilts is back with &“12 projects in her graphic, modern and colorful style, all created with solid or near-solid fabrics&” (Down Under Quilts Magazine). Cherri House invites you to continue on her quilt making journey in her latest book Urban Views. In this collection of 12 all-new projects, you&’ll learn how to quilt with triangles as well as master a variety of innovative techniques. In the &“City Challenge,&” the author explores 4 more U.S. cities with new quilt designs. All of the projects are rendered in House&’s beloved signature style and will surely inspire sewists of every skill level. Beginner and experienced sewists alike can create modern, must-have quilts with innovative techniquesFeatures modern solid fabric quilt designs with a universal appeal, making them excellent gifts for men and women alike &“House comes down solidly on the side of solids, and with her imaginative designs, the fabrics soar.&”—Publishers Weekly
Rescuing Retirement: A Plan to Guarantee Retirement Security for All Americans
by Teresa Ghilarducci Tony JamesRetirement shouldn&’t be just for the rich: &“Finally, a practical plan to address Americans&’ lack of adequate retirement savings.&”—Michael Bloomberg Everyone deserves to be able to retire with dignity, but this core feature of the social contract is in jeopardy. Companies have swerved away from pensions, and most of the workforce has woefully inadequate retirement savings. If we don&’t act to fix this broken system, rates of impoverishment for senior citizens threaten to skyrocket, and tens of millions of Americans reaching retirement age in the coming decades will be forced to delay retirement and will experience a dramatic drop in their standard of living. In Rescuing Retirement, economist Teresa Ghilarducci and billionaire businessman Tony James offer a comprehensive yet simple plan to help workers save for retirement, increase retirement savings by earning higher returns, and guarantee lifelong income for everyone. Built on people&’s own money in individual Guaranteed Retirement Accounts, the plan requires no new taxes, no more bureaucracy, and no increase in the deficit. Speaking to Americans&’ growing anxiety about their ability to retire, Rescuing Retirement provides answers to anyone wanting to understand the growing movement to protect a period of life once considered a deserved time of rest and creativity and offers a practical guide to the future of secure retirement. &“Ghilarducci and James never slip into wonk-speak or jargon, and lay readers will appreciate the way the authors make sense of complex economic issues.&”—Publishers Weekly
Cutter and Bone (Midnight Classics Ser.)
by Newton Thornburg&“A thriller, and a whacking good thriller, too . . . shows how much can be done within a classic form by a writer who knows his business.&”—The New York Times Alex Cutter is a scarred and crippled Vietnam veteran, obsessed with a murder he&’s convinced his buddy, Richard Bone, witnessed. That it was committed by the powerful tycoon JJ Wolfe only makes Cutter even surer that Bone saw the unthinkable. Captivated by Cutter&’s demented logic, Bone is prepared to cross the country with Cutter in search of proof of the murder. Their quest takes them into the Ozarks—home base of the Wolfe empire—where Bone discovers that Cutter is pursuing both a cold-blooded killer, but also an even bigger and more elusive enemy. &“Tense, funny, and despairing . . . charged with a passion that makes even grotesques seem likeable and, more important, credible right up to the last, startling sentence.&”—Time &“May be the quintessential cult crime classic . . . continues to be cited by other writers as groundbreaking . . . The ending is pure Chinatown, with a dose of Easy Rider, and it leaves us reeling.&”—Booklist (starred review) Praise for Newton Thornburg &“A commanding writer of unusual delicacy and power.&”—The New Yorker &“A born storyteller.&”—St. Louis Post-Dispatch &“One of the truly great American writers of the 20th century.&”—The Guardian
Mary: The Merry Widows - Book One (The Merry Widows #1)
by Raine CantrellA mysterious man captivates a kindhearted medic in this historical western romance from the author of the Kincaids series.For widow Mary Inlow, there is little to mourn for her dead husband, the man who mocked her inability to bear him a child. Although she is haunted by nightmares, she is intent to start life anew. Mary becomes a reliable town medic.Living an accomplished and peaceful little life alongside her childhood friends, dubbed the Merry Widows, Mary is determined to take her sweet time entering back into the world as a free woman. She vows to never again cater to the demands of another man. That is until one shows up on her doorstep bloody, exhausted, and carrying his life on his shoulders.Desperately seeking medical help for his wounded little girl, Rafe McCade barges through Mary&’s front door in the worst shape of his life. Ushered into action by a child in need, Mary asks for little information of the frantic father, but his tender care of the child speaks volumes. McCade is forever in debt to Mary for rescuing his daughter. Yet the longer he stays in her home, the more he fears she may just rescue something money cannot repay: a piece of his soul he thought long dead.&“Raine Cantrell is a superb storyteller whose remarkable talent for recreating the West will hold you enthralled.&” —RT Book Reviews
