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Surrogate Tissue Analysis: Genomic, Proteomic, and Metabolomic Approaches
by Michael E. Burczynski John C. RockettBoth an introduction and a fundamental reference, this book explores how to apply genomic, proteomic, and metabolomic technologies to surrogate tissue analysis. It reviews fundamental analytical issues and actual initial results generated using these technologies. The book covers transcriptional profiling (genomics), protein profiling (proteomics), methylation profiling (epigenomics), metabolite profiling (metabolomics) and additional biomarker identification methods that can be applied to surrogate tissues. This book is useful to researchers and scientists interested in applying novel methodologies for identifying biomarkers in the fields of pharmacology, toxicology, and medicine.
Mechanical Properties of Metallic Composites (Materials Engineering)
by Shojiro OchiaiProvides coverage of dispersion-hardened and fibre-reinforced alloys, addressing principal mechanisms, processing and applications. Mechanical behaviour based on dislocation theory and elastic-plastic mechanics is dealt with and data on advanced composites are provided.
High-Speed Cisco Networks: Planning, Design, and Implementation
by null John R. VaccaHigh-Speed Cisco Networks: Planning, Design, and Implementation covers LAN/WAN technology and its benefits. The book lays out Cisco's complete line of products and describes their features and best applications. It provides critical details on routers and servers, switches and hubs, security products, network management tools, ATM products, other services and programs, and Internetwork Operating Systems (IOS). Cisco's routers, hubs, and switches are the core of the Internet and today's high-speed networks. Armed with this independent evaluation, the reader can design high-speed networks that meet current needs and scale to future requirements with confidence.
Submarine Groundwater
by null Igor S. Zektser null Lorne G. Everett null Roald G. DzhamalovSustainable management of water resources is quickly increasing in importance on a global scale. An important piece of the puzzle is the characterization of marine water and determining its importance to geochemical budgets. To do this, submarine groundwater discharges must be carefully studied. Comprehensively exploring the subject, Submarine G
Liquid Crystals In Complex Geometries: Formed by Polymer And Porous Networks
by Gregory Philip Crawford Slobodan ŽumerFocusing on the applied and basic aspects of confined liquid crystals, this book provides a current treatise of the subject matter and places it in the broader context of electrooptic applications.
Dictionary of Antibiotics and Related Substances: Second Edition
by Barrie W. Bycroft David J. PayneBacterial and parasitic diseases are the second leading cause of death worldwide, according to a report by the London School of Economics. Due to the emergence of drug-resistant "superbugs," like methicillin-resistant Staphylococcus aureus (MRSA), traditional antibiotics such as penicillin and its derivatives are in danger of becoming obsolete. In an effort to combat this problem, pharmaceutical companies continue to research new and effective antibiotics. The Dictionary of Antibiotics and Related Substances, Second Edition is a definitive reference work dealing with this crucially important class of biochemicals. It consists of a comprehensive survey of the antibiotic field, providing a single-volume resource and a significant update to the first edition published in 1988. Each dictionary entry contains the chemical name and synonyms, CAS Number, chemical structure, biological activity, and a concise bibliography.Entries include naturally occurring antibiotics, such as the beta-lactams (penicillins, cephalosporins, and carbapenems) and aminoglycosides; semisynthetic antibiotics—the most common type available—modified chemically from original compounds found in nature; and synthetic antibiotics, including the sulfonamides, the quinolones, and the oxazolidinones. It is estimated that there are approximately 10,000 antibiotics known, and this revised edition of the successful compilation covers all of the different classes. The dictionary also includes fully searchable downloadable resources.
Microencapsulation: Methods and Industrial Applications, Second Edition (Drugs and the Pharmaceutical Sciences)
by Simon BenitaPresenting breakthrough research pertinent to scientists in a wide range of disciplines-from medicine and biotechnology to cosmetics and pharmacy-this Second Edition provides practical approaches to complex formulation problems encountered in the development of particulate delivery systems at the micro- and nano-size level. Completely revised and e
Electromagnetic Waves, Materials, and Computation with MATLAB
by null Dikshitulu K. KalluriReadily available commercial software enables engineers and students to perform routine calculations and design without necessarily having a sufficient conceptual understanding of the anticipated solution. The software is so user-friendly that it usually produces a beautiful colored visualization of that solution, often camouflaging the fact that t
High Performance Liquid Chromatography in Phytochemical Analysis (Chromatographic Science Series)
by Monika Waksmundzka-Hajnos Joseph ShermaThe powerful, efficient technique of high performance liquid chromatography (HPLC) is essential to the standardization of plant-based drugs, identification of plant material, and creation of new herbal medicines. Filling the void in this critical area, High Performance Liquid Chromatography in Phytochemical Analysis is the first book to give a comp
Bridge Management: Proceedings of the Third International Conference
by J. E. Harding G.E.R. Parke M. J. RyallThis volume contains the papers presented at the Third International Conference on Bridge Management, held at the University of Surrey, Guildford, UK on 14-17 April 1996.
Understanding Drug Release and Absorption Mechanisms: A Physical and Mathematical Approach
by null Mario Grassi null Gabriele Grassi null Romano Lapasin null Italo ColomboDemand for better reliability from drug delivery systems has caused designers and researchers to move away from trial-and-error approaches and toward model-based methods of product development. Developing such models requires cross-disciplinary physical, mathematical, and physiological knowledge. Combining these areas under a single cover, Under
Hydrodynamics VI: Proceedings of the 6th International Conference on Hydrodynamics, Perth, Western Australia, 24-26 November 2004
by Liang Cheng Kervin YeowThe International Conference on Hydrodynamics is an increasingly important event at which academics, researchers and practitioners can exchange new ideas and their research findings. This volume contains papers from the 2004 conference covering a wide range of subjects within hydrodynamics, including traditional engineering, architectural and mecha
Pressure-Sensitive Design, Theoretical Aspects
by null Istvan BenedekGrowing interest in the formulation of pressure-sensitive adhesives as described in the first edition of this book ( Pressure-Sensitive Formulation, VSP, 2000) required a new, enlarged edition including the design of pressure-sensitive adhesives as a separate volume. Developments in the understanding of pressure sensitivity were necessary to use ma
Multi-purpose High-rise Towers and Tall Buildings
by H. R. Viswanath J.J.A. Tolloczko J. N. ClarkeInterest continues to develop in the design and construction of high-rise towers and tall buildings, structures with heights ranging from 75m to 500m and even more. This volume presents the papers from the third in a series of international conferences on the subject, organised by the International Federation of High-rise Structures. The papers hav
Assembly Processes: Finishing, Packaging, and Automation (Handbook of Manufacturing Engineering, Second Edition)
by Richard CrowsonToday's fast-paced manufacturing culture demands a handbook that provides how-to, no-holds-barred, no-frills information. Completely revised and updated, the Handbook of Manufacturing Engineering is now presented in four volumes. Keeping the same general format as the first edition, this second edition not only provides more information but makes i
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades (Frontiers in Neuroscience)
by Wolfgang B. Liedtke Stefan HellerSince the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Medicinal Protein Engineering
by Yury E. KhudyakovAn All-Inclusive Review of the Achievements and Trends in the Fast-Growing Protein Engineering Field From humble beginnings like making fire for mere survival, engineering now steadfastly penetrates all aspects of our lives and even life itself at the molecular level. Protein engineering is a molecular biological discipline focused on designing and
Stabilization and Solidification of Hazardous, Radioactive, and Mixed Wastes
by Roger D. Spence Caijun ShiThe development of stabilization and solidification techniques in the field of waste treatment reflects the efforts to better protect human health and the environment with modern advances in materials and technology. Stabilization and Solidification of Hazardous, Radioactive, and Mixed Wastes provides comprehensive information including case studie
Wavelets, Images, and Surface Fitting
by Pierre-Jean Laurent Alain Le Méhauté Larry L. SchumakerThis volume documents the results and presentations relating to the use of wavelet theory and other methods in surface fitting and image reconstruction of the Second International Conference on Curves and Surfaces, held in Chamonix in 1993. The papers represent directions for future research and development in many areas of application.
DNA and RNA Modification Enzymes: Structure, Mechanism, Function and Evolution
by null Henri GrosjeanThis volume is a timely and comprehensive description of the many facets of DNA and RNA modification-editing processes and to some extent repair mechanisms. Each chapter offers fundamental principles as well as up to date information on recent advances in the field (up to end 2008). They ended by a shortconclusion and future prospect' section and
Validating Pharmaceutical Systems: Good Computer Practice in Life Science Manufacturing
by John AndrewsAll too often, the words "computer validation" strike terror into the hearts of those new to the process and may even cause those familiar with it to tremble. Validating Pharmaceutical Systems: Good Computer Practice in Life Science Manufacturing delineates GCP, GLP, and GMP regulatory requirements and provides guidance from seasoned practitioners
Nanoparticle Assemblies and Superstructures
by Nicholas A. KotovCubes, triangular prisms, nano-acorn, nano-centipedes, nanoshells, nano-whiskers. . . . Now that we can create nanoparticles in a wide variety of shapes and morphologies, comes the next challenge: finding ways to organize this collection of particles into larger and more complex systems. Nanoparticle Assemblies and Superstructures, edit
Pediatric Radiotherapy Planning and Treatment
by null Arthur J. OlchBy becoming knowledgeable about optimal treatment methods designed specifically for childhood cancers, members of a radiotherapy team can help improve both pediatric cancer survival statistics and patients' quality of life. Pediatric Radiotherapy Planning and Treatment is the first single, focused resource available for health care providers to acc
Air Contaminants, Ventilation, and Industrial Hygiene Economics: The Practitioner's Toolbox and Desktop Handbook
by null Roger Lee WabekeThere is nothing more devastating to baseless opinions than good numbers. Air Contaminants, Ventilation, and Industrial Hygiene Economics: The Practitioner's Toolbox and Desktop Handbook helps you obtain "good numbers" on your quest to squash shabby opinions with sound advice. It details real-world applications of good numbers to foster improvement
Obstructive Sleep Apnea: Diagnosis and Treatment (Sleep Disorders)
by Clete A. KushidaMore than 18 million Americans have Obstructive Sleep Apnea (OSA), but more than 90% of cases still remain undiagnosed. This source offers a thorough review of key considerations in the identification and treatment of OSA, and discusses issues often unaddressed in other publications on the topic, such as gender, age, drug interactions, and associat