Massachusetts Book of the Dead: Graveyard Legends and Lore (Haunted America)
by Roxie J. ZwickerA historical tour of the Bay State&’s oldest burial grounds—and the sometimes-spooky stories behind them. Massachusetts's historic graveyards are the final resting places for tales of the strange and supernatural. From Newburyport to Truro, these graveyards often frighten the living, but the dead who rest within them have stories to share with the world they left behind. While Giles Corey is said to haunt the Howard Street Cemetery in Salem, cursing those involved in the infamous witch trials, visitors to the Forest Hills Cemetery in Jamaica Plain enjoy an arboretum and a burial ground with Victorian-era memorials. One of the oldest cemeteries in Massachusetts, Old Burial Hill in Marblehead, has been the final resting place for residents for nearly 375 years. Author Roxie Zwicker tours the Bay State's oldest burial grounds, exploring the stones, stories and supernatural lore of these hallowed places. Includes photos
Haunted Portsmouth: Spirits and Shadows of the Past (Haunted America)
by Roxie J. ZwickerNew Hampshire&’s historic port town is no stranger to ghostly goings-on—from the local TV personality and author of Massachusetts Book of the Dead. A tour of Portsmouth&’s back alleys and docksides, filled with the lingering whispers and memories of generations long dead. Venture through the haunted past and present of Portsmouth, New Hampshire, if you dare. Before Portsmouth was a charming seaside community, it was a rough-and-tumble seaport. Hear phantom footsteps in the Point of Pines Burial Ground and mysterious voices at the Portsmouth Harbor Lighthouse, haunted by the ghost of its former keeper. Tour guide and hauntings expert Roxie Zwicker takes readers on a tour of the nation&’s third-oldest city, where buildings and street corners teem with ghostly stories and legends. Includes photos!
You Play the Girl: On Playboy Bunnies, Stepford Wives, Train Wrecks, & Other Mixed Messages
by Carina ChocanoNational Book Critics Circle Award Winner. &“With dazzling clarity, [Chocano&’s] commentary exposes the subliminal sexism on our pages and screens.&”—O, The Oprah MagazineAs a kid in the 1970s and 80s, Carina Chocano was confused by the mixed messages all around her that told her who she could be—and who she couldn&’t. She grappled with sexed up sidekicks, princesses waiting to be saved, and morally infallible angels who seemed to have no opinions of their own. It wasn&’t until she spent five years as a movie critic, and was laid off just after her daughter was born, however, that she really came to understand how the stories the culture tells us about what it means to be a girl limit our lives and shape our destinies.In You Play the Girl, Chocano blends formative personal stories with insightful and emotionally powerful analysis. Moving from Bugs Bunny to Playboy Bunnies, from Flashdance to Frozen, from the progressive &’70s through the backlash &’80s, the glib &’90s, and the pornified aughts—and at stops in between—she explains how growing up in the shadow of &“the girl&” taught her to think about herself and the world and what it means to raise a daughter in the face of these contorted reflections. In the tradition of Roxane Gay, Rebecca Solnit, and Susan Sontag, Chocano brilliantly shows that our identities are more fluid than we think, and certainly more complex than anything we see on any kind of screen.&“If Hollywood&’s treatment of women leaves you wanting, you&’ll find good, heady company in You Play the Girl.&”—Elle
The Wedding Menu
by Letizia LoriniFor fans of Tessa Bailey and Mia Sosa, highly acclaimed author Letizia Lorini brings a deliciously sexy, poignant, and laugh-out-loud funny rom-com set in the culinary world.One year ago, Amelie had it all. Nearly engaged to her high school sweetheart, close to her childhood best friend, and cooking at her dad&’s restaurant, her life was exactly what she&’d ordered. Until Ian, an opinionated wedding-hater, sat beside her at a wedding and proved she might like something off-menu. Now, Amelie is unemployed, single, and taking a break from her best friend. On top of it all, she&’s lost all contact with Ian. When she visits his hometown to teach at a weeklong cooking conference, she hopes for a fateful meet-cute. But their reunion is explosive when Amelie discovers Ian is the son of her father&’s business rival. Even bigger fiasco? He only wants to be her friend. Amelie has one week to change his mind, and if the truth of why her whole life fell apart remains hidden, their love story might even end with a wedding.
A Primer on Austrian Macroeconomics: Austrian Capital Theory for Macroeconomic Research and Teaching (Palgrave Studies in Austrian Economics)
by Antony P. MuellerThis book offers an accessible framework for macroeconomic modelling rooted in the capital theory of Austrian Economics. By distinguishing between the goods and monetary sides of the economy and exploring their interaction, the book provides a comprehensive macroeconomic model that integrates time preference and interest rates. It examines how monetary and fiscal policies can produce business cycles and how these cycles are influenced by central bank liquidity and financial market behaviour. Additionally, the book discusses the ways in which monetary and fiscal policies can prolong and intensify economic stagnation. Through its clear exposition, this book deepens the understanding of the conditions that determine the unsustainability of credit-driven economic expansions. It is essential reading for students and researchers in political economy, macroeconomics, monetary economics, and those interested in advancing Austrian Economics.
Competing Visions: Waiting for a Grand Strategic Shift
by Paul Dobrescu Flavia DurachThis book presents an in-depth and provoking analysis of the current global landscape and the challenges it presents for development. Offering a unique approach examining the implications of strategic uncertainty on strategies for development, it discusses contemporary challenges to the field, particularly those relating to crisis management. Positing that we live in an age of strategic uncertainty, the authors progress the notion that crisis responses require extensive and holistic strategic deliberation vis-à-vis economic and social considerations, short-term and long-term projections, as well as evaluations of domestic and international spheres of development. Tracing the infrastructure of globalization, the book acknowledges the need for medium-term strategies for each crisis but emphasizes that they must be intricately woven into a larger unitary vision, ultimately highlighting the critical role of strategic thinking in addressing complex challenges we face today.
The Origins of the Contemporary Global Order: From the Nineteenth Century to the Cold War
by Carl J. StrikwerdaThis book offers a new interpretation of the origins of the contemporary global order - the set of institutions and international practices created by the USA and its allies after the Second World War. Previous interpretations have argued that the USA played the predominant role in creating the global order to fight the Cold War against the Soviet Union. The author argues that a broader perspective is necessary to understand both the origins of the global order, and its ongoing tensions up until today, a perspective that includes the legacy of both world wars, the role of imperialism, and the alternative strategy of globally oriented economic blocs. The cooperative tradition in the founding of the global order and the contributions of nations besides the USA provides useful insights for those interested in the current global order and the challenges it faces from Russia and China.
AI Implementation in Radiology: Challenges and Opportunities in Clinical Practice (Imaging Informatics for Healthcare Professionals)
by Willem Grootjans Erik Ranschaert Mohammad H. Rezazade Mehrizi Tessa S. CookThis book describes change management in the context of implementing AI in medicine and radiology. Why do many medical institutions struggle to use AI in their clinical practice? What are the essential steps for and before an effective implementation of AI in radiology workflow? How can AI implementation trigger enduring improvements in the clinical process? The book shows how change management is crucial to effectively introduce AI to medicine and radiology, transform healthcare delivery and ensure a smooth transition while maximizing the benefits of AI and minimizing potential disruptions. Change management in the context of AI in medicine and radiology involves a systematic approach to identify, plan, implement, and evaluate the integration of AI technologies into healthcare systems. It engages the necessary stakeholders at the appropriate points in the process to ensure that change is implemented properly. By effectively managing the change, healthcare organizations can harness the potential of AI to enhance patient care, improve diagnosis accuracy, and optimize operational efficiency in radiology and other medical specialties. Throughout this change management process, organizations should prioritize ethical considerations, data privacy, and regulatory compliance to ensure that AI technologies are deployed responsibly and in accordance with relevant guidelines and regulations.
Protein Biomarkers: Discovery and Applications in Clinical Diagnostics
by Pranjal Chandra Sumit Kumar SinghThis book comprehensively reviews the fundamentals of biomarker discovery using mass-spectrometry-based proteomic and glycoproteomic methods. It also provides case studies of proteomic and glycoproteomic molecular signatures to illustrate the design and use of various mass spectrometry modes such as selected reaction monitoring (SRM), parallel reaction monitoring (PRM), and sequential window acquisition of all theoretical fragment ion spectra mass spectrometry (SWATH-MS). In turn, the book presents the challenges of the proteomic methods in biomarker discovery and approaches for overcoming these challenges by extending the performance by improving the sensitivity, throughput, and selectivity of the method. It also addresses the bottleneck of deriving useful biological interpretations from large multi-dimensional datasets emanating from these experiments by discussing data analysis pipelines and appropriate statistical analysis. Finally, a detailed discussion on the design, characterization, and application of protein/glycoprotein-based biosensors for clinical diagnostics is discussed. The book is intended to serve as a reliable resource for the students and researchers working in the area of biomarker discovery and validation using mass spectrometry-based methods and their subsequent applications for biosensor design